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The use of the NIS reporter gene for optimizing oncolytic virotherapy

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Shunchuan Zhang & Samuel D Rabkin. (2021) The discovery and development of oncolytic viruses: are they the future of cancer immunotherapy?. Expert Opinion on Drug Discovery 16:4, pages 391-410.
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Altar M. Munis, Emma M. Bentley & Yasuhiro Takeuchi. (2020) A tool with many applications: vesicular stomatitis virus in research and medicine. Expert Opinion on Biological Therapy 20:10, pages 1187-1201.
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Silvia Ravera, Juan Pablo Nicola, Glicella Salazar-De Simone, Fred J. Sigworth, Erkan Karakas, L. Mario Amzel, Mario A. Bianchet & Nancy Carrasco. (2022) Structural insights into the mechanism of the sodium/iodide symporter. Nature 612:7941, pages 795-801.
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Meng Du, Ting Wang, Yaozhang Yang, Fengyi Zeng, Yue Li & Zhiyi Chen. (2022) Application of Genetically Encoded Molecular Imaging Probes in Tumor Imaging. Contrast Media & Molecular Imaging 2022, pages 1-9.
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Petrina KoumarianouCelia Fernández-MéndezDánae Fajardo-DelgadoLidia Mirella MieluPilar SantistebanAntonio De la Vieja. (2022) Basolateral Sorting of the Sodium/Iodide Symporter Is Mediated by Adaptor Protein 1 Clathrin Adaptor Complexes. Thyroid.
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M. Fawad Khan, Ebenezer Bonyah, Fahad Sameer Alshammari, Syed Muhammad Ghufran & Muhammad Sulaiman. (2022) Modelling and Analysis of Virotherapy of Cancer Using an Efficient Hybrid Soft Computing Procedure. Complexity 2022, pages 1-29.
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Shyambabu Chaurasiya, Sang-In Kim, Michael O’Leary, Anthony K. Park, Jianming Lu, Seonah Kang, Zhifang Zhang, Annie Yang, Yanghee Woo, Yuman Fong & Susanne G. Warner. (2021) Toward comprehensive imaging of oncolytic viroimmunotherapy. Molecular Therapy - Oncolytics 23, pages 303-310.
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Omeed Moaven, Christopher W. Mangieri, John A. Stauffer, Panos Z. Anastasiadis & Mitesh J. Borad. (2021) Evolving Role of Oncolytic Virotherapy: Challenges and Prospects in Clinical Practice. JCO Precision Oncology:5, pages 432-441.
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Sophie Stotz, Gregory D. Bowden, Jonathan M. Cotton, Bernd J. Pichler & Andreas Maurer. (2021) Covalent 18F-Radiotracers for SNAPTag: A New Toolbox for Reporter Gene Imaging. Pharmaceuticals 14:9, pages 897.
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Susanna C. Concilio, Stephen J. Russell & Kah-Whye Peng. (2021) A brief review of reporter gene imaging in oncolytic virotherapy and gene therapy. Molecular Therapy - Oncolytics 21, pages 98-109.
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Amir Sasan Mozaffari Nejad, Tehjeeb Noor, Ziaul Haque Munim, Mohammad Yousef Alikhani & Amir Ghaemi. (2021) A bibliometric review of oncolytic virus research as a novel approach for cancer therapy. Virology Journal 18:1.
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Matthew Glen Robertson, Benjamin Bruce Eidenschink, Eriko Iguchi, Stanislav O. Zakharkin, Christopher J. LaRocca, Ezequiel J. Tolosa, Mark J. Truty, Kari Jacobsen, Martin E. Fernandez-Zapico & Julia Davydova. (2021) Cancer imaging and therapy utilizing a novel NIS-expressing adenovirus: The role of adenovirus death protein deletion. Molecular Therapy - Oncolytics 20, pages 659-668.
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Alessia Volpe, Naga Vara Kishore Pillarsetty, Jason S. Lewis & Vladimir Ponomarev. (2021) Applications of nuclear-based imaging in gene and cell therapy: Probe considerations. Molecular Therapy - Oncolytics 20, pages 447-458.
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Susanna C. Concilio, Lukkana Suksanpaisan, Linh Pham, Kah-Whye Peng & Stephen J. Russell. (2021) Improved Noninvasive In Vivo Tracking of AAV-9 Gene Therapy Using the Perchlorate-Resistant Sodium Iodide Symporter from Minke Whale. Molecular Therapy 29:1, pages 236-243.
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Brianna L. Bullard, Brigette N. Corder & Eric A. Weaver. (2020) Species D Adenoviruses as Oncolytic Viral Vectors. Viruses 12:12, pages 1399.
