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Therapeutic vaccines for leishmaniasis

Keep up to date with the latest research on this topic with citation updates for this article.

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Thalia Pacheco-Fernandez, Hannah Markle, Chaitenya Verma, Ryan Huston, Sreenivas Gannavaram, Hira L Nakhasi & Abhay R Satoskar. (2023) Field-Deployable Treatments For Leishmaniasis: Intrinsic Challenges, Recent Developments and Next Steps. Research and Reports in Tropical Medicine 14, pages 61-85.
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Mahsa Esmaeilifallah, Hossein Khanahmad, Zahra Ghayour, Sedighe Saberi, Reza Kalantari & Seyed Hossein Hejazi. (2023) Evaluation of the antileishmanial effect of polyclonal antibodies and cationic antimicrobial peptides. Pathogens and Global Health 117:4, pages 366-380.
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Tara Emami, Seyed Mahdi Rezayat, Ali Khamesipour, Rasool Madani, Gholamreza Habibi, Mansure Hojatizade & Mahmoud Reza Jaafari. (2018) The role of MPL and imiquimod adjuvants in enhancement of immune response and protection in BALB/c mice immunized with soluble Leishmania antigen (SLA) encapsulated in nanoliposome. Artificial Cells, Nanomedicine, and Biotechnology 46:sup2, pages 324-333.
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Keerti Rawat, Narendra K Yadav, Sumit Joshi, Sneha Ratnapriya, Amogh A Sahasrabuddhe & Anuradha Dube. (2016) Management of visceral leishmaniasis with therapeutic vaccines. Vaccine: Development and Therapy 6, pages 33-45.
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Articles from other publishers (30)

Rasit Dinc. (2022) Leishmania Vaccines: the Current Situation with Its Promising Aspect for the Future. The Korean Journal of Parasitology 60:6, pages 379-391.
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Diksha Kumari, Shavi Mahajan, Parampreet Kour & Kuljit Singh. (2022) Virulence factors of Leishmania parasite: Their paramount importance in unraveling novel vaccine candidates and therapeutic targets. Life Sciences 306, pages 120829.
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Amir Javadi, Ali Khamesipour, Mohammad Ghoorchi, Mahdieh Bahrami, Alireza Khatami, Iraj Sharifi, Seyed Ebrahim Eskandari, Alireza Fekri, Mohamad Reza Aflatoonian & Alireza Firooz. (2022) Efficacy of intra-lesional injections of meglumine antimoniate once a week vs. twice a week in the treatment of cutaneous leishmaniasis caused by L. tropica in Iran: A randomized controlled clinical trial. PLOS Neglected Tropical Diseases 16:7, pages e0010569.
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Sara Rahimi, Ali khamesipour, Amir Ahmad Akhavan, Javad Rafinejad, Reza Ahmadkhaniha, Mahmood Bakhtiyari, Arshad Veysi & Kamran Akbarzadeh. (2021) The leishmanicidal effect of Lucilia sericata larval saliva and hemolymph on in vitro Leishmania tropica. Parasites & Vectors 14:1.
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Rodrigo Ochoa, Amaya Ortega-Pajares, Florencia A. Castello, Federico Serral, Darío Fernández Do Porto, Janny A. Villa-Pulgarin, Rubén E. Varela-M & Carlos Muskus. (2021) Identification of Potential Kinase Inhibitors within the PI3K/AKT Pathway of Leishmania Species. Biomolecules 11:7, pages 1037.
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Camila Alves Mota, Jully Oyama, Mariana de Souza Terron Monich, Aline Ávila Brustolin, João Vítor Perez de Souza, Letícia Sayuri Murase, Luciana Dias Ghiraldi Lopes, Thais da Silva Santos, Jorge Juarez Vieira Teixeira & Thaís Gomes Verzignassi Silveira. (2021) Three decades of clinical trials on immunotherapy for human leishmaniases: a systematic review and meta-analysis. Immunotherapy 13:8, pages 693-721.
