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Expert Opinion on Biological Therapy Volume 5, 2005 - Issue sup1
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Review

Engineering of monoclonal antibodies and antibody-based fusion proteins: successes and challenges

Jean-Luc Teillaud University Paris 6-Pierre & Marie Curie, Unité INSERM 255, Centre de Recherches Biomédicales des Cordeliers, 15 rue de l’Ecole de Médecine, 75270 Paris Cedex 06, France. [email protected]
Pages S15-S27 | Published online: 28 Sep 2005

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Klaus Bendtzen, Mark Ainsworth, Casper Steenholdt, Ole Østergaard Thomsen & Jørn Brynskov. (2009) Individual medicine in inflammatory bowel disease: Monitoring bioavailability, pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies. Scandinavian Journal of Gastroenterology 44:7, pages 774-781.
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Lawrence G Lum & Zaid Al-Kadhimi. (2008) Development and prospects for bispecific antibody-based therapeutics in cancer and other applications. Expert Opinion on Drug Discovery 3:9, pages 1081-1097.
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Noah Joseph, Anastasia Shapiro, Ella Gillis, Shirin Barkey, Almogit Abu-Horowitz, Ido Bachelet & Boaz Mizrahi. (2023) Biodistribution and function of coupled polymer-DNA origami nanostructures. Scientific Reports 13:1.
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Jiří Vymětal, Kateřina Mertová, Kristýna Boušová, Josef Šulc, Konstantinos Tripsianes & Jiri Vondrasek. (2022) Fusion of two unrelated protein domains in a chimera protein and its 3D prediction: Justification of the x‐ray reference structures as a prediction benchmark . Proteins: Structure, Function, and Bioinformatics 90:12, pages 2067-2079.
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Julie Rousseau, Joseph Lau & François Bénard. 2022. Nuclear Medicine and Immunology. Nuclear Medicine and Immunology 297 345 .
Nguyen Xuan Vu, Natcha Pruksametanan, Witsanu Srila, Watcharin Yuttavanichakul, Kamonluck Teamtisong, Neung Teaumroong, Nantakorn Boonkerd, Panlada Tittabutr & Montarop Yamabhai. (2017) Generation of a rabbit single-chain fragment variable (scFv) antibody for specific detection of Bradyrhizobium sp. DOA9 in both free-living and bacteroid forms. PLOS ONE 12:6, pages e0179983.
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Clément Bailly, Pierre-François Cléry, Alain Faivre-Chauvet, Mickael Bourgeois, François Guérard, Ferid Haddad, Jacques Barbet, Michel Chérel, Françoise Kraeber-Bodéré, Thomas Carlier & Caroline Bodet-Milin. (2016) Immuno-PET for Clinical Theranostic Approaches. International Journal of Molecular Sciences 18:1, pages 57.
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Floriane Noël, Alain Malpertuy & Alexandre G. de Brevern. (2016) Global analysis of VHHs framework regions with a structural alphabet. Biochimie 131, pages 11-19.
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Françoise Kraeber-Bodéré, Caroline Rousseau, Caroline Bodet-Milin, Cédric Mathieu, François Guérard, Eric Frampas, Thomas Carlier, Nicolas Chouin, Ferid Haddad, Jean-François Chatal, Alain Faivre-Chauvet, Michel Chérel & Jacques Barbet. (2015) Tumor Immunotargeting Using Innovative Radionuclides. International Journal of Molecular Sciences 16:2, pages 3932-3954.
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Tanya Q. Shang, Andrew Saati, Kelly N. Toler, Jianming Mo, Heyi Li, Tonya Matlosz, Xi Lin, Jennifer Schenk, Chee‐Keng Ng, Toni Duffy, Thomas J. Porter & Jason C. Rouse. (2014) Development and Application of a Robust N‐Glycan Profiling Method for Heightened Characterization of Monoclonal Antibodies and Related Glycoproteins. Journal of Pharmaceutical Sciences 103:7, pages 1967-1978.
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Xiaoyi Yang, Abraham Kallarakal, Nirmala Saptharishi, Hengguang Jiang, Zhiwen Yang, Yueqing Xie, George Mitra, Xin Xiao Zheng, Terry B. Strom & Gopalan Soman. (2013) Molecular Characterization and Functional Activity of an IL-15 Antagonist MutIL-15/Fc Human Fusion Protein. Molecular Pharmaceutics 10:2, pages 717-727.
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Alastair H. Dent. 2013. The Immunoassay Handbook. The Immunoassay Handbook 301 313 .
Jason E. Hudak, Robyn M. Barfield, Gregory W. de Hart, Patricia Grob, Eva Nogales, Carolyn R. Bertozzi & David Rabuka. (2012) Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag. Angewandte Chemie International Edition 51:17, pages 4161-4165.
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Jason E. Hudak, Robyn M. Barfield, Gregory W. de Hart, Patricia Grob, Eva Nogales, Carolyn R. Bertozzi & David Rabuka. (2012) Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag. Angewandte Chemie 124:17, pages 4237-4241.
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Jacques Barbet, Manuel Bardiès, Mickael Bourgeois, Jean-François Chatal, Michel Chérel, François Davodeau, Alain Faivre-Chauvet, Jean-François Gestin & Françoise Kraeber-Bodéré. 2012. Antibody Engineering. Antibody Engineering 681 697 .
Klaus Bendtzen & Morten Svenson. 2011. Detection and Quantification of Antibodies to Biopharmaceuticals. Detection and Quantification of Antibodies to Biopharmaceuticals 81 101 .
Jonas L. Fast, Amanda A. Cordes, John F. CarpenterTheodore W. Randolph. (2009) Physical Instability of a Therapeutic Fc Fusion Protein: Domain Contributions to Conformational and Colloidal Stability. Biochemistry 48:49, pages 11724-11736.
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Riad Abès, Charles-Antoine Dutertre & Jean-Luc Teillaud. (2009) Les anticorps : mieux les connaître pour mieux s’en servir. médecine/sciences 25:12, pages 1011-1019.
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Robert O. Dillman. 2009. Principles of Cancer Biotherapy. Principles of Cancer Biotherapy 303 406 .
David E. Steinmeyer & Ellen L. McCormick. (2008) The art of antibody process development. Drug Discovery Today 13:13-14, pages 613-618.
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Roland Beliard, Tony Waegemans, Dominique Notelet, Léna Massad, Frédéric Dhainaut, Christophe de Romeuf, Eric Guemas, Wouter Haazen, Dominique Bourel, Jean-Luc Teillaud & Jean-François Prost. (2008) A human anti-D monoclonal antibody selected for enhanced FcγRIII engagement clears RhD + autologous red cells in human volunteers as efficiently as polyclonal anti-D antibodies . British Journal of Haematology 141:1, pages 109-119.
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Klaus Bendtzen. 2008. Immunogenicity of Biopharmaceuticals. Immunogenicity of Biopharmaceuticals 189 203 .
Jean Sibilia. (2007) Naissance et développement de l’immunothérapie ciblée : La révolution des biomédicaments. Revue du Rhumatisme 74, pages 42-51.
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Ana C.A. Roque, Cláudia S.O. Silva & M. Ângela Taipa. (2007) Affinity-based methodologies and ligands for antibody purification: Advances and perspectives. Journal of Chromatography A 1160:1-2, pages 44-55.
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Jean Sibilia. (2006) Les bioth?rapies immunomodulatrices: Une r?volution th?rapeutique dans les maladies auto-immunes. Revue Francophone des Laboratoires 2006:384, pages 34-39.
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Jean Sibilia. (2006) Bioth?rapies: ?volution ou r?volution?. La Presse M?dicale 35:4, pages 637-640.
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