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New peptide nucleic acid analogues: synthesis and applications

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Pages 1219-1232 | Published online: 14 Aug 2007

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Mallikarjunachari V. N. Uppuladinne, Uddhavesh B. Sonavane, Ramesh Ch. Deka & Rajendra R. Joshi. (2019) Structural insight into antisense gapmer-RNA oligomer duplexes through molecular dynamics simulations. Journal of Biomolecular Structure and Dynamics 37:11, pages 2823-2836.
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Maria Moccia, Mauro F A Adamo & Michele Saviano. (2014) Insights on chiral, backbone modified peptide nucleic acids: Properties and biological activity. Artificial DNA: PNA & XNA 5:3.
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Articles from other publishers (19)

Andrea Mosseri, Maria Sancho‐Albero, Marilisa Leone, Donatella Nava, Francesco Secundo, Daniela Maggioni, Luisa De Cola & Alessandra Romanelli. (2022) Chiral Fibers Formation Upon Assembly of Tetraphenylalanine Peptide Conjugated to a PNA Dimer. Chemistry – A European Journal 28:37.
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Mallikarjunachari V.N. Uppuladinne, Dikshita Dowerah, Uddhavesh B. Sonavane, Suvendra Kumar Ray, Ramesh C. Deka & Rajendra R. Joshi. (2021) Structural insight into locked nucleic acid based novel antisense modifications: A DFT calculations at monomer and MD simulations at oligomer level. Journal of Molecular Graphics and Modelling 107, pages 107945.
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Paola Ringhieri, Concetta Avitabile, Michele Saviano, Giancarlo Morelli, Alessandra Romanelli & Antonella Accardo. (2016) The influence of liposomal formulation on the incorporation and retention of PNA oligomers. Colloids and Surfaces B: Biointerfaces 145, pages 462-469.
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Concetta Avitabile, Antonella Accardo, Paola Ringhieri, Giancarlo Morelli, Michele Saviano, Giulia Montagner, Enrica Fabbri, Eleonora Gallerani, Roberto Gambari & Alessandra Romanelli. (2015) Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery. Bioconjugate Chemistry 26:8, pages 1533-1541.
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Concetta Avitabile, Amelia Cimmino & Alessandra Romanelli. (2014) Oligonucleotide Analogues as Modulators of the Expression and Function of Noncoding RNAs (ncRNAs): Emerging Therapeutics Applications. Journal of Medicinal Chemistry 57:24, pages 10220-10240.
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Mallikarjunachari V. N. Uppuladinne, Vinod Jani, Uddhavesh B. Sonavane & Rajendra R. Joshi. (2013) Quantum chemical studies of novel 2′-4′ conformationally restricted antisense monomers. International Journal of Quantum Chemistry 113:23, pages 2523-2533.
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Arpita De, Serhiy Souchelnytskyi, Albert van den Berg & Edwin T. Carlen. (2013) Peptide Nucleic Acid (PNA)–DNA Duplexes: Comparison of Hybridization Affinity between Vertically and Horizontally Tethered PNA Probes. ACS Applied Materials & Interfaces 5:11, pages 4607-4612.
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Pedro Merino & Rosa Matute. 2013. Chemical Synthesis of Nucleoside Analogues. Chemical Synthesis of Nucleoside Analogues 847 880 .
Rolf A. Kramer, Konrad H. Bleicher & Helma Wennemers. (2012) Design and Synthesis of Nucleoproline Amino Acids for the Straightforward Preparation of Chiral and Conformationally Constrained Nucleopeptides. Helvetica Chimica Acta 95:12, pages 2621-2634.
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Glen F. Deleavey & Masad J. Damha. (2012) Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing. Chemistry & Biology 19:8, pages 937-954.
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Concetta Avitabile, Loredana Moggio, Gaetano Malgieri, Domenica Capasso, Sonia Di Gaetano, Michele Saviano, Carlo Pedone & Alessandra Romanelli. (2012) γ sulphate PNA (PNA S): Highly Selective DNA Binding Molecule Showing Promising Antigene Activity. PLoS ONE 7:5, pages e35774.
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Jasbir Singh, Harmeet Kaur, Aditi Kaushik & Sapna Peer. (2011) A Review of Antisense Therapeutic Interventions for Molecular Biological Targets in Various Diseases. International Journal of Pharmacology 7:3, pages 294-315.
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Matthew J. Crawford, Srinivas Rapireddy, Raman Bahal, Iulia Sacui & Danith H. Ly. (2011) Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs. Journal of Nucleic Acids 2011, pages 1-10.
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Soccorsa Pensato, Michele Saviano, Nicoletta Bianchi, Monica Borgatti, Enrica Fabbri, Roberto Gambari & Alessandra Romanelli. (2010) γ-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions. Bioorganic Chemistry 38:5, pages 196-201.
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Joanne I. Yeh, Boris Shivachev, Srinivas Rapireddy, Matthew J. Crawford, Roberto R. Gil, Shoucheng Du, Marcela Madrid & Danith H. Ly. (2010) Crystal Structure of Chiral γPNA with Complementary DNA Strand: Insights into the Stability and Specificity of Recognition and Conformational Preorganization. Journal of the American Chemical Society 132:31, pages 10717-10727.
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Alain J. Cozzone. (2009) Bacterial tyrosine kinases: novel targets for antibacterial therapy?. Trends in Microbiology 17:12, pages 536-543.
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Neil M. Bell & Jason Micklefield. (2009) Chemical Modification of Oligonucleotides for Therapeutic, Bioanalytical and other Applications. ChemBioChem 10:17, pages 2691-2703.
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Norbert Sewald & Hans‐Dieter Jakubke. 2009. Peptides: Chemistry and Biology. Peptides: Chemistry and Biology 411 455 .
Yousef Ahmadibeni & Keykavous Parang. (2008) Solid‐Supported Diphosphitylating and Triphosphitylating Reagents for Nucleoside Modification. Current Protocols in Nucleic Acid Chemistry 33:1.
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