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Review

Synthetic antibodies as therapeutics

Pages 73-87 | Published online: 06 Dec 2006

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Arvind Sivasubramanian, Patricia Estep, Heather Lynaugh, Yao Yu, Adam Miles, Josh Eckman, Kevin Schutz, Crystal Piffath, Nadthakarn Boland, Rebecca Hurley Niles, Stéphanie Durand, Todd Boland, Maximiliano Vásquez, Yingda Xu & Yasmina Abdiche. (2017) Broad epitope coverage of a human in vitro antibody library. mAbs 9:1, pages 29-42.
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Dmitri Dormeshkin, Michail Shapira, Simon Dubovik, Anton Kavaleuski, Mikalai Katsin, Alexandr Migas, Alexander Meleshko & Sergei Semyonov. (2022) Isolation of an escape-resistant SARS-CoV-2 neutralizing nanobody from a novel synthetic nanobody library. Frontiers in Immunology 13.
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Jane Zveiter de Moraes, Barbara Hamaguchi, Camila Braggion, Enzo Speciale, Fernanda Cesar, Gabriela Soares, Juliana Osaki, Rodrigo Aguiar & Tauane Pereira. 2021. Monoclonal Antibodies. Monoclonal Antibodies.
Jane Zveiter Moraes, Bárbara Hamaguchi, Camila Braggion, Enzo Reina Speciale, Fernanda Beatriz Viana Cesar, Gabriela de Fátima da Silva Soares, Juliana Harumi Osaki, Tauane Mathias Pereira & Rodrigo Barbosa Aguiar. (2021) Hybridoma technology: is it still useful?. Current Research in Immunology 2, pages 32-40.
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Rolando Paciello, Richard A. Urbanowicz, Gennaro Riccio, Emanuele Sasso, C. Patrick McClure, Nicola Zambrano, Jonathan K. Ball, Riccardo Cortese, Alfredo Nicosia & Claudia De Lorenzo. (2016) Novel human anti-claudin 1 mAbs inhibit hepatitis C virus infection and may synergize with anti-SRB1 mAb. Journal of General Virology 97:1, pages 82-94.
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Ciara M. Mahon, Matthew A. Lambert, Jacob Glanville, Jason M. Wade, Brian J. Fennell, Mark R. Krebs, Douglas Armellino, Sharon Yang, Xuemei Liu, Cliona M. O'Sullivan, Benedicte Autin, Katarzyna Oficjalska, Laird Bloom, Janet Paulsen, Davinder Gill, Marc Damelin, Orla Cunningham & William J.J. Finlay. (2013) Comprehensive Interrogation of a Minimalist Synthetic CDR-H3 Library and Its Ability to Generate Antibodies with Therapeutic Potential. Journal of Molecular Biology 425:10, pages 1712-1730.
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Krzysztof Lacek, Koen Vercauteren, Katarzyna Grzyb, Mariarosaria Naddeo, Lieven Verhoye, Marek Patryk Słowikowski, Samira Fafi-Kremer, Arvind H. Patel, Thomas F. Baumert, Antonella Folgori, Geert Leroux-Roels, Riccardo Cortese, Philip Meuleman & Alfredo Nicosia. (2012) Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice. Journal of Hepatology 57:1, pages 17-23.
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Leeying Wu, Katarzyna Oficjalska, Matthew Lambert, Brian J. Fennell, Alfredo Darmanin-Sheehan, Deirdre Ní Shúilleabháin, Bénédicte Autin, Emma Cummins, Lioudmila Tchistiakova, Laird Bloom, Janet Paulsen, Davinder Gill, Orla Cunningham & William J. J. Finlay. (2012) Fundamental Characteristics of the Immunoglobulin VH Repertoire of Chickens in Comparison with Those of Humans, Mice, and Camelids. The Journal of Immunology 188:1, pages 322-333.
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Vered Bronner, Galit Denkberg, Mira Peled, Yael Elbaz, Efrat Zahavi, Harel Kasoto, Yoram Reiter, Ariel Notcovich & Tsafrir Bravman. (2010) Therapeutic antibodies: Discovery and development using the ProteOn XPR36 biosensor interaction array system. Analytical Biochemistry 406:2, pages 147-156.
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Edward Htun van der Horst, Lawrence Chinn, Min Wang, Timothy Velilla, Hoang Tran, Yarrow Madrona, Andrew Lam, May Ji, Timothy C. Hoey & Aaron K. Sato. (2009) Discovery of Fully Human Anti-MET Monoclonal Antibodies with Antitumor Activity against Colon Cancer Tumor Models In Vivo. Neoplasia 11:4, pages 355-IN5.
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Ralf J. Hosse, Leigh Tay, Meghan K. Hattarki, Luisa Pontes-Braz, Lesley A. Pearce, Stewart D. Nuttall & Olan Dolezal. (2009) Kinetic screening of antibody–Im7 conjugates by capture on a colicin E7 DNase domain using optical biosensors. Analytical Biochemistry 385:2, pages 346-357.
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David R. Buckler, Albert Park, Malini Viswanathan, Rene M. Hoet & Robert C. Ladner. (2008) Screening isolates from antibody phage-display libraries. Drug Discovery Today 13:7-8, pages 318-324.
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Paolo Monaci, Alessandra Luzzago, Claudia Santini, Alessandra De Pra, Mirko Arcuri, Francesca Magistri, Alessandro Bellini, Helenia Ansuini, Maria Ambrosio, Virginia Ammendola, Maria Giulia Bigotti, Agostino Cirillo, Maurizio Nuzzo, Annamaria Assunta Nasti, Philippe Neuner, Laura Orsatti, Monica Pezzanera, Andrea Sbardellati, Giuseppe Silvestre, Paolo Uva, Valentina Viti, Gaetano Barbato, Stefano Colloca, Anna Demartis, Emanuele De Rinaldis, Saverio Giampaoli, Armin Lahm, Fabio Palombo, Fabio Talamo, Alessandra Vitelli, Alfredo Nicosia & Riccardo Cortese. (2008) Differential Screening of Phage-Ab Libraries by Oligonucleotide Microarray Technology. PLoS ONE 3:1, pages e1508.
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Karl Ziegelbauer & David R Light. (2007) Monoclonal antibody therapeutics: Leading companies to maximise sales and market share. Journal of Commercial Biotechnology 14:1, pages 65-72.
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