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Drug Evaluations

Albiglutide: a new GLP-1 analog for the treatment of type 2 diabetes

, PharmD & , PharmD
Pages 801-806 | Published online: 02 Apr 2010

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Eun Ji Park, Sung Mook Lim, Kang Choon Lee & Dong Hee Na. (2016) Exendins and exendin analogs for diabetic therapy: a patent review (2012-2015). Expert Opinion on Therapeutic Patents 26:7, pages 833-842.
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Irl B. Hirsch, Doron Schneider, Aaron King, William H. Polonsky, Timothy S. Reid, Jay Shubrook, Carol A. Verderese, Jeffrey Wallace & Matthew C. Riddle. (2014) A Short-Acting GLP-1 Analog or Prandial Insulin to Supplement Basal Insulin?—Moving Toward Personalized Management of Type 2 Diabetes Mellitus. Postgraduate Medicine 126:3, pages 135-144.
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Malcolm A. Young, Jeffrey A. Wald, Jessica E. Matthews, Fred Yang & Rickey R. Reinhardt. (2014) Effect of Renal Impairment on the Pharmacokinetics, Efficacy, and Safety of Albiglutide. Postgraduate Medicine 126:3, pages 35-46.
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Tracy Setji & Mark Feinglos. (2013) Albiglutide: clinical overview of a long-acting GLP-1 receptor agonist in the treatment of Type 2 diabetes. Expert Review of Endocrinology & Metabolism 8:3, pages 229-238.
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Alan J Garber. (2012) Novel GLP-1 receptor agonists for diabetes. Expert Opinion on Investigational Drugs 21:1, pages 45-57.
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Asger Lund, Filip K Knop & Tina Vilsbøll. (2011) Emerging GLP-1 receptor agonists. Expert Opinion on Emerging Drugs 16:4, pages 607-618.
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Lars Linderoth, Jacob Kofoed, János T. Kodra, Steffen Reedtz‐Runge & Thomas Kruse. 2021. Successful Drug Discovery. Successful Drug Discovery 87 110 .
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Seyed Ebrahim Alavi, Peter J. Cabot & Peter M. Moyle. (2019) Glucagon-Like Peptide-1 Receptor Agonists and Strategies To Improve Their Efficiency. Molecular Pharmaceutics 16:6, pages 2278-2295.
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Lotte Bjerre Knudsen & Jesper Lau. (2019) The Discovery and Development of Liraglutide and Semaglutide. Frontiers in Endocrinology 10.
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Roland Böttger, Daniel Knappe & Ralf Hoffmann. (2018) PEGylated prodrugs of antidiabetic peptides amylin and GLP-1. Journal of Controlled Release 292, pages 58-66.
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Michaela Gebauer & Arne Skerra. (2018) Prospects of PASylation® for the design of protein and peptide therapeutics with extended half-life and enhanced action. Bioorganic & Medicinal Chemistry 26:10, pages 2882-2887.
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Jing Han, Yiyun Wang, Qinghua Meng, Guangchao Li, Fangmin Huang, Su Wu, Yingying Fei, Feng Zhou & Junjie Fu. (2017) Design, synthesis and biological evaluation of PEGylated Xenopus glucagon-like peptide-1 derivatives as long-acting hypoglycemic agents. European Journal of Medicinal Chemistry 132, pages 81-89.
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Sergei Pechenov, Himanshu Bhattacharjee, Daniel Yin, Sachin Mittal & J. Anand Subramony. (2017) Improving drug-like properties of insulin and GLP-1 via molecule design and formulation and improving diabetes management with device & drug delivery. Advanced Drug Delivery Reviews 112, pages 106-122.
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Seungah LeeDong Yun Lee. (2017) Glucagon-like peptide-1 and glucagon-like peptide-1 receptor agonists in the treatment of type 2 diabetes. Annals of Pediatric Endocrinology & Metabolism 22:1, pages 15.
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Chris de Graaf, Dan Donnelly, Denise Wootten, Jesper Lau, Patrick M. Sexton, Laurence J. Miller, Jung-Mo Ahn, Jiayu Liao, Madeleine M. Fletcher, Dehua Yang, Alastair J. H. Brown, Caihong Zhou, Jiejie Deng & Ming-Wei Wang. (2016) Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes. Pharmacological Reviews 68:4, pages 954-1013.
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Arun K. Sharma, Punniyakoti V. Thanikachalam & Satyendra K. Rajput. (2016) Albiglutide: Is a better hope against diabetes mellitus?. Biomedicine & Pharmacotherapy 77, pages 120-128.
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Ruben Vardanyan & Victor Hruby. 2016. Synthesis of Best-Seller Drugs. Synthesis of Best-Seller Drugs 419 458 .
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Agnieszka M Falinska, Tricia Tan & Stephen Bloom. (2014) Gut hormones and Type 2 diabetes mellitus. Diabetes Management 4:6, pages 501-513.
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Vladimer Darsalia, David Nathanson, Thomas Nyström, Thomas Klein, Åke Sjöholm & Cesare Patrone. (2014) GLP-1R activation for the treatment of stroke: Updating and future perspectives. Reviews in Endocrine and Metabolic Disorders 15:3, pages 233-242.
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Bo Ahrén, Susan L. Johnson, Murray Stewart, Deborah T. CirkelFred Yang, Caroline Perry & Mark N. Feinglos. (2014) HARMONY 3: 104-Week Randomized, Double-Blind, Placebo- and Active-Controlled Trial Assessing the Efficacy and Safety of Albiglutide Compared With Placebo, Sitagliptin, and Glimepiride in Patients With Type 2 Diabetes Taking Metformin. Diabetes Care 37:8, pages 2141-2148.
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Ralph A. DeFronzo, Curtis L. Triplitt, Muhammad Abdul-Ghani & Eugenio Cersosimo. (2014) Novel Agents for the Treatment of Type 2 Diabetes. Diabetes Spectrum 27:2, pages 100-112.
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I. B. Hirsch, J. B. Buse, J. Leahy, J. B. McGill, A. Peters, H. W. Rodbard, R. R. Rubin, J. S. Skyler, C. A. Verderese & M. C. Riddle. (2014) Options for prandial glucose management in type 2 diabetes patients using basal insulin: addition of a short-acting GLP-1 analogue versus progression to basal-bolus therapy. Diabetes, Obesity and Metabolism 16:3, pages 206-214.
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Maria Tzefos, Kira Harris & Adriane Brackett. (2012) Clinical Efficacy and Safety of Once-Weekly Glucagon-Like Peptide-1 Agonists in Development for Treatment of Type 2 Diabetes Mellitus in Adults. Annals of Pharmacotherapy 46:1, pages 68-78.
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Evan M. Sisson. (2012) Liraglutide: Clinical Pharmacology and Considerations for Therapy. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 31:9, pages 896-911.
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Weike Bao, Karpagam Aravindhan, Hasan Alsaid, Thimmaiah Chendrimada, Matthew Szapacs, David R. Citerone, Mark R. Harpel, Robert N. Willette, John J. Lepore & Beat M. Jucker. (2011) Albiglutide, a Long Lasting Glucagon-Like Peptide-1 Analog, Protects the Rat Heart against Ischemia/Reperfusion Injury: Evidence for Improving Cardiac Metabolic Efficiency. PLoS ONE 6:8, pages e23570.
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Chinmay S. Marathe, Christopher K. Rayner, Karen L. Jones & Michael Horowitz. (2011) Effects of GLP-1 and Incretin-Based Therapies on Gastrointestinal Motor Function. Experimental Diabetes Research 2011, pages 1-10.
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