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Mahmoud Nateghi Rostami & Ali Khamesipour. (2021) Potential biomarkers of immune protection in human leishmaniasis. Medical Microbiology and Immunology 210:2-3, pages 81-100.
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Maryam Akbari, Ahmad Oryan & Gholamreza Hatam. (2021) Immunotherapy in treatment of leishmaniasis. Immunology Letters 233, pages 80-86.
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Sneha Ratnapriya, Keerti, Narendra Kumar Yadav, Anuradha Dube & Amogh Anant Sahasrabuddhe. (2021) A Chimera of Th1 Stimulatory Proteins of Leishmania donovani Offers Moderate Immunotherapeutic Efficacy with a Th1-Inclined Immune Response against Visceral Leishmaniasis. BioMed Research International 2021, pages 1-14.
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Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Tomas Becvar, Patrick Lypaczewski, Eli Schwartz, Elizabeth Greensted, Katrien Van Bocxlaer, Marion Pasin, Kai S. Lipinski, Vivak Parkash, Greg Matlashewski, Alison M. Layton, Charles J. Lacey, Charles L. Jaffe, Petr Volf & Paul M. Kaye. (2021) Characterization of a new Leishmania major strain for use in a controlled human infection model. Nature Communications 12:1.
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Mahmoud Nateghi Rostami. (2020) CRISPR/Cas9 gene drive technology to control transmission of vector‐borne parasitic infections. Parasite Immunology 42:9.
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Leila Zaki, Fatemeh Ghaffarifar, Zohreh Sharifi, John Horton & Javid Sadraei. (2020) Effect of Imiquimod on Tachyzoites of Toxoplasma gondii and Infected Macrophages in vitro and in BALB/c Mice. Frontiers in Cellular and Infection Microbiology 10.
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Pragya Misra & Shailza Singh. 2020. Systems and Synthetic Immunology. Systems and Synthetic Immunology 1 52 .
Georcki Ropón-Palacios, Manuel E. Chenet-Zuta, Kewin Otazu, Gustavo E. Olivos-Ramirez & Ihosvany Camps. (2019) Novel multi-epitope protein containing conserved epitopes from different Leishmania species as potential vaccine candidate: Integrated immunoinformatics and molecular dynamics approach. Computational Biology and Chemistry 83, pages 107157.
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Jéssica Cristina dos Santos, Ana Marina Barroso de Figueiredo, Muriel Vilela Teodoro Silva, Branko Cirovic, L. Charlotte J. de Bree, Michelle S.M.A. Damen, Simone J.C.F.M. Moorlag, Rodrigo S. Gomes, Monique M. Helsen, Marije Oosting, Samuel T. Keating, A. Schlitzer, Mihai G. Netea, Fátima Ribeiro-Dias & Leo A.B. Joosten. (2019) β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32. Cell Reports 28:10, pages 2659-2672.e6.
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Zhenyu Wu, Lingling Wang, Jiaying Li, Lifu Wang, Zhongdao Wu & Xi Sun. (2019) Extracellular Vesicle-Mediated Communication Within Host-Parasite Interactions. Frontiers in Immunology 9.
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Legna Colina-Vegas, Joseane Lima Prado Godinho, Thallita Coutinho, Rodrigo S. Correa, Wanderley de Souza, Juliany Cola Fernandes Rodrigues, Alzir Azevedo Batista & Maribel Navarro. (2019) Antiparasitic activity and ultrastructural alterations provoked by organoruthenium complexes against Leishmania amazonensis . New Journal of Chemistry 43:3, pages 1431-1439.
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Mohammad Moafi, Hossein Rezvan, Roya Sherkat & Roya Taleban. (2019) Leishmania vaccines entered in clinical trials: A review of literature. International Journal of Preventive Medicine 10:1, pages 95.
