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Expert Opinion on Emerging Drugs Volume 11, 2006 - Issue 1
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Editorial

New chelation therapies and emerging chelating drugs for the treatment of iron overload

George J Kontoghiorghes Visiting Professor and Director, Postgraduate Research Institute of Science, Technology, Environment and Medicine, 3 Ammochostou Street, Limassol 3021, Cyprus. [email protected]
Pages 1-5 | Published online: 27 Feb 2006

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Vip Viprakasit, Sarayuth Rodmai & Somdet Srichairatanakool. (2014) Deferiprone for transfusional iron overload and its roles in developing countries. Expert Opinion on Orphan Drugs 2:2, pages 189-200.
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Maria Tsironi, George Assimakopoulos, Katerina Polonofi, Kalliopi Rigaki & Athanassios Aessopos. (2008) Effects of Combined Deferiprone and Deferoxamine Chelation Therapy on Iron Load Indices in β-Thalassemia. Hemoglobin 32:1-2, pages 29-34.
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E. D. Weinberg. (2007) Iron loading in humans: A risk factor for enhanced morbidity and mortality. Journal of Nutritional & Environmental Medicine 16:1, pages 43-51.
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Articles from other publishers (13)

George J. Kontoghiorghes. (2023) Deferiprone and Iron–Maltol: Forty Years since Their Discovery and Insights into Their Drug Design, Development, Clinical Use and Future Prospects. International Journal of Molecular Sciences 24:5, pages 4970.
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Behnoush Khasheii, Pezhman Mahmoodi & Abdolmajid Mohammadzadeh. (2021) Siderophores: Importance in bacterial pathogenesis and applications in medicine and industry. Microbiological Research 250, pages 126790.
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Kavita Gaur, Alexandra Vázquez-Salgado, Geraldo Duran-Camacho, Irivette Dominguez-Martinez, Josué Benjamín-Rivera, Lauren Fernández-Vega, Lesly Carmona Sarabia, Angelys Cruz García, Felipe Pérez-Deliz, José Méndez Román, Melissa Vega-Cartagena, Sergio Loza-Rosas, Xaymara Rodriguez Acevedo & Arthur Tinoco. (2018) Iron and Copper Intracellular Chelation as an Anticancer Drug Strategy. Inorganics 6:4, pages 126.
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Vincent Corcé, Sébastien G. Gouin, Stéphanie Renaud, François Gaboriau & David Deniaud. (2016) Recent advances in cancer treatment by iron chelators. Bioorganic & Medicinal Chemistry Letters 26:2, pages 251-256.
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Oriana Marques, Berta Martins da Silva, Graça Porto & Carlos Lopes. (2014) Iron homeostasis in breast cancer. Cancer Letters 347:1, pages 1-14.
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D.R. Richardson, D.S. Kalinowski, S. Lau, P.J. Jansson & D.B. Lovejoy. (2009) Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents. Biochimica et Biophysica Acta (BBA) - General Subjects 1790:7, pages 702-717.
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Přemysl Mladěnka, Vladimír Semecký, Zuzana Bobrovová, Petr Nachtigal, Jaroslava Vávrová, Magdaléna Holečková, Vladimir Palicka, Yvona Mazurová & Radomír Hrdina. (2008) The effects of lactoferrin in a rat model of catecholamine cardiotoxicity. BioMetals 22:2, pages 353-361.
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Trevor M. Penning & Caryn Lerman. (2008) Genomics of Smoking Exposure and Cessation: Lessons for Cancer Prevention and Treatment. Cancer Prevention Research 1:2, pages 80-83.
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Christiane Vermylen. (2007) What is new in iron overload?. European Journal of Pediatrics 167:4, pages 377-381.
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P. Valent, O. Krieger, R. Stauder, F. Wimazal, T. Nösslinger, W. R. Sperr, H. Sill, P. Bettelheim & M. Pfeilstöcker. (2008) Iron overload in myelodysplastic syndromes (MDS) – diagnosis, management, and response criteria: a proposal of the Austrian MDS platform. European Journal of Clinical Investigation 38:3, pages 143-149.
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Concettina La Motta, Stefania Sartini, Laura Mugnaini, Francesca Simorini, Sabrina Taliani, Silvia Salerno, Anna Maria Marini, Federico Da Settimo, Antonio Lavecchia, Ettore Novellino, Miriam Cantore, Paola Failli & Mario Ciuffi. (2007) Pyrido[1,2- a ]pyrimidin-4-one Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors Exhibiting Antioxidant Activity . Journal of Medicinal Chemistry 50:20, pages 4917-4927.
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John H. Van Drie. (2007) Computer-aided drug design: the next 20 years. Journal of Computer-Aided Molecular Design 21:10-11, pages 591-601.
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Claudia R Morris, Sylvia T Singer & Mark C Walters. (2007) Clinical hemoglobinopathies: iron, lungs and new blood. Current Opinion in Internal Medicine 6:1, pages 60-71.
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