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Expert Opinion on Emerging Drugs Volume 12, 2007 - Issue 3
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Review

Emerging drugs for epilepsy

Patrick Kwan The Chinese University of Hong Kong, Division of Neurology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Hong Kong, China +852 2632 2211; +852 2646 6563; [email protected]
&
Martin J Brodie The Chinese University of Hong Kong, Division of Neurology, Department of Medicine and Therapeutics, Prince of Wales Hospital, Hong Kong, China +852 2632 2211; +852 2646 6563; [email protected]
Pages 407-422 | Published online: 17 Sep 2007

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Hongju Liu & Xiaoli Xu. (2018) Influence of adjunctive lacosamide in patients with seizures: a systematic review and meta-analysis. International Journal of Neuroscience 128:7, pages 670-676.
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Steve Chung. (2014) USL255 extended-release topiramate for the treatment of epilepsy. Expert Review of Neurotherapeutics 14:10, pages 1127-1137.
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Gaetano Zaccara, Fabio Giovannelli, Massimo Cincotta & Alfonso Iudice. (2013) AMPA receptor inhibitors for the treatment of epilepsy: the role of perampanel. Expert Review of Neurotherapeutics 13:6, pages 647-655.
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Armel Stockis, Sarah Lu, Françoise Tonner & Christian Otoul. (2009) Clinical pharmacology of levetiracetam for the treatment of epilepsy. Expert Review of Clinical Pharmacology 2:4, pages 339-350.
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Stephen Temitayo Bello, Shenghui Xu, Xiao Li, Junming Ren, Peter Jendrichovsky, Feixu Jiang, Zhoujian Xiao, Xiaoxiao Wan, Xi Chen & Jufang He. (2023) Visually or auditorily induced seizures involve the activation of nonhippocampal brain areas and hippocampal removal does not alleviate seizures in a mouse model of temporal lobe epilepsy . Epilepsia.
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Jie Wu, Mayijie Cao, Ying Peng, Baohua Dong, Yunxiu Jiang, Changjiang Hu, Pengjin Zhu, Weidei Xing, Lingying Yu, Runchun Xu & Zhimin Chen. (2023) Research progress on the treatment of epilepsy with traditional Chinese medicine. Phytomedicine 120, pages 155022.
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Manli Jian, Yisen Liu & Xiaoyu Shen. (2023) Updated Insights into Epilepsy Mechanism and Treatment. Highlights in Science, Engineering and Technology 36, pages 1446-1452.
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Himika Wasan, Devendra Singh & Reeta KH. (2021) Safinamide in neurological disorders and beyond: Evidence from preclinical and clinical studies. Brain Research Bulletin 168, pages 165-177.
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Tanitnun Paprad, Montida Veeravigrom & Tayard Desudchit. (2021) Effect of Mozart K.448 on interictal epileptiform discharges in children with epilepsy: A randomized controlled pilot study. Epilepsy & Behavior 114, pages 107177.
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Guoquan Zhou, Ke Chen, Zehui Yang, Danfeng Shao & Huajun Fan. (2020) Solubility and Thermodynamic Model Correlation of Zonisamide in Different Pure Solvents from T   =  (273.15 to 313.15) K . Journal of Chemical & Engineering Data 65:7, pages 3637-3644.
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Linda J. Stephen & Martin J. Brodie. (2020) Pharmacological Management of the Genetic Generalised Epilepsies in Adolescents and Adults. CNS Drugs 34:2, pages 147-161.
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Madeline C. Pelz, Kathleen D. Schoolcraft, Chloe Larson, Mitchell G. Spring & Hassan H. L?pez. (2017) Assessing the role of serotonergic receptors in cannabidiol's anticonvulsant efficacy. Epilepsy & Behavior 73, pages 111-118.
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Harjeet Kaur, Baldeep Kumar & Bikash Medhi. (2016) Antiepileptic drugs in development pipeline: A recent update. eNeurologicalSci 4, pages 42-51.
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Ivana Tyrlikova & Pavel Klein. 2015. Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease. Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease 433 439 .
R. Edward Hogan, Ilan Blatt, Balduin Lawson, Venkatesh Nagaraddi, Toufic A. Fakhoury, Bob Anders, Annie M. Clark, Dawn Laine, Mark B. Halvorsen & Steve S. Chung. (2014) Efficacy of once-daily extended-release topiramate (USL255): A subgroup analysis based on the level of treatment resistance. Epilepsy & Behavior 41, pages 136-139.
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Sabrina Giacoppo, Giuseppe Mandolino, Maria Galuppo, Placido Bramanti & Emanuela Mazzon. (2014) Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases. Molecules 19:11, pages 18781-18816.
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Naoki Amada, Yuki Yamasaki, Claire M. Williams & Benjamin J. Whalley. (2013) Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression. PeerJ 1, pages e214.
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Michael Podell. (2013) Antiepileptic Drug Therapy and Monitoring. Topics in Companion Animal Medicine 28:2, pages 59-66.
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AJ Hill, MS Mercier, TDM Hill, SE Glyn, NA Jones, Y Yamasaki, T Futamura, M Duncan, CG Stott, GJ Stephens, CM Williams & BJ Whalley. (2012) Cannabidivarin is anticonvulsant in mouse and rat. British Journal of Pharmacology 167:8, pages 1629-1642.
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Saulo Fábio Ramos, Bruna Pescador Mendonça, Daniela Dimer Leffa, Robson Pacheco, Adriani Paganini Damiani, Giana Hainzenreder, Fabrícia Petronilho, Felipe Dal-Pizzol, Remo Guerrini, Girolamo Calo'Elaine Cristina Gavioli, Carina Rodrigues Boeck & Vanessa Moraes de Andrade. (2012) Effects of neuropeptide S on seizures and oxidative damