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Review

Treatment of neurodegenerative diseases using adult bone marrow stromal cell-derived neurons

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Pages 427-435 | Published online: 22 Apr 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Alireza Abdanipour, Taki Tiraihi & Javad Mirnajafi-Zadeh. (2011) Improvement of the pilocarpine epilepsy model in rat using bone marrow stromal cell therapy. Neurological Research 33:6, pages 625-632.
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Andreas Hermann, Martina Maisel & Alexander Storch. (2006) Epigenetic conversion of human adult bone mesodermal stromal cells into neuroectodermal cell types for replacement therapy of neurodegenerative disorders. Expert Opinion on Biological Therapy 6:7, pages 653-670.
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Jakob Reiser, Xian-Yang Zhang, Charles S Hemenway, Debasis Mondal, Leena Pradhan & Vincent F La Russa. (2005) Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases. Expert Opinion on Biological Therapy 5:12, pages 1571-1584.
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Articles from other publishers (23)

Hyun-Jee Kim, Sungho Shin, Seon-Yeong Jeong, Sun-Ung Lim, Dae-Won Lee, Yunhee-Kim Kwon, Jiyeon Kang, Sung-Won Kim, Chan-Kwon Jung, Cheolju Lee & Il-Hoan Oh. (2021) Nasal Turbinate Mesenchymal Stromal Cells Preserve Characteristics of Their Neural Crest Origin and Exert Distinct Paracrine Activity. Journal of Clinical Medicine 10:8, pages 1792.
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Cassandra Thompson, Paulina Otero, Bhairavi Srinageshwar, Robert B Petersen, Gary L Dunbar & Julien Rossignol. (2020) Possible roles of epigenetics in stem cell therapy for Parkinson’s disease. Epigenomics 12:7, pages 647-656.
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Marina Devetzi, Maria Goulielmaki, Nicolas Khoury, Demetrios Spandidos, Georgia Sotiropoulou, Ioannis Christodoulou & Vassilis Zoumpourlis. (2018) Genetically‑modified stem cells in treatment of human diseases: Tissue kallikrein (KLK1)‑based targeted therapy (Review). International Journal of Molecular Medicine.
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Jung-Hyun Park, Ki-Joo Kim, Jong Won Rhie & Il-Hoan Oh. (2016) Characterization of adipose tissue mesenchymal stromal cell subsets with distinct plastic adherence. Tissue Engineering and Regenerative Medicine 13:1, pages 39-46.
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Paulina Borkowska, Joanna Kowalska, Anna Fila-Danilow, Anna Maria Bielecka, Monika Paul-Samojedny, Malgorzata Kowalczyk & Jan Kowalski. (2015) Affect of antidepressants on the in vitro differentiation of rat bone marrow mesenchymal stem cells into neuronal cells. European Journal of Pharmaceutical Sciences 73, pages 81-87.
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M R Moniri, L-J Dai & G L Warnock. (2014) The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells. Cancer Gene Therapy 21:1, pages 12-23.
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Defeng Li, Xizhen Wang, Qinyan Xu, Yingying Zhang, Xihe Su, Peng Dong, Yue Guan, Guanghui Chang, Yanming Ge & Wenyu Fu. (2013) Evaluation of the therapeutic effects of mesenchymal stem cell transplantation in rat model of Parkinson's disease using 1.5T MRS. Evaluation of the therapeutic effects of mesenchymal stem cell transplantation in rat model of Parkinson's disease using 1.5T MRS.
In-Ho Park, Kwang-Ho Kim, Hyun-Kyung Choi, Jae-Seung Shim, Soo-Young Whang, Sang June Hahn, Oh-Joo Kwon & Il-Hoan Oh. (2013) Constitutive stabilization of hypoxia-inducible factor alpha selectively promotes the self-renewal of mesenchymal progenitors and maintains mesenchymal stromal cells in an undifferentiated state. Experimental & Molecular Medicine 45:9, pages e44-e44.
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Chengbin Xue, Nan Hu, Yun Gu, Yumin Yang, Yan Liu, Jie Liu, Fei Ding & Xiaosong Gu. (2011) Joint Use of a Chitosan/PLGA Scaffold and MSCs to Bridge an Extra Large Gap in Dog Sciatic Nerve. Neurorehabilitation and Neural Repair 26:1, pages 96-106.
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C V Borlongan. (2011) Bone marrow stem cell mobilization in stroke: a ‘bonehead’ may be good after all!. Leukemia 25:11, pages 1674-1686.
