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Expert Opinion on Biological Therapy Volume 7, 2007 - Issue 10
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Review

Adjuvants in vaccines and for immunisation: current trends

Pieranna Chiarella University ‘Campus Bio-Medico of Rome’, Laboratory of Molecular Medicine and Biotechnology, School of Medicine, Rome, Italy; Bio-Ker s.r.l., Pula (CA), Italy
,
Emanuela Massi University ‘Campus Bio-Medico of Rome’, Laboratory of Molecular Medicine and Biotechnology, School of Medicine, Rome, Italy
,
Mariangela De Robertis University ‘Campus Bio-Medico of Rome’, Laboratory of Molecular Medicine and Biotechnology, School of Medicine, Rome, Italy
,
Emanuela Signori Institute of Neurobiology and Molecular Medicine, CNR, Area Ricerca Tor Vergata, Via Fosso del Cavaliere 100, 00133 Rome, Italy + 39 0649934232; + 39 0649934257; [email protected]
&
Vito Michele Fazio University ‘Campus Bio-Medico of Rome’, Laboratory of Molecular Medicine and Biotechnology, School of Medicine, Rome, Italy; Laboratory of Oncology, IRCCS H. ‘Casa Sollievo della Sofferenza’, San Giovanni Rotondo (FG), Italy
Pages 1551-1562 | Published online: 05 Oct 2007

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Ruhi V. Ubale, Martin J. D'souza, Daniel T. Infield, Nael A. McCarty & Susu M. Zughaier. (2013) Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition. Journal of Microencapsulation 30:1, pages 28-41.
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Raquel Da Costa Martins, Juan M Irache & Carlos Gamazo. (2012) Acellular vaccines for ovine brucellosis: a safer alternative against a worldwide disease. Expert Review of Vaccines 11:1, pages 87-95.
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Pieranna Chiarella, Emanuela Massi, Mariangela De Robertis, Annarita Sibilio, Paola Parrella, Vito Michele Fazio & Emanuela Signori. (2008) Electroporation of skeletal muscle induces danger signal release and antigen-presenting cell recruitment independently of DNA vaccine administration. Expert Opinion on Biological Therapy 8:11, pages 1645-1657.
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Articles from other publishers (20)

