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Review

Clinical application of human CD4+CD25+ regulatory Tcells for the treatment of inflammatory bowel diseases

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Pages 451-462 | Published online: 22 Apr 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Tomotaka Tanaka, Takayuki Yamamoto, Koji Sawada & Rodolfo Sacco. (2017) Treatment options for children and adolescents with inflammatory bowel disease: is granulomonocytapheresis an effective alternative to drug therapy?. Expert Review of Gastroenterology & Hepatology 11:8, pages 749-758.
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Sergio Rutella, Silvio Danese & Giuseppe Leone. (2005) Regulatory T cells for immunotherapy of autoimmune diseases: from the bench to the bedside. Expert Opinion on Therapeutic Patents 15:11, pages 1595-1616.
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Articles from other publishers (24)

Wenyan Gao, Yufang Guo, Changhong Wang, Yifan Lin, Li Yu, Tianjiao Sheng, Zhuolin Wu & Yang Gong. (2016) Indirubin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice through the inhibition of inflammation and the induction of Foxp3-expressing regulatory T cells. Acta Histochemica 118:6, pages 606-614.
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Takahiro Hiratsuka, Masafumi Inomata, Shigeru Goto, Yoshimasa Oyama, Toshiaki Nakano, Chao-Long Chen, Norio Shiraishi, Takayuki Noguchi & Seigo Kitano. (2014) Phototherapy with artificial light suppresses dextran sulfate sodium-induced colitis in a mouse model. Journal of Gastroenterology and Hepatology 29:4, pages 749-756.
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Abbi R Saniabadi. (2014) Treating inflammatory bowel disease by adsorptive leucocytapheresis: A desire to treat without drugs. World Journal of Gastroenterology 20:29, pages 9699.
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Yohei Okada, Noriaki Maeda, Shoji Takakura, Keiji Miyata & Masahiro Koshiba. (2011) Preventive and therapeutic effects of tacrolimus in an interleukin-10-deficient mouse model of colitis. Inflammation Research 60:11, pages 1049-1059.
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Asa Hakansson & Goran Molin. (2011) Gut Microbiota and Inflammation. Nutrients 3:6, pages 637-682.
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Tomotaka Tanaka, Hideharu Okanobu, Yoshio Kuga, Yoshikazu Yoshifuku, Hatsue Fujino, Tomohiro Miwata, Takashi Moriya, Toshihiro Nishida & Toshihide Oya. (2010) Clinical and endoscopic features of responders and non-responders to adsorptive leucocytapheresis: A report based on 120 patients with active ulcerative colitis. Gastroentérologie Clinique et Biologique 34:12, pages 687-695.
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Yoshiyuki Ueno, Yoko M Ambrosini, Yuki Moritoki, William M Ridgway & M Eric Gershwin. (2010) Murine models of autoimmune cholangitis. Current Opinion in Gastroenterology 26:3, pages 274-279.
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Ching Y. Voss, Terry J. Fry, Max J. Coppes & Morris A. Blajchman. (2010) Extending the Horizon for Cell-Based Immunotherapy by Understanding the Mechanisms of Action of Photopheresis. Transfusion Medicine Reviews 24:1, pages 22-32.
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Fumie Jimma, Yuji Takeda, Kenta Kaneda & Ichiro Wakabayashi. (2010) Induction of Foxp3 expression in T cells by cellulose acetate beads in vitro. Journal of Clinical Apheresis 25:4, pages 216-222.
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Takanori Kanai, Yasuhiro Nemoto, Nobuhiko Kamada, Teruji Totsuka, Tadakazu Hisamatsu, Mamoru Watanabe & Toshifumi Hibi. (2009) Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease. Current Opinion in Gastroenterology 25:4, pages 306-313.
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K Kamikozuru, K Fukunaga, S Hirota, N Hida, Y Ohda, K Yoshida, Y Yokoyama, K Tozawa, K Kawa, M Iimuro, K Nagase, A R Saniabadi, S Nakamura, H Miwa & T Matsumoto. (2009) The expression profile of functional regulatory T cells, CD4+CD25high+/forkhead box protein P3+, in patients with ulcerative colitis during active and quiescent disease. Clinical and Experimental Immunology 156:2, pages 320-327.
