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Expert Opinion on Emerging Drugs Volume 12, 2007 - Issue 2
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Review

Emerging disease-modifying therapies for the treatment of motor neuron disease/amyotropic lateral sclerosis

Richard S Bedlack MD PhD Duke University Medical Center, Box 3333, Durham NC 27705, USA + 1 919 668 2839; + 1 919 668 2901; [email protected]
,
Bryan J Traynor MD National Institute of Mental Health, Bethesda MD, USA
&
Merit E Cudkowicz MD Harvard Medical School, Massachusetts General Hospital, Boston MA, USA
Pages 229-252 | Published online: 29 Jun 2007

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Andrea Barp, Francesca Gerardi, Andrea Lizio, Valeria Ada Sansone & Christian Lunetta. (2020) Emerging Drugs for the Treatment of Amyotrophic Lateral Sclerosis: A Focus on Recent Phase 2 Trials. Expert Opinion on Emerging Drugs 25:2, pages 145-164.
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Svitlana Garbuzova-Davis, Avery Thomson, Crupa Kurien, R. Douglas Shytle & Paul R. Sanberg. (2016) Potential new complication in drug therapy development for amyotrophic lateral sclerosis. Expert Review of Neurotherapeutics 16:12, pages 1397-1405.
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Daniel J. Amante, Jinho Kim, Samantha T. Carreiro, Andrew C. Cooper, Steven W. Jones, Ting Li, Jennifer P. Moody, Christina K. Edgerly, Olivia L. Bordiuk, Kerry Cormier, Karen Smith, Robert J. Ferrante & James Rusche. (2010) Uridine ameliorates the pathological phenotype in transgenic G93A-ALS mice. Amyotrophic Lateral Sclerosis 11:6, pages 520-530.
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Stefano Zoccolella, Caterina Bendotti, Ettore Beghi & Giancarlo Logroscino. (2010) Homocysteine levels and amyotrophic lateral sclerosis: A possible link. Amyotrophic Lateral Sclerosis 11:1-2, pages 140-147.
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Stefano Zoccolella, Andrea Santamato & Paolo Lamberti. (2009) Current and emerging treatments for amyotrophic lateral sclerosis. Neuropsychiatric Disease and Treatment 5, pages 577-595.
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Richard S. Bedlack, Daniel Pastula, Emily Welsh, Darlene Pulley & Merit E. Cudkowicz. (2008) Scrutinizing enrollment in ALS clinical trials: Room for improvement?. Amyotrophic Lateral Sclerosis 9:5, pages 257-265.
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Long He, Shuting Wen, Zhuotai Zhong, Senhui Weng, Qilong Jiang, Hong Mi & Fengbin Liu. (2021) The Synergistic Effects of 5-Aminosalicylic Acid and Vorinostat in the Treatment of Ulcerative Colitis. Frontiers in Pharmacology 12.
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Teresa Cunha-Oliveira, Liliana Montezinho, Catarina Mendes, Omidreza Firuzi, Luciano Saso, Paulo J. Oliveira & Filomena S. G. Silva. (2020) Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention. Oxidative Medicine and Cellular Longevity 2020, pages 1-29.
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Zamanzima Mazibuko, Yahya E. Choonara, Pradeep Kumar, Lisa C. Du Toit, Girish Modi, Dinesh Naidoo & Viness Pillay. (2015) A Review of the Potential Role of Nano-Enabled Drug Delivery Technologies in Amyotrophic Lateral Sclerosis: Lessons Learned from Other Neurodegenerative Disorders. Journal of Pharmaceutical Sciences 104:4, pages 1213-1229.
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Vedrana Tadic, Tino Prell, Janin Lautenschlaeger & Julian Grosskreutz. (2014) The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis. Frontiers in Cellular Neuroscience 8.
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Mohammad Ali Esmaeili & Mahmoud Kiaei. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants 3167 3194 .
Petra Kaufmann. (2012) Clinical research for neuropathies. Journal of the Peripheral Nervous System 17, pages 40-42.
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Mark Lindner & Robert McArthur. 2012. The Mouse Nervous System. The Mouse Nervous System 738 751 .
Daniel B. Drachman, Robert N. Adams, Uma Balasubramanian & Yang Lu. (2010) Strategy for Treating Motor Neuron Diseases Using a Fusion Protein of Botulinum Toxin Binding Domain and Streptavidin for Viral Vector Access: Work in Progress. Toxins 2:12, pages 2872-2889.
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Gregor P. Lotz & Paul J. Muchowski. 2010. Protein Misfolding Diseases. Protein Misfolding Diseases 945 966 .
David L. Clark, Nash N. Boutros & Mario F. Mendez. 2010. The Brain and Behavior. The Brain and Behavior 14 32 .
Richard S. Bedlack & Swati Aggarwal. (2009) ALS UPDATE. CONTINUUM: Lifelong Learning in Neurology 15, pages 83-110.
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Jinsy Andrews. (2008) Amyotrophic lateral sclerosis: Clinical management and research update. Current Neurology and Neuroscience Reports 9:1, pages 59-68.
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Benjamin Rix Brooks. (2009) Managing amyotrophic lateral sclerosis: Slowing disease progression and improving patient quality of life. Annals of Neurology 65:S1, pages S17-S23.
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