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Expert Opinion on Biological Therapy Volume 11, 2011 - Issue 11
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Original Research

A pilot safety trial investigating a vector-based vaccine targeting carcinoembryonic antigen in combination with radiotherapy in patients with gastrointestinal malignancies metastatic to the liver

James L GulleyNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Laboratory of Tumor Immunology and Biology, 10 Center Dr, 8B09 MSC 1750, Bethesda, MD 20892, USA+1 301 435 2956; +1 301 480 5094;[email protected];National Cancer Institute, National Institutes of Health, Center for Cancer Research, Medical Oncology Branch, Bethesda, MD 20892, USA
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Ravi A MadanNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Laboratory of Tumor Immunology and Biology, 10 Center Dr, 8B09 MSC 1750, Bethesda, MD 20892, USA+1 301 435 2956; +1 301 480 5094;[email protected];National Cancer Institute, National Institutes of Health, Center for Cancer Research, Medical Oncology Branch, Bethesda, MD 20892, USA
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Kwong-Yok TsangNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Laboratory of Tumor Immunology and Biology, 10 Center Dr, 8B09 MSC 1750, Bethesda, MD 20892, USA+1 301 435 2956; +1 301 480 5094;[email protected]
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Philip M ArlenNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Laboratory of Tumor Immunology and Biology, 10 Center Dr, 8B09 MSC 1750, Bethesda, MD 20892, USA+1 301 435 2956; +1 301 480 5094;[email protected];National Cancer Institute, National Institutes of Health, Center for Cancer Research, Medical Oncology Branch, Bethesda, MD 20892, USA
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Kevin CamphausenNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Radiation Oncology Branch, Bethesda, MD 20892, USA
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Mahsa MohebtashNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Medical Oncology Branch, Bethesda, MD 20892, USA
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Mitchell KamravaNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Radiation Oncology Branch, Bethesda, MD 20892, USA
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Jeffrey SchlomNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Laboratory of Tumor Immunology and Biology, 10 Center Dr, 8B09 MSC 1750, Bethesda, MD 20892, USA+1 301 435 2956; +1 301 480 5094;[email protected]
&
Deborah CitrinNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Radiation Oncology Branch, Bethesda, MD 20892, USA
 show all
Pages 1409-1418 | Published online: 28 Aug 2011

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Klara Soukup & Xinhui Wang. (2015) Radiation meets immunotherapy – a perfect match in the era of combination therapy?. International Journal of Radiation Biology 91:4, pages 299-305.
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Sofia R Gameiro, Momodou L Jammeh & James W Hodge. (2013) Cancer vaccines targeting carcinoembryonic antigen: state-of-the-art and future promise. Expert Review of Vaccines 12:6, pages 617-629.
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Joseph W Kim & James L Gulley. (2012) Poxviral vectors for cancer immunotherapy. Expert Opinion on Biological Therapy 12:4, pages 463-478.
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Articles from other publishers (12)

Tyrillshall S. T. Damiana & Simone U. Dalm. (2021) Combination Therapy, a Promising Approach to Enhance the Efficacy of Radionuclide and Targeted Radionuclide Therapy of Prostate and Breast Cancer. Pharmaceutics 13:5, pages 674.
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Charalampos S. Floudas, Gagandeep Brar, Donna Mabry-Hrones, Austin G. Duffy, Bradford Wood, Elliot Levy, Venkatesh Krishnasamy, Suzanne Fioravanti, Cecilia M. Bonilla, Melissa Walker, Maria Pia Morelli, David E. Kleiner, Seth M. Steinberg, William D. Figg, Tim F. Greten & Changqing Xie. (2019) A Pilot Study of the PD-1 Targeting Agent AMP-224 Used With Low-Dose Cyclophosphamide and Stereotactic Body Radiation Therapy in Patients With Metastatic Colorectal Cancer. Clinical Colorectal Cancer 18:4, pages e349-e360.
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Ruben S. A. Goedegebuure, Leonie K. de Klerk, Adam J. Bass, Sarah Derks & Victor L. J. L. Thijssen. (2019) Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer?. Frontiers in Immunology 9.
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Mahsa Keshavarz-Fathi & Nima Rezaei. 2019. Vaccines for Cancer Immunotherapy. Vaccines for Cancer Immunotherapy 161 170 .
Benedetto Farsaci, Renee N. Donahue, Italia Grenga, Lauren M. Lepone, Peter S. Kim, Brendan Dempsey, Janet C. Siebert, Nuhad K. Ibrahim, Ravi A. Madan, Christopher R. Heery, James L. Gulley & Jeffrey Schlom. (2016) Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy. Cancer Immunology Research 4:9, pages 755-765.
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Sofia R. Gameiro, Anthony S. Malamas, Michael B. Bernstein, Kwong Y. Tsang, April Vassantachart, Narayan Sahoo, Ramesh Tailor, Rajesh Pidikiti, Chandan P. Guha, Stephen M. Hahn, Sunil Krishnan & James W. Hodge. (2016) Tumor Cells Surviving Exposure to Proton or Photon Radiation Share a Common Immunogenic Modulation Signature, Rendering Them More Sensitive to T Cell–Mediated Killing. International Journal of Radiation Oncology*Biology*Physics 95:1, pages 120-130.
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Rahim Ahmadi & Sedigheh Molaei. (2015) The Effects of Co-administration of Immobilization Stress and Aloe vera on Serum Carcinoembryonic Antigen in Rats. Zahedan Journal of Research in Medical Sciences 17:3.
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Charlie Garnett-Benson, James W. Hodge & Sofia R. Gameiro. (2015) Combination Regimens of Radiation Therapy and Therapeutic Cancer Vaccines: Mechanisms and Opportunities. Seminars in Radiation Oncology 25:1, pages 46-53.
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Caroline Jochems, Jeffrey Schlom & James L. Gulley. 2014. Novel Technologies for Vaccine Development. Novel Technologies for Vaccine Development 291 327 .
Jordan T Becker & Douglas G McNeel. (2013) Presence of antigen-specific somatic allelic mutations and splice variants do not predict for immunological response to genetic vaccination. Journal for ImmunoTherapy of Cancer 1:1.
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Kyong Joo LeeSeung Woo YiMoon Jae ChungSeung Woo ParkSi Young SongJae Bock ChungJeong Youp Park. (2013) Serum CA 19-9 and CEA Levels as a Prognostic Factor in Pancreatic Adenocarcinoma. Yonsei Medical Journal 54:3, pages 643.
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Ravi A. Madan, Marijo Bilusic, Christopher Heery, Jeffrey Schlom & James L. Gulley. (2012) Clinical Evaluation of TRICOM Vector Therapeutic Cancer Vaccines. Seminars in Oncology 39:3, pages 296-304.
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