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Expert Opinion on Biological Therapy Volume 5, 2005 - Issue sup1
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Review

From cellular receptors to transduction–transcription pathways for cytokines: at which level should the inhibition be targeted in inflammation?

Jean-Michel Dayer University Hospital & Faculty of Medicine, Service of Immunology & Allergy, 24, Rue Micheli-du-Crest, 1211 Geneva 14, Switzerland. [email protected]
,
Nicolas Molnarfi University Hospital & Faculty of Medicine, Service of Immunology & Allergy, 24, Rue Micheli-du-Crest, 1211 Geneva 14, Switzerland. [email protected]
&
Danielle Burger University Hospital & Faculty of Medicine, Service of Immunology & Allergy, 24, Rue Micheli-du-Crest, 1211 Geneva 14, Switzerland. [email protected]
Pages S83-S96 | Published online: 24 Nov 2005

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Alessandra Musella, Diego Fresegna, Francesca Romana Rizzo, Antonietta Gentile, Francesca De Vito, Silvia Caioli, Livia Guadalupi, Antonio Bruno, Ettore Dolcetti, Fabio Buttari, Silvia Bullitta, Valentina Vanni, Diego Centonze & Georgia Mandolesi. (2020) ‘Prototypical’ proinflammatory cytokine (IL-1) in multiple sclerosis: role in pathogenesis and therapeutic targeting. Expert Opinion on Therapeutic Targets 24:1, pages 37-46.
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Francis J Dumont. (2006) The interleukin-1 families of cytokines and receptors: therapeutic potential for immunomodulation and the treatment of inflammatory disorders. Expert Opinion on Therapeutic Patents 16:7, pages 879-912.
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Articles from other publishers (6)

Takeshi Tomita, Katsuaki Ieguchi, Fredric Coin, Yasuhiro Kato, Haruhisa Kikuchi, Yoshiteru Oshima, Shoichiro Kurata & Yoshiro Maru. (2014) ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor. PLoS ONE 9:9, pages e108957.
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Úrsula Catalán, Sara Fernández-Castillejo, Neus Anglès, Jose Ramón Morelló, Martí Yebras & Rosa Solà. (2012) Inhibition of the transcription factor c-Jun by the MAPK family, and not the NF-κB pathway, suggests that peanut extract has anti-inflammatory properties. Molecular Immunology 52:3-4, pages 125-132.
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Lars Olaf Cardell, Rolf Uddman, Yaping Zhang & Mikael Adner. (2008) Interleukin-1β up-regulates tumor necrosis factor receptors in the mouse airways. Pulmonary Pharmacology & Therapeutics 21:4, pages 675-681.
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Rebecca K. Studer, Lars G. Gilbertson, Helga Georgescu, Gwendolyn Sowa, Nam Vo & James D. Kang. (2008) p38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL‐1. Journal of Orthopaedic Research 26:7, pages 991-998.
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Maria Schäfers & Linda Sorkin. (2008) Effect of cytokines on neuronal excitability. Neuroscience Letters 437:3, pages 188-193.
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Li Sun, Jameel Iqbal, Samir Zaidi, Ling-Ling Zhu, Xuefeng Zhang, Yuanzheng Peng, Baljit S. Moonga & Mone Zaidi. (2006) Structure and functional regulation of the CD38 promoter. Biochemical and Biophysical Research Communications 341:3, pages 804-809.
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