Advanced search
Publication Cover
Expert Opinion on Biological Therapy Volume 13, 2013 - Issue 1
Submit an article Journal homepage
515
Views
33
CrossRef citations to date
0
Altmetric
Reviews

The potential of ghrelin in the treatment of cancer cachexia

Josep M ArgilésCancer Research Group, Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08028-Barcelona, Spain+34 934021002; +34 934021559; [email protected];Institut de Biomedicina de la Universitat de Barcelona, Barcelona, Spain
&
Britta StemmlerInstitut de Biomedicina de la Universitat de Barcelona, Barcelona, Spain
Pages 67-76 | Published online: 18 Oct 2012

Citations (33)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Laurent Salade, Nathalie Wauthoz, Magali Deleu, Marjorie Vermeersch, Carine De Vriese, Karim Amighi & Jonathan Goole. (2017) Development of coated liposomes loaded with ghrelin for nose-to-brain delivery for the treatment of cachexia. International Journal of Nanomedicine 12, pages 8531-8543.
Read now
Hongjie Zhang & Jose M Garcia. (2015) Anamorelin hydrochloride for the treatment of cancer-anorexia-cachexia in NSCLC. Expert Opinion on Pharmacotherapy 16:8, pages 1245-1253.
Read now
Alessio Molfino, Gianfranco Gioia & Maurizio Muscaritoli. (2013) The hunger hormone ghrelin in cachexia. Expert Opinion on Biological Therapy 13:4, pages 465-468.
Read now

Articles from other publishers (30)

