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Expert Opinion on Biological Therapy Volume 8, 2008 - Issue 8
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New therapeutic applications for the anticoagulant, activated protein C

Chris Jackson University of Sydney at Royal North Shore Hospital, Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, Level 1, Block 4, St Leonards NSW, 2065 Australia +61 2 99266043; +61 2 99266269; [email protected]
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Kaley Whitmont University of Sydney at Royal North Shore Hospital, Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, Level 1, Block 4, St Leonards NSW, 2065 Australia +61 2 99266043; +61 2 99266269; [email protected]
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Sara Tritton University of Sydney at Royal North Shore Hospital, Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, Level 1, Block 4, St Leonards NSW, 2065 Australia +61 2 99266043; +61 2 99266269; [email protected]
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Lyn March University of Sydney at Royal North Shore Hospital, Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, Level 1, Block 4, St Leonards NSW, 2065 Australia +61 2 99266043; +61 2 99266269; [email protected]
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Philip Sambrook University of Sydney at Royal North Shore Hospital, Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, Level 1, Block 4, St Leonards NSW, 2065 Australia +61 2 99266043; +61 2 99266269; [email protected]
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Meilang Xue University of Sydney at Royal North Shore Hospital, Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, Level 1, Block 4, St Leonards NSW, 2065 Australia +61 2 99266043; +61 2 99266269; [email protected]
Pages 1109-1122 | Published online: 09 Jul 2008

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Duygu Çimen, Nilay Bereli & Adil Denizli. (2020) Metal-chelated magnetic nanoparticles for protein C purification. Separation Science and Technology 55:13, pages 2259-2268.
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Articles from other publishers (20)

Hakan Orbay, Alain C. Corcos, Jenny A. Ziembicki & Francesco M. Egro. (2023) Challenges in the Management of Large Burns. Clinics in Plastic Surgery.
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Mukesh Kumar Sriwastva, Remesh Kunjunni, Mutahar Andrabi, Kameshwar Prasad, Renu Saxena & Vivekanandhan Subbiah. (2020) Neuroprotective Effects of Activated Protein C Involve the PARP/AIF Pathway against Oxygen-Glucose Deprivation in SH-SY5Y Cells. Brain Sciences 10:12, pages 959.
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Evelyn J. Salvaris, Christopher J. Moran, Jean Christian Roussel, Nella Fisicaro, Simon C. Robson & Peter J. Cowan. (2020) Pig endothelial protein C receptor is functionally compatible with the human protein C pathway. Xenotransplantation 27:2.
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Thomas Charles LangRuilong ZhaoAlbert KimAruna WijewardenaJohn VandervordMeilang XueChristopher John Jackson. (2019) A Critical Update of the Assessment and Acute Management of Patients with Severe Burns. Advances in Wound Care 8:12, pages 607-633.
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Thomas Charles Lang, Ruilong Zhao, Albert Kim, Aruna Wijewardena, John Vandervord, Rachel McGrath, Siobhan Fitzpatrick, Gregory Fulcher & Christopher John Jackson. (2019) Plasma protein C levels are directly associated with better outcomes in patients with severe burns. Burns 45:7, pages 1659-1672.
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Binnaz Demirci, Nilay Bereli, Sevgi Aslıyüce, Gözde Baydemir & Adil Denizli. (2017) Protein C recognition by ion-coordinated imprinted monolithic cryogels. Journal of Separation Science 40:7, pages 1610-1620.
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James Melrose. (2016) Glycosaminoglycans in Wound Healing. Bone and Tissue Regeneration Insights 7, pages BTRI.S38670.
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AS Bischofberger, AS Tsang, N Horadagoda, CM Dart, NR Perkins, LB Jeffcott, CJ Jackson & AJ Dart. (2015) Effect of activated protein C in second intention healing of equine distal limb wounds: a preliminary study. Australian Veterinary Journal 93:10, pages 361-366.
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Meilang Xue & Christopher John Jackson. (2015) Novel Functions of the Anticoagulant Activated Protein C in Maintaining Skin Barrier Integrity to Impact on Skin Disease. Pathobiology 82:2, pages 100-106.
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Kaitlin Shen, Ciara M. Murphy, Ben Chan, Mille Kolind, Tegan L. Cheng, Kathy Mikulec, Lauren Peacock, Meilang Xue, Sang-Youel Park, David G. Little, Chris J. Jackson & Aaron Schindeler. (2014) Activated protein C (APC) can increase bone anabolism via a protease-activated receptor (PAR)1/2 dependent mechanism. Journal of Orthopaedic Research 32:12, pages 1549-1556.
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S. Kapila, I. Reid, S. Dixit, G. Fulcher, L. March, C. Jackson & A. Cooper. (2014) Use of dermal injection of activated protein C for treatment of large chronic wounds secondary to pyoderma gangrenosum. Clinical and Experimental Dermatology 39:7, pages 785-790.
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K. Whitmont, G. Fulcher, I. Reid, M. Xue, K. McKelvey, Y. Xie, M. Aboud, C. Ward, M. M. Smith, A. Cooper, L. March & C. J. Jackson. (2013) Low Circulating Protein C Levels Are Associated with Lower Leg Ulcers in Patients with Diabetes. BioMed Research International 2013, pages 1-4.
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K.F.E. Lee, B. Lu, J.C. Roussel, L.J. Murray-Segal, E.J. Salvaris, S.J. Hodgkinson, B.M. Hall, A.J.F. d’Apice, P.J. Cowan & H. Gock. (2012) Protective Effects of Transgenic Human Endothelial Protein C Receptor Expression in Murine Models of Transplantation. American Journal of Transplantation 12:9, pages 2363-2372.
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Roger Lundblad. 2012. Biotechnology of Plasma Proteins. Biotechnology of Plasma Proteins 367 400 .
Meilang Xue, Suat Dervish, Leonard C. Harrison, Gregory Fulcher & Christopher J. Jackson. (2012) Activated Protein C Inhibits Pancreatic Islet Inflammation, Stimulates T Regulatory Cells, and Prevents Diabetes in Non-obese Diabetic (NOD) Mice. Journal of Biological Chemistry 287:20, pages 16356-16364.
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John H. Griffin, Berislav V. Zlokovic & Laurent O. Mosnier. (2012) Protein C anticoagulant and cytoprotective pathways. International Journal of Hematology 95:4, pages 333-345.
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Julia Lichtnekert, Khader Valli Rupanagudi, Onkar P. Kulkarni, Murthy Narayana Darisipudi, Ramanjaneyulu Allam & Hans-Joachim Anders. (2011) Activated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice. The Journal of Immunology 187:6, pages 3413-3421.
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Aruna Wijewardena, Elle Vandervord, Sepehr Seyed Lajevardi, John Vandervord & Christopher John Jackson. (2011) Combination of Activated Protein C and Topical Negative Pressure Rapidly Regenerates Granulation Tissue Over Exposed Bone to Heal Recalcitrant Orthopedic Wounds. The International Journal of Lower Extremity Wounds 10:3, pages 146-151.
Crossref
Nikita Minhas, Meilang Xue, Kenji Fukudome & Christopher J. Jackson. (2009) Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function. The FASEB Journal 24:3, pages 873-881.
Crossref
L. Gorbacheva, V. Pinelis, S. Ishiwata, S. Strukova & G. Reiser. (2010) Activated protein C prevents glutamate- and thrombin-induced activation of nuclear factor-κB in cultured hippocampal neurons. Neuroscience 165:4, pages 1138-1146.
Crossref

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