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Cesar V. Borlongan, Loren E. Glover, Naoki Tajiri, Yuji Kaneko & Thomas B. Freeman. (2011) The great migration of bone marrow-derived stem cells toward the ischemic brain: Therapeutic implications for stroke and other neurological disorders. Progress in Neurobiology 95:2, pages 213-228.
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Michelle Griffin, Syed Amir Iqbal, Anil Sebastian, James Colthurst & Ardeshir Bayat. (2011) Degenerate Wave and Capacitive Coupling Increase Human MSC Invasion and Proliferation While Reducing Cytotoxicity in an In Vitro Wound Healing Model. PLoS ONE 6:8, pages e23404.
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Long-Jun Dai, Mani R. Moniri, Zhi-Rong Zeng, Jeff X. Zhou, Jarrett Rayat & Garth L. Warnock. (2011) Potential implications of mesenchymal stem cells in cancer therapy. Cancer Letters 305:1, pages 8-20.
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Christopher CramerEva FreisingerRyan K. JonesDouglas P. SlakeyCharles L. DupinEdward R. NewsomeEckhard U. AltReza Izadpanah. (2010) Persistent High Glucose Concentrations Alter the Regenerative Potential of Mesenchymal Stem Cells. Stem Cells and Development 19:12, pages 1875-1884.
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Lidia Cova, Marie-Therese Armentero, Eleonora Zennaro, Cinzia Calzarossa, Patrizia Bossolasco, Giuseppe Busca, Giorgio Lambertenghi Deliliers, Elio Polli, Giuseppe Nappi, Vincenzo Silani & Fabio Blandini. (2010) Multiple neurogenic and neurorescue effects of human mesenchymal stem cell after transplantation in an experimental model of Parkinson's disease. Brain Research 1311, pages 12-27.
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Jooyoung JungNoory MoonJi-Yeon AhnEun-Jee OhMyungshin KimChul-Soo ChoJong-Chul ShinIl-Hoan Oh. (2009) Mesenchymal Stromal Cells Expanded in Human Allogenic Cord Blood Serum Display Higher Self-Renewal and Enhanced Osteogenic Potential. Stem Cells and Development 18:4, pages 559-572.
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Arshak R. AlexanianDennis J. MaimanShekar N. KurpadThomas A. Gennarelli. (2008) In Vitro and In Vivo Characterization of Neurally Modified Mesenchymal Stem Cells Induced by Epigenetic Modifiers and Neural Stem Cell Environment. Stem Cells and Development 17:6, pages 1123-1130.
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Yuka Takakura, Naohiro Yamaguchi, Takehiro Nakagaki, Katsuya Satoh, Jun-ichi Kira & Noriyuki Nishida. (2008) Bone marrow stroma cells are susceptible to prion infection. Biochemical and Biophysical Research Communications 377:3, pages 957-961.
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Gemma E. RooneyCathal MoranSiobhan S. McMahonThomas RitterMartin MaenzAlexander FlügelPeter DockeryTimothy O'BrienLinda HowardAnthony J. WindebankFrank P. Barry. (2008) Gene-Modified Mesenchymal Stem Cells Express Functionally Active Nerve Growth Factor on an Engineered Poly Lactic Glycolic Acid (PLGA) Substrate. Tissue Engineering Part A 14:5, pages 681-690.
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Yin Xia Chao, Bei Ping He, Qiong Cao & Samuel Sam Wah Tay. (2007) Protein aggregate-containing neuron-like cells are differentiated from bone marrow mesenchymal stem cells from mice with neurofilament light subunit gene deficiency. Neuroscience Letters 417:3, pages 240-245.
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Sadia Sharif, Takayuki Nakagawa, Tsunehisa Ohno, Masahiro Matsumoto, Tomoko Kita, Sheikh Riazuddin & Juichi Ito. (2007) The potential use of bone marrow stromal cells for cochlear cell therapy. NeuroReport 18:4, pages 351-354.
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Yamei Tang, Takao Yasuhara, Koichi Hara, Noriyuki Matsukawa, Mina Maki, Guolong Yu, Lin Xu, David C. Hess & Cesario V. Borlongan. (2017) Transplantation of Bone Marrow-Derived Stem Cells: A Promising Therapy for Stroke. Cell Transplantation 16:2, pages 159-169.
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Hiroaki Kamishina, Jie Deng, Takashi Oji, Jennifer A. Cheeseman & Roger M. Clemmons. (2006) Expression of neural markers on bone marrow–derived canine mesenchymal stem cells. American Journal of Veterinary Research 67:11, pages 1921-1928.
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