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Expert Opinion on Biological Therapy Volume 16, 2016 - Issue 2
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Drug Evaluations

Ixekizumab: a new anti-IL-17A monoclonal antibody therapy for moderate-to severe plaque psoriasis

Andrew BlauveltOregon Medical Research Center, Portland, OR, USACorrespondence[email protected]
Pages 255-263 | Received 23 Sep 2015, Accepted 14 Dec 2015, Published online: 25 Jan 2016

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Angelo Ruggiero, Matteo Megna, Gabriella Fabbrocini, Luigi Fornaro & Alessia Villani. (2022) Drug safety evaluation of ixekizumab for psoriasis: a review of the current knowledge. Expert Opinion on Drug Safety 21:10, pages 1249-1257.
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Lluís Puig. (2020) The safety of ixekizumab in psoriasis drug therapy. Expert Opinion on Drug Safety 19:2, pages 117-130.
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Eric Toussirot. (2018) Ixekizumab: an anti- IL-17A monoclonal antibody for the treatment of psoriatic arthritis. Expert Opinion on Biological Therapy 18:1, pages 101-107.
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Cole R. Formslag, Lei Zhao, Aidan J. Heslin, Cade C. Lewis, Caleb W. Miller, Qian Bai, Mark R. Wakefield & Yujiang Fang. (2023) The past, present, and future of immunotherapy for colorectal cancer. Medical Oncology 40:3.
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Vivaswath S. Ayyar, Jong Bong Lee, Weirong Wang, Meghan Pryor, Yanli Zhuang, Thomas Wilde & An Vermeulen. (2022) Minimal Physiologically-Based Pharmacokinetic (mPBPK) Metamodeling of Target Engagement in Skin Informs Anti-IL17A Drug Development in Psoriasis. Frontiers in Pharmacology 13.
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Min Wu, Hong Zhang, Qianqian Li, Hong Chen, Min Fang, Lizhi Yang & Yanhua Ding. (2022) Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of the QX002N anti-IL-17 Monoclonal Antibody: A Phase I, Randomized, Double-Blind, Single Ascending Dose Study in Healthy Chinese Volunteers. Frontiers in Pharmacology 12.
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Michael Carter, Sophie Casey, Gerard W. O’Keeffe, Louise Gibson & Deirdre M. Murray. (2021) Mid-gestation cytokine profiles in mothers of children affected by autism spectrum disorder: a case–control study. Scientific Reports 11:1.
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Carmen RODRÍGUEZ-CERDEIRA, José L. GONZÁLEZ-CESPÓN, Erick MARTÍNEZ-HERRERA, Miguel CARNERO-GREGORIO, Adriana LÓPEZ-BARCENAS, Alexey SERGEEV & Ditte M. SAUNTE. (2021) Candida infections in patients with psoriasis and psoriatic arthritis treated with interleukin-17 inhibitors and their practical management. Italian Journal of Dermatology and Venereology 156:5.
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Chao Liu, Ruiqi Liu, Bojun Wang, Jie Lian, Yang Yao, Haoxiu Sun, Chunhui Zhang, Lin Fang, Xin Guan, Jiaqi Shi, Shuling Han, Fei Zhan, Shengnan Luo, Yuanfei Yao, Tongsen Zheng & Yanqiao Zhang. (2021) Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer. Journal for ImmunoTherapy of Cancer 9:1, pages e001895.
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Lula María Nieto‐Benito, Ana Mateos‐Mayo, Rosa Romero‐Jiménez & Ofelia Baniandrés‐Rodríguez. (2020) Anemia in a psoriatic patient treated with ixekizumab. The Journal of Dermatology 47:5.
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YingYing Hu, Jing Guo, Li Yin, Jie Tu & ZhiQiang Yin. (2019) Tacrolimus Inhibits TNF-α/IL-17A-Produced pro-Inflammatory Effect on Human Keratinocytes by Regulating IκBζ. Inflammation 43:2, pages 692-700.
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Sepideh Razi, Behnoud Baradaran Noveiry, Mahsa Keshavarz-Fathi & Nima Rezaei. (2019) IL-17 and colorectal cancer: From carcinogenesis to treatment. Cytokine 116, pages 7-12.
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Kristian Reich, Kimberley Jackson, Susan Ball, Sandra Garces, Lisa Kerr, Laiyi Chua, Talia M. Muram & Andrew Blauvelt. (2018) Ixekizumab Pharmacokinetics, Anti-Drug Antibodies, and Efficacy through 60 Weeks of Treatment of Moderate to Severe Plaque Psoriasis. Journal of Investigative Dermatology 138:10, pages 2168-2173.
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Jane Grills. (2018) Interleukin-23 in Psoriasis: Integrating New Therapies in the Current Treatment Landscape. European Medical Journal, pages 22-29.
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Adriane A Levin & Jeffrey M Sobell. (2017) Update on IL-17 Inhibitors for Psoriasis. Current Dermatology Reports 6:2, pages 121-128.
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Lisa M. Sedger, Charani Ranasinghe, Michael F. McDermott & Parisa Asvadi. 2017. Immunotherapy - Myths, Reality, Ideas, Future. Immunotherapy - Myths, Reality, Ideas, Future.
Shivani P. Reddy, Vidhi V. Shah & Jashin J. Wu. 2016. Therapy for Severe Psoriasis. Therapy for Severe Psoriasis 153 162 .

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