G. R. Bikbavova, M. A. Livzan & D. V. Tikhonravova. (2023) All you need to know about sarcopenia: a short guide for an internal medicine physician in questions and answers. Bulletin of Siberian Medicine 22:3, pages 88-97.
Crossref
Da Woon Kim & Sang Heon Song. (2023) Sarcopenia in chronic kidney disease: from bench to bedside. The Korean Journal of Internal Medicine 38:3, pages 303-321.
Crossref
Josep M. Argilés, Francisco J. López-Soriano, Britta Stemmler & Silvia Busquets. (2023) Cancer-associated cachexia — understanding the tumour macroenvironment and microenvironment to improve management. Nature Reviews Clinical Oncology 20:4, pages 250-264.
Crossref
Pengfei Cui, Xiaoyi Li, Caihua Huang, Qinxi Li & Donghai Lin. (2022) Metabolomics and its Applications in Cancer Cachexia. Frontiers in Molecular Biosciences 9.
Crossref
Myung-Rae Cho, Sungho Lee & Suk-Kyoon Song. (2022) A Review of Sarcopenia Pathophysiology, Diagnosis, Treatment and Future Direction. Journal of Korean Medical Science 37:18.
Crossref
Sajad Fakhri, Sana Piri & Haroon Khan. 2022. The Role of Phytonutrients in Metabolic Disorders. The Role of Phytonutrients in Metabolic Disorders 397 417 .
Satoshi Hamauchi, Junji Furuse, Toshimi Takano, Yoshinori Munemoto, Ken Furuya, Hideo Baba, Manabu Takeuchi, Yasuhiro Choda, Takashi Higashiguchi, Tateaki Naito, Kei Muro, Koichi Takayama, Shusuke Oyama, Toru Takiguchi, Naoyuki Komura & Kazuo Tamura. (2019) A multicenter, open‐label, single‐arm study of anamorelin (ONO‐7643) in advanced gastrointestinal cancer patients with cancer cachexia. Cancer 125:23, pages 4294-4302.
Crossref
Merve Erdem, Diana Möckel, Sandra Jumpertz, Cathleen John, Athanassios Fragoulis, Ines Rudolph, Johanna Wulfmeier, Jochen Springer, Henrike Horn, Marco Koch, Georg Lurje, Twan Lammers, Steven Olde Damink, Gregory Kroft, Felix Gremse & Thorsten Cramer. (2019) Macrophages protect against loss of adipose tissue during cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle 10:5, pages 1128-1142.
Crossref
Josep M. Argilés, Sílvia Busquets & Francisco Javier López-Soriano. (2019) Cancer cachexia, a clinical challenge. Current Opinion in Oncology 31:4, pages 286-290.
Crossref
Mahalaqua Nazli Khatib, Anuraj H Shankar, Richard Kirubakaran, Abhay Gaidhane, Shilpa Gaidhane, Padam Simkhada & Zahiruddin Quazi Syed. (2018) Ghrelin for the management of cachexia associated with cancer. Cochrane Database of Systematic Reviews 2020:8.
Crossref
Shengguang Ding, Qiying Dai, Haitao Huang, Yiming Xu & Chongjun Zhong. 2018. Muscle Atrophy. Muscle Atrophy 3 19 .
Josep M. Argilés, Francisco Javier López-Soriano, Britta Stemmler & Sílvia Busquets. (2017) Novel targeted therapies for cancer cachexia. Biochemical Journal 474:16, pages 2663-2678.
Crossref
Elena Conte, Giulia Maria Camerino, Antonietta Mele, Michela De Bellis, Sabata Pierno, Francesco Rana, Adriano Fonzino, Roberta Caloiero, Laura Rizzi, Elena Bresciani, Khoubaib Ben Haj Salah, Jean-Alain Fehrentz, Jean Martinez, Arcangela Giustino, Maria Addolorata Mariggi?, Mauro Coluccia, Domenico Tricarico, Marcello Diego Lograno, Annamaria De Luca, Antonio Torsello, Diana Conte & Antonella Liantonio. (2017) Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia. Journal of Cachexia, Sarcopenia and Muscle 8:3, pages 386-404.
Crossref
Nicholas Fuggle, Sarah Shaw, Elaine Dennison & Cyrus Cooper. (2017) Sarcopenia. Best Practice & Research Clinical Rheumatology 31:2, pages 218-242.
Crossref
Takao Ohnuma. 2016. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine 1 10 .
Keita Tagami, Yohei Kashiwase, Akinobu Yokoyama, Hitomi Nishimura, Kanako Miyano, Masami Suzuki, Seiji Shiraishi, Motohiro Matoba, Yuichiro Ohe & Yasuhito Uezono. (2016) The atypical antipsychotic, olanzapine, potentiates ghrelin-induced receptor signaling: An in vitro study with cells expressing cloned human growth hormone secretagogue receptor. Neuropeptides 58, pages 93-101.
Crossref
John E. Morley. (2015) Pharmacologic Options for the Treatment of Sarcopenia. Calcified Tissue International 98:4, pages 319-333.
Crossref
J. Compston & K.C.H. Fearon. (2015) Emerging therapeutic concepts for muscle and bone preservation/formation. Bone 80, pages 157-161.
Crossref
Marion E. Couch, Kim Dittus, Michael J. Toth, Monte S. Willis, Denis C. Guttridge, Jonathan R. George, Eric Y. Chang, Christine G. Gourin & Hirak Der-Torossian. (2015) Cancer cachexia update in head and neck cancer: Pathophysiology and treatment. Head & Neck 37:7, pages 1057-1072.
Crossref
Philip T. Leese, John M. Trang, Robert A. Blum & Eleanor de Groot. (2015) An open‐label clinical trial of the effects of age and gender on the pharmacodynamics, pharmacokinetics and safety of the ghrelin receptor agonist anamorelin. Clinical Pharmacology in Drug Development 4:2, pages 112-120.
Crossref
Claudio Pietra, Yasuhiro Takeda, Naoko Tazawa-Ogata, Masashi Minami, Xia Yuanfeng, Elizabeth Manning Duus & Robert Northrup. (2014) Anamorelin HCl (ONO‐7643), a novel ghrelin receptor agonist, for the treatment of cancer anorexia‐cachexia syndrome: preclinical profile. Journal of Cachexia, Sarcopenia and Muscle 5:4, pages 329-337.
Crossref
Yutaka Fujiwara, Takashi Kobayashi, Naoko Chayahara, Yoshinori Imamura, Masanori Toyoda, Naomi Kiyota, Toru Mukohara, Shin Nishiumi, Takeshi Azuma, Masaru Yoshida & Hironobu Minami. (2014) Metabolomics Evaluation of Serum Markers for Cachexia and Their Intra-Day Variation in Patients with Advanced Pancreatic Cancer. PLoS ONE 9:11, pages e113259.
Crossref
Flavia Prodam & Nicoletta Filigheddu. (2014) Ghrelin Gene Products in Acute and Chronic Inflammation. Archivum Immunologiae et Therapiae Experimentalis 62:5, pages 369-384.
Crossref
Alessio Molfino, Alessandra Formiconi, Filippo Rossi Fanelli & Maurizio Muscaritoli. (2014) Ghrelin. Current Opinion in Clinical Nutrition and Metabolic Care 17:5, pages 471-476.
Crossref
John E. Morley, Stephan von Haehling & Stefan D. Anker. (2014) Are we closer to having drugs to treat muscle wasting disease?. Journal of Cachexia, Sarcopenia and Muscle 5:2, pages 83-87.
Crossref
Trude Rakel Balstad, Stein Kaasa & Tora Skeidsvoll Solheim. (2014) Multimodal nutrition/anabolic therapy for wasting conditions. Current Opinion in Clinical Nutrition and Metabolic Care 17:3, pages 226-235.
Crossref
Mario Perello & Jesica Raingo. 2014. Central Functions of the Ghrelin Receptor. Central Functions of the Ghrelin Receptor 65 88 .
Marie Amitani, Akihiro Asakawa, Haruka Amitani & Akio Inui. (2013) Control of food intake and muscle wasting in cachexia. The International Journal of Biochemistry & Cell Biology 45:10, pages 2179-2185.
Crossref
Chuang Tian, Lianhai Zhang, Daohu Hu & Jiafu Ji. (2013) Ghrelin induces gastric cancer cell proliferation, migration, and invasion through GHS-R/NF-κB signaling pathway. Molecular and Cellular Biochemistry 382:1-2, pages 163-172.
Crossref
Stefania Raimondo, Giulia Ronchi, Stefano Geuna, Davide Pascal, Simone Reano, Nicoletta Filigheddu & Andrea Graziani. 2013. Tissue Engineering of the Peripheral Nerve: Stem Cells and Regeneration Promoting Factors. Tissue Engineering of the Peripheral Nerve: Stem Cells and Regeneration Promoting Factors 207 221 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.