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Human cancer gene therapy with cytokine gene-modified cells

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Pages 1595-1607 | Published online: 23 Feb 2005

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Andrzej Mackiewicz, Jacek Mackiewicz, Piotr J. Wysocki, Maciej Wiznerowicz, Malgorzata Kapcinska, Maria Laciak, Stefan Rose-John, Dariusz Izycki, Tomasz Burzykowski & Aldona Karczewska-Dzionk. (2012) Long-term survival of high-risk melanoma patients immunized with a Hyper-IL-6-modified allogeneic whole-cell vaccine after complete resection. Expert Opinion on Investigational Drugs 21:6, pages 773-783.
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P J Wysocki, J Zolnierek, C Szczylik & A Mackiewicz. (2007) Recent developments in renal cell cancer immunotherapy. Expert Opinion on Biological Therapy 7:5, pages 727-737.
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Ivan S. Pires, Paula T. Hammond & Darrell J. Irvine. (2021) Engineering Strategies for Immunomodulatory Cytokine Therapies: Challenges and Clinical Progress. Advanced Therapeutics 4:8, pages 2100035.
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Jonathan J. Duplisea, Sharada Mokkapati, Devin Plote, Kimberly S. Schluns, David J. McConkey, Seppo Yla-Herttuala, Nigel R. Parker & Colin P. Dinney. (2018) The development of interferon-based gene therapy for BCG unresponsive bladder cancer: from bench to bedside. World Journal of Urology 37:10, pages 2041-2049.
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Ewa Leporowska. (2012) Wybrane parametry laboratoryjne w monitorowaniu chorych immunizowanych genetycznie modyfikowaną szczepionką przeciwczerniakową. Zeszyty Naukowe WCO, Letters in Oncology Science 9:4, pages 183-193.
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P J Wysocki, U Kazimierczak, W Suchorska, M Kotlarski, J Malicki & A Mackiewicz. (2010) Gene-modified tumor vaccine secreting a designer cytokine Hyper-Interleukin-6 is an effective therapy in mice bearing orthotopic renal cell cancer. Cancer Gene Therapy 17:7, pages 465-475.
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Zhiming Hu, Wanlong Tan, Lin Zhang, Zhongkun Liang, Cuixiang Xu, Hua Su, Jianxin Lu & Jimin Gao. (2009) A novel immunotherapy for superficial bladder cancer by intravesical immobilization of GM-CSF. Journal of Cellular and Molecular Medicine 14:6b, pages 1836-1844.
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Tae S. Kim, Byeong C. Lee, Eugene Kim, Daeho Cho & Edward P. Cohen. (2008) Gene transfer of AIMP1 and B7.1 into epitope-loaded, fibroblasts induces tumor-specific CTL immunity, and prolongs the survival period of tumor-bearing mice. Vaccine 26:47, pages 5928-5934.
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Michela Croce, Raffaella Meazza, Anna M. Orengo, Marina Fabbi, Martina Borghi, Domenico Ribatti, Beatrice Nico, Barbara Carlini, Vito Pistoia, Maria Valeria Corrias & Silvano Ferrini. (2008) Immunotherapy of neuroblastoma by an Interleukin-21-secreting cell vaccine involves survivin as antigen. Cancer Immunology, Immunotherapy 57:11, pages 1625-1634.
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Y Shi, M Zou, E Y Baitei, A S Alzahrani, R S Parhar, Z Al-Makhalafi & F A Al-Mohanna. (2007) Cannabinoid 2 receptor induction by IL-12 and its potential as a therapeutic target for the treatment of anaplastic thyroid carcinoma. Cancer Gene Therapy 15:2, pages 101-107.
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S. A. Nedospasov & D. V. Kuprash. (2007) Oncoimmunology: Some fundamental problems of cancer immunotherapy. Molecular Biology 41:2, pages 316-328.
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Angelica Loskog, Christina Ninalga, Gabriella Paul-Wetterberg, Manuel de la Torre, Per-Uno Malmström & Thomas H. Tötterman. (2007) Human Bladder Carcinoma is Dominated by T-Regulatory Cells and Th1 Inhibitory Cytokines. The Journal of Urology 177:1, pages 353-358.
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Thomas H. Totterman, Angelica Loskog & Magnus Essand. (2005) The immunotherapy of prostate and bladder cancer. BJU International 96:5, pages 728-735.
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Ivonne van Bruggen, Delia J Nelson, Andrew J Currie, Connie Jackaman & Bruce W. S Robinson. (2005) Intratumoral Poly-N-Acetyl Glucosamine-Based Polymer Matrix Provokes a Prolonged Local Inflammatory Response That, When Combined with IL-2, Induces Regression of Malignant Mesothelioma in a Murine Model. Journal of Immunotherapy 28:4, pages 359-367.
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