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Mohsen Keshavarz, Ailar Sabbaghi, Seyed Mohammad Miri, Abolhasan Rezaeyan, Yaser Arjeini & Amir Ghaemi. (2020) Virotheranostics, a double-barreled viral gun pointed toward cancer; ready to shoot?. Cancer Cell International 20:1.
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Alejandro Llorente-Esteban, Rían W. Manville, Andrea Reyna-Neyra, Geoffrey W. Abbott, L. Mario Amzel & Nancy Carrasco. (2020) Allosteric regulation of mammalian Na+/I− symporter activity by perchlorate. Nature Structural & Molecular Biology 27:6, pages 533-539.
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Rianna Vandergaast, Sarawut Khongwichit, Huailei Jiang, Timothy R. DeGrado, Kah-Whye Peng, Duncan R. Smith, Stephen J. Russell & Lukkana Suksanpaisan. (2019) Enhanced noninvasive imaging of oncology models using the NIS reporter gene and bioluminescence imaging. Cancer Gene Therapy 27:3-4, pages 179-188.
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Qiaoshuai Lan, Shuai Xia, Qian Wang, Wei Xu, Haiyan Huang, Shibo Jiang & Lu Lu. (2020) Development of oncolytic virotherapy: from genetic modification to combination therapy. Frontiers of Medicine 14:2, pages 160-184.
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Hristina R. Zhekova, Toshie Sakuma, Ryan Johnson, Susanna C. Concilio, Patrycja J. Lech, Igor Zdravkovic, Mirna Damergi, Lukkana Suksanpaisan, Kah-Whye Peng, Stephen J. Russell & Sergei Noskov. (2020) Mapping of Ion and Substrate Binding Sites in Human Sodium Iodide Symporter (hNIS). Journal of Chemical Information and Modeling 60:3, pages 1652-1665.
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Faiq A. Shaikh, Ewelina Kurtys, Olga Kubassova & Diana Roettger. (2020) Reporter gene imaging and its role in imaging-based drug development. Drug Discovery Today 25:3, pages 582-592.
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Susanna C. Concilio, Hristina R. Zhekova, Sergei Y. Noskov & Stephen J. Russell. (2020) Inter-species variation in monovalent anion substrate selectivity and inhibitor sensitivity in the sodium iodide symporter (NIS). PLOS ONE 15:2, pages e0229085.
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Susanne G. Warner, Sang-In Kim, Shyambabu Chaurasiya, Michael P. O’Leary, Jianming Lu, Venkatesh Sivanandam, Yanghee Woo, Nanhai G. Chen & Yuman Fong. (2019) A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression. Molecular Therapy - Oncolytics 13, pages 82-92.
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Iris Kemler, Matthew K. Ennis, Claudia M. Neuhauser & David Dingli. (2019) In Vivo Imaging of Oncolytic Measles Virus Propagation with Single-Cell Resolution. Molecular Therapy - Oncolytics 12, pages 68-78.
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Mariano Martín, Romina Celeste Geysels, Victoria Peyret, Carlos Eduardo Bernal Barquero, Ana María Masini-Repiso & Juan Pablo Nicola. (2019) Implications of Na+/I- Symporter Transport to the Plasma Membrane for Thyroid Hormonogenesis and Radioiodide Therapy. Journal of the Endocrine Society 3:1, pages 222-234.
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Joshua D. Freedman, Margaret R. Duffy, Janet Lei-Rossmann, Alice Muntzer, Eleanor M. Scott, Joachim Hagel, Leticia Campo, Richard J. Bryant, Clare Verrill, Adam Lambert, Paul Miller, Brian R. Champion, Leonard W. Seymour & Kerry D. Fisher. (2018) An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells. Cancer Research 78:24, pages 6852-6865.
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Bethany Brunton, Lukkana Suksanpaisan, Hongtao Li, Qian Liu, Yinxian Yu, Alyssa Vrieze, Lianwen Zhang, Nathan Jenks, Huailei Jiang, Timothy R. DeGrado, Chunfeng Zhao, Stephen J. Russell & Kah-Whye Peng. (2018) New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging. Scientific Reports 8:1.
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Antonio De la Vieja & Pilar Santisteban. (2018) Role of iodide metabolism in physiology and cancer. Endocrine-Related Cancer 25:4, pages R225-R245.
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Zi J. WuFeng R. TangZhao-Wu MaXiao-Chun PengYing XiangYanling ZhangJingbo KangJiafu JiXiao Q. LiuXian-Wang WangHong-Wu XinBo X. Ren. (2018) Oncolytic Viruses for Tumor Precision Imaging and Radiotherapy. Human Gene Therapy 29:2, pages 204-222.