Qian Li, Ashenafi Kiros Wubshet, Yang Wang, Livio Heath & Jie Zhang. (2023) B and T Cell Epitopes of the Incursionary Foot-and-Mouth Disease Virus Serotype SAT2 for Vaccine Development. Viruses 15:3, pages 797.
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Matej Kranjc, Simona Kranjc Brezar, Gregor Serša & Damijan Miklavčič. (2021) Contactless delivery of plasmid encoding EGFP in vivo by high-intensity pulsed electromagnetic field. Bioelectrochemistry 141, pages 107847.
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Abate Assefa Bashaw, Siok M. Teoh, Zewen K. Tuong, Graham R. Leggatt, Ian H. Frazer & Janin Chandra. (2019) HPV16 E7-Driven Epithelial Hyperplasia Promotes Impaired Antigen Presentation and Regulatory T-Cell Development. Journal of Investigative Dermatology 139:12, pages 2467-2476.e3.
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Frank Blanco-Pérez, Garibald Papp, Alexandra Goretzki, Tobias Möller, Martina Anzaghe & Stefan Schülke. (2019) Adjuvant Allergen Fusion Proteins as Novel Tools for the Treatment of Type I Allergies. Archivum Immunologiae et Therapiae Experimentalis 67:5, pages 273-293.
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Rikhav P. Gala, Martin D'Souza & Susu M. Zughaier. (2016) Evaluation of various adjuvant nanoparticulate formulations for meningococcal capsular polysaccharide-based vaccine. Vaccine 34:28, pages 3260-3267.
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Rikhav Gala, Ruhi Ubale, Martin D'Souza & Susu Zughaier. 2015. Nanoparticulate Vaccine Delivery Systems. Nanoparticulate Vaccine Delivery Systems 127 140 .
Grzegorz Kijanka, Melody Sauerborn, Louis Boon, Huub Schellekens & Vera Brinks. (2015) Development of ADA Against Recombinant Human Interferon Beta in Immune Tolerant Mice Requires Rapid Recruitment of CD4+ T Cells, Induces Formation of Germinal Centers but Lacks Susceptibility for (Most) Adjuvants. Journal of Pharmaceutical Sciences 104:2, pages 396-406.
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Mallesh Beesu, Subbalakshmi S. Malladi, Lauren M. Fox, Cassandra D. Jones, Anshuman Dixit & Sunil A. David. (2014) Human Toll-Like Receptor 8-Selective Agonistic Activities in 1-Alkyl-1 H -benzimidazol-2-amines . Journal of Medicinal Chemistry 57:17, pages 7325-7341.
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Huimin Yang, Shuying Han, Danyang Zhao & Guiyun Wang. (2014) Adjuvant effect of polysaccharide from fruits of Physalis alkekengi L. in DNA vaccine against systemic candidiasis. Carbohydrate Polymers 109, pages 77-84.
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A. V. Pronin, S. V. Ozherelkov, A. V. Deyeva, A. V. Sanin & A. N. Narovljansky. (2014) POLYPRENYL PHOSPHATES AS ADJUVANTS, POLARIZING THE IMMUNE RESPONSE TO Th1. Russian Journal of Infection and Immunity 2:3, pages 645-650.
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Pieranna Chiarella & Emanuela Signori. 2014. Electroporation Protocols. Electroporation Protocols 315 324 .
Pieranna ChiarellaStefania De SantisVito M. FazioEmanuela Signori. (2013) Hyaluronidase Contributes to Early Inflammatory Events Induced by Electrotransfer in Mouse Skeletal Muscle. Human Gene Therapy 24:4, pages 406-416.
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L. Salleras. (2012) Adyuvantes potentes y seguros: una necesidad para las nuevas vacunas antigripales. Vacunas 13:2, pages 47-48.
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Emanuela Signori, Sandra Iurescia, Emanuela Massi, Daniela Fioretti, Pieranna Chiarella, Mariangela De Robertis, Monica Rinaldi, Giancarlo Tonon & Vito Michele Fazio. (2010) DNA vaccination strategies for anti-tumour effective gene therapy protocols. Cancer Immunology, Immunotherapy 59:10, pages 1583-1591.
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Pieranna Chiarella, Bärbel Edelmann, Vito M. Fazio, Alan M. Sawyer & Ario de Marco. (2010) Antigenic features of protein carriers commonly used in immunisation trials. Biotechnology Letters 32:9, pages 1215-1221.
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. (2010) Scientific Opinion on the assessment of allergenicity of GM plants and microorganisms and derived food and feed. EFSA Journal 8:7, pages 1700.
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Adam M. Farkas & Olivera J. Finn. (2010) Vaccines based on abnormal self-antigens as tumor-associated antigens: Immune regulation. Seminars in Immunology 22:3, pages 125-131.
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Alessia Fabbri, Sara Travaglione & Carla Fiorentini. (2010) Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1): Toxin Biology, in Vivo Applications and Therapeutic Potential. Toxins 2:2, pages 283-296.
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Kaustabh K. Maiti, Michael DeCastro, Abu-Baker M. Abdel-Aal El-Sayed, Matthew I. Foote, Margreet A. Wolfert & Geert-Jan Boons. (2010) Chemical Synthesis and Proinflammatory Responses of Monophosphoryl Lipid A Adjuvant Candidates. European Journal of Organic Chemistry 2010:1, pages 80-91.
Crossref
Kim S. Jones. (2008) Biomaterials as vaccine adjuvants. Biotechnology Progress 24:4, pages 807-814.
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