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Review

Update on emerging drugs for sarcopenia – age-related muscle wasting

Pages 655-673 | Published online: 02 Dec 2008

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Justin P. Hardee & Gordon S. Lynch. (2019) Current pharmacotherapies for sarcopenia. Expert Opinion on Pharmacotherapy 20:13, pages 1645-1657.
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Stefan M Gehrig & Gordon S Lynch. (2011) Emerging drugs for treating skeletal muscle injury and promoting muscle repair. Expert Opinion on Emerging Drugs 16:1, pages 163-182.
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Kate T Murphy & Gordon S Lynch. (2009) Update on emerging drugs for cancer cachexia. Expert Opinion on Emerging Drugs 14:4, pages 619-632.
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Articles from other publishers (23)

Dorota Skrzypczak, Alicja Ewa Ratajczak, Aleksandra Szymczak-Tomczak, Agnieszka Dobrowolska, Piotr Eder & Iwona Krela-Kaźmierczak. (2021) A Vicious Cycle of Osteosarcopenia in Inflammatory Bowel Diseases—Aetiology, Clinical Implications and Therapeutic Perspectives. Nutrients 13:2, pages 293.
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Dijoia B. Darden, Frederick A. Moore, Scott C. Brakenridge, Eduardo B. Navarro, Stephen D. Anton, Christiaan Leeuwenburgh, Lyle L. Moldawer, Alicia M. Mohr, Philip A. Efron & Robert T. Mankowski. (2021) The Effect of Aging Physiology on Critical Care. Critical Care Clinics 37:1, pages 135-150.
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Humberto D.J. Gonzalez Marrero, Erik V. Stålberg, Gerald Cooray, Rebeca Corpeno Kalamgi, Yvette Hedström, Bo-Michael Bellander, Inger Nennesmo & Lars Larsson. (2020) Neurogenic vs. Myogenic Origin of Acquired Muscle Paralysis in Intensive Care Unit (ICU) Patients: Evaluation of Different Diagnostic Methods. Diagnostics 10:11, pages 966.
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Gordon S. Lynch. 2019. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Marin Jane McBrideKevin P. Foley, Donna M. D’Souza, Yujin E. LiTrevor C. Lau, Thomas J. Hawke & Jonathan D. Schertzer. (2017) The NLRP3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice. American Journal of Physiology-Endocrinology and Metabolism 313:2, pages E222-E232.
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Gloria Gabriela Peña Ordóñez, Lilia Patricia Bustamante Montes, Ninfa Ramírez Duran, Carmen Sánchez Castellano & Alfonso J. Cruz-Jentoft. (2016) Populations and outcome measures used in ongoing research in sarcopenia. Aging Clinical and Experimental Research 29:4, pages 695-700.
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A. Oliveira & C. Vaz. (2015) The role of sarcopenia in the risk of osteoporotic hip fracture. Clinical Rheumatology 34:10, pages 1673-1680.
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Maren S. Fragala, Anne M. Kenny & George A. Kuchel. (2015) Muscle Quality in Aging: a Multi-Dimensional Approach to Muscle Functioning with Applications for Treatment. Sports Medicine 45:5, pages 641-658.
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Frédéric De Ceuninck, Armel Fradin & Philippe Pastoureau. (2014) Bearing arms against osteoarthritis and sarcopenia: when cartilage and skeletal muscle find common interest in talking together. Drug Discovery Today 19:3, pages 305-311.
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C.-S. Chiu, N. Peekhaus, H. Weber, S. Adamski, E. M. Murray, H. Z. Zhang, J. Z. Zhao, R. Ernst, J. Lineberger, L. Huang, R. Hampton, B. A. Arnold, S. Vitelli, L. Hamuro, W.-R. Wang, N. Wei, G. M. Dillon, J. Miao, S. E. Alves, H. Glantschnig, F. Wang & H. A. Wilkinson. (2013) Increased Muscle Force Production and Bone Mineral Density in ActRIIB-Fc-Treated Mature Rodents. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 68:10, pages 1181-1192.
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Heinrich Burkhardt. 2013. Drug Therapy for the Elderly. Drug Therapy for the Elderly 303 309 .
Kate T. MurphyDaniel J. HamJarrod E. ChurchTimur NaimJennifer TrieuDavid A. WilliamsGordon S. Lynch. (2012) Parvalbumin Gene Transfer Impairs Skeletal Muscle Contractility in Old Mice. Human Gene Therapy 23:8, pages 824-836.
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H. P. Patel, K. A. Jameson, H. E. Syddall, H. J. Martin, C. E. Stewart, C. Cooper & A. A. Sayer. (2011) Developmental Influences, Muscle Morphology, and Sarcopenia in Community-Dwelling Older Men. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 67A:1, pages 82-87.
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Abraham Adunsky, Julie Chandler, Norman Heyden, Jeannine Lutkiewicz, Boyd B. Scott, Yuliya Berd, Nancy Liu & Dimitris A. Papanicolaou. (2011) MK-0677 (ibutamoren mesylate) for the treatment of patients recovering from hip fracture: A multicenter, randomized, placebo-controlled phase IIb study. Archives of Gerontology and Geriatrics 53:2, pages 183-189.
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Daniel?C. Andersson, Matthew?J. Betzenhauser, Steven Reiken, Albano?C. Meli, Alisa Umanskaya, Wenjun Xie, Takayuki Shiomi, Ran Zalk, Alain Lacampagne & Andrew?R. Marks. (2011) Ryanodine Receptor Oxidation Causes Intracellular Calcium Leak and Muscle Weakness in Aging. Cell Metabolism 14:2, pages 196-207.
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Lisa Staunton, Kathleen O'Connell & Kay Ohlendieck. (2011) Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging. Journal of Aging Research 2011, pages 1-9.
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Gordon S. Lynch. 2011. Sarcopenia – Age-Related Muscle Wasting and Weakness. Sarcopenia – Age-Related Muscle Wasting and Weakness 1 7 .
Harnish P Patel, Holly E Syddall, Helen J Martin, Claire E Stewart, Cyrus Cooper & Avan Aihie Sayer. (2010) Hertfordshire sarcopenia study: design and methods. BMC Geriatrics 10:1.
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Kate T. Murphy, René Koopman, Timur Naim, Bertrand Léger, Jennifer Trieu, Chikwendu Ibebunjo & Gordon S. Lynch. (2010) Antibody‐directed myostatin inhibition in 21‐mo‐old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function. The FASEB Journal 24:11, pages 4433-4442.
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Steven G. Coca. (2010) Acute Kidney Injury in Elderly Persons. American Journal of Kidney Diseases 56:1, pages 122-131.
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Ferran Masan?s Tor?n, Marga Navarro L?pez, Emilio Sacanella Meseguer & Alfonso L?pez Soto. (2010) ?Qu? es la sarcopenia?. Seminarios de la Fundaci?n Espa?ola de Reumatolog?a 11:1, pages 14-23.
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. (2009) Current World Literature. Current Opinion in Supportive & Palliative Care 3:4, pages 305-312.
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. (2009) Current World Literature. Current Opinion in Neurology 22:5, pages 554-561.
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