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Shruthi Naik, Gina D. Galyon, Nathan J. Jenks, Michael B. Steele, Amber C. Miller, Sara D. Allstadt, Lukkana Suksanpaisan, Kah Whye Peng, Mark J. Federspiel, Stephen J. Russell & Amy K. LeBlanc. (2018) Comparative Oncology Evaluation of Intravenous Recombinant Oncolytic Vesicular Stomatitis Virus Therapy in Spontaneous Canine Cancer. Molecular Cancer Therapeutics 17:1, pages 316-326.
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Huailei Jiang, Nicholas R. Schmit, Alex R. Koenen, Aditya Bansal, Mukesh K. Pandey, Robert B. Glynn, Bradley J. Kemp, Kera L. Delaney, Angela Dispenzieri, Jamie N. Bakkum-Gamez, Kah-Whye Peng, Stephen J. Russell, Tina M. Gunderson, Val J. Lowe & Timothy R. DeGrado. (2017) Safety, pharmacokinetics, metabolism and radiation dosimetry of 18F-tetrafluoroborate (18F-TFB) in healthy human subjects. EJNMMI Research 7:1.
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Susanne G. Warner, Michael P. O’Leary & Yuman Fong. (2017) Therapeutic oncolytic viruses: clinical advances and future directions. Current Opinion in Oncology 29:5, pages 359-365.
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Daniel F. Pease & Robert A. Kratzke. (2017) Oncolytic Viral Therapy for Mesothelioma. Frontiers in Oncology 7.
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Viorel Simion, Julien Sobilo, Rudy Clemoncon, Sharuja Natkunarajah, Safia Ezzine, Florence Abdallah, Stephanie Lerondel, Chantal Pichon & Patrick Baril. (2017) Positive radionuclide imaging of miRNA expression using RILES and the human sodium iodide symporter as reporter gene is feasible and supports a protective role of miRNA-23a in response to muscular atrophy. PLOS ONE 12:5, pages e0177492.
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Stephen J. Russell & Kah-Whye Peng. (2017) Oncolytic Virotherapy: A Contest between Apples and Oranges. Molecular Therapy 25:5, pages 1107-1116.
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Sarah Urnauer, Kathrin Klutz, Geoffrey K. Grünwald, Stephan Morys, Nathalie Schwenk, Christian Zach, Franz-Josef Gildehaus, Wolfgang Rödl, Manfred Ogris, Ernst Wagner & Christine Spitzweg. (2017) Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes. The Journal of Gene Medicine 19:5, pages e2957.
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Justin Maroun, Miguel Muñoz-Alía, Arun Ammayappan, Autumn Schulze, Kah-Whye Peng & Stephen Russell. (2017) Designing and building oncolytic viruses. Future Virology 12:4, pages 193-213.
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Silvia RaveraAndrea Reyna-NeyraGiuseppe FerrandinoL. Mario Amzel & Nancy Carrasco. (2017) The Sodium/Iodide Symporter (NIS): Molecular Physiology and Preclinical and Clinical Applications. Annual Review of Physiology 79:1, pages 261-289.
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Sangeet Lal, Kah-Whye Peng, Michael B. Steele, Nathan Jenks, Hong Ma, Gary Kohanbash, Joanna J. Phillips & Corey Raffel. (2016) Safety Study: Intraventricular Injection of a Modified Oncolytic Measles Virus into Measles-Immune, hCD46-Transgenic, IFNαRko Mice. Human Gene Therapy Clinical Development 27:4, pages 145-151.
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Lianwen Zhang, Michael B Steele, Nathan Jenks, Jacquelyn Grell, Marshall Behrens, Rebecca Nace, Shruthi Naik, Mark J Federspiel, Stephen J Russell & Kah-Whye Peng. (2016) Robust Oncolytic Virotherapy Induces Tumor Lysis Syndrome and Associated Toxicities in the MPC-11 Plasmacytoma Model. Molecular Therapy 24:12, pages 2109-2117.
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Sarah Urnauer, Stephan Morys, Ana Krhac Levacic, Andrea M Müller, Christina Schug, Kathrin A Schmohl, Nathalie Schwenk, Christian Zach, Janette Carlsen, Peter Bartenstein, Ernst Wagner & Christine Spitzweg. (2016) Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene. Molecular Therapy 24:8, pages 1395-1404.
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Christopher J. LaRocca & Julia Davydova. (2016) Oncolytic Virotherapy Increases the Detection of Microscopic Metastatic Disease at Time of Staging Laparoscopy for Pancreatic Adenocarcinoma. EBioMedicine 7, pages 15-16.
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