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Pedro Cecílio, Fabiano Oliveira & Anabela Cordeiro da Silva. 2018. Leishmaniases as Re-emerging Diseases. Leishmaniases as Re-emerging Diseases.
Yann Ayotte, François Bilodeau, Albert Descoteaux & Steven R. LaPlante. (2018) Fragment-Based Phenotypic Lead Discovery: Cell-Based Assay to Target Leishmaniasis. ChemMedChem 13:14, pages 1377-1386.
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Nahid Mortazavidehkordi, Ali Fallah, Abbas Abdollahi, Vahid Kia, Hossein Khanahmad, Zahra Ghayour Najafabadi, Nooshin Hashemi, Bahareh Estiri, Zahra Roudbari, Ali Najafi, Akbar Farjadfar & Seyed Hossein Hejazi. (2018) A lentiviral vaccine expressing KMP11-HASPB fusion protein increases immune response to Leishmania major in BALB/C. Parasitology Research 117:7, pages 2265-2273.
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Wim Adriaensen, Thomas P. C. Dorlo, Guido Vanham, Luc Kestens, Paul M. Kaye & Johan van Griensven. (2018) Immunomodulatory Therapy of Visceral Leishmaniasis in Human Immunodeficiency Virus-Coinfected Patients. Frontiers in Immunology 8.
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Nicky Didwania, Md. Shadab, Abdus Sabur & Nahid Ali. (2017) Alternative to Chemotherapy—The Unmet Demand against Leishmaniasis. Frontiers in Immunology 8.
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Anis Askarizadeh, Mahmoud Reza Jaafari, Ali Khamesipour & Ali Badiee. (2017) Liposomal adjuvant development for leishmaniasis vaccines. Therapeutic Advances in Vaccines 5:4-5, pages 85-101.
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Naomi Aronson, Barbara L Herwaldt, Michael Libman, Richard Pearson, Rogelio Lopez-Velez, Peter Weina, Edgar M Carvalho, Moshe Ephros, Selma Jeronimo & Alan Magill. (2016) Diagnosis and Treatment of Leishmaniasis: Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH). Clinical Infectious Diseases 63:12, pages e202-e264.
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Alireza Sanei-Dehkordi, Ali Khamesipour, Kamran Akbarzadeh, Amir Ahmad Akhavan, Akram Mir Amin Mohammadi, Younes Mohammadi, Yavar Rassi, Mohammad Ali Oshaghi, Zahra Alebrahim, Seyed Ebrahim Eskandari & Javad Rafinejad. (2016) Anti Leishmania activity of Lucilia sericata and Calliphora vicina maggots in laboratory models. Experimental Parasitology 170, pages 59-65.
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Abdus Sabur, Mohammad Asad & Nahid Ali. (2016) Lipid based delivery and immuno-stimulatory systems: Master tools to combat leishmaniasis. Cellular Immunology 309, pages 55-60.
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Maribel Navarro, Edgar Marchán, Alexis Maldonado, Zulay Simoni, Mariceny Velásquez, Leidi Herrera & Gonzalo Visbal. (2015) Anti-trypanosomatid activity of platinum–sterol hydrazone imidazoline complexes. Transition Metal Chemistry 40:7, pages 707-713.
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M.K. Faulde, K. Erkens & R. Dieterle. (2015) Epidemiologie und Prophylaxe der Leishmaniasis in NordafghanistanEpidemiology and prevention of leishmaniasis in northern Afghanistan. Der Hautarzt 66:5, pages 347-354.
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Carlos Gustavo Vieira de Morais, Ana Karina Castro Lima, Rodrigo Terra, Rosiane Freire dos Santos, Silvia Amaral Gonçalves Da-Silva & Patrícia Maria Lourenço Dutra. (2015) The Dialogue of the Host-Parasite Relationship: Leishmania spp. and Trypanosoma cruzi Infection . BioMed Research International 2015, pages 1-19.
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