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Katrina K. Hoyer, Wilson F. Kuswanto, Eugenio Gallo & Abul K. Abbas. (2009) Distinct roles of helper T-cell subsets in a systemic autoimmune disease. Blood 113:2, pages 389-395.
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Willy Hsu, Weici Zhang, Koichi Tsuneyama, Yuki Moritoki, William M. Ridgway, Aftab A. Ansari, Ross L. Coppel, Zhe-Xiong Lian, Ian Mackay & M. Eric Gershwin. (2009) Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Rα−/− mice. Hepatology 49:1, pages 133-140.
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Katrina K. Hoyer, Hans Dooms, Luke Barron & Abul K. Abbas. (2008) Interleukin-2 in the development and control of inflammatory disease. Immunological Reviews 226:1, pages 19-28.
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T. Tanaka, H. Okanobu, S. Yoshimi, E. Murakami, A. Kogame, H. Imagawa, Y. Numata, Y. Kuga, T. Moriya, T. Ohya & G. Kajiyama. (2008) In patients with ulcerative colitis, adsorptive depletion of granulocytes and monocytes impacts mucosal level of neutrophils and clinically is most effective in steroid naïve patients. Digestive and Liver Disease 40:9, pages 731-736.
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Douglas J. Begg & Richard J. Whittington. (2008) Experimental animal infection models for Johne’s disease, an infectious enteropathy caused by Mycobacterium avium subsp. paratuberculosis. The Veterinary Journal 176:2, pages 129-145.
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Susana Lopes-da-Silva & Luiz Vicente Rizzo. (2008) Autoimmunity in Common Variable Immunodeficiency. Journal of Clinical Immunology 28:S1, pages 46-55.
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Abbi R. Saniabadi, Hiroyuki Hanai, Ken Fukunaga, Koji Sawada, Chikako Shima, Ingvar Bjarnason & Robert Lofberg. (2007) Therapeutic leukocytapheresis for inflammatory bowel disease. Transfusion and Apheresis Science 37:2, pages 191-200.
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Yoko Yokoyama, Ken Fukunaga, Yoshihiro Fukuda, Katsuyuki Tozawa, Koji Kamikozuru, Kunio Ohnishi, Takeshi Kusaka, Tadashi Kosaka, Nobuyuki Hida, Yoshio Ohda, Hiroto Miwa & Takayuki Matsumoto. (2007) Demonstration of Low-Regulatory CD25High+CD4+ and High-Pro-inflammatory CD28−CD4+ T-Cell Subsets in Patients with Ulcerative Colitis: Modified by Selective Granulocyte and Monocyte Adsorption Apheresis. Digestive Diseases and Sciences 52:10, pages 2725-2731.
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N Shiobara, Y Suzuki, H Aoki, A Gotoh, Y Fujii, Y Hamada, S Suzuki, N Fukui, I Kurane, T Itoh & R Suzuki. (2007) Bacterial superantigens and T cell receptor β-chain-bearing T cells in the immunopathogenesis of ulcerative colitis. Clinical and Experimental Immunology 150:1, pages 13-21.
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Hiroshi Aoki, Kentaro Nakamura, Yasushi Yoshimatsu, Yukiko Tsuda, Masaki Irie, Katsuyuki Fukuda, Nobuo Hosoe, Nobuo Takada, Koji Shirai & Yasuo Suzuki. (2007) Adacolumn Selective Leukocyte Adsorption Apheresis in Patients with Active Ulcerative Colitis: Clinical Efficacy, Effects on Plasma IL-8, and Expression of Toll-like Receptor 2 on Granulocytes. Digestive Diseases and Sciences 52:6, pages 1427-1433.
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C. EVANS, A. G. DALGLEISH & D. KUMAR. (2006) Review article: immune suppression and colorectal cancer. Alimentary Pharmacology and Therapeutics 24:8, pages 1163-1177.
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Hiroyuki Hanai. (2006) Positions of selective leukocytapheresis in the medical therapy of ulcerative colitis. World Journal of Gastroenterology 12:47, pages 7568.
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Ping-Chang Yang, Tao Liu, Bin-Quan Wang, Tao-Yuan Zhang, Zi-Yuan An, Peng-Yuan Zheng & Dao-Fa Tian. (2005) Rhinosinusitis derived Staphylococcal enterotoxin B possibly associates with pathogenesis of ulcerative colitis. BMC Gastroenterology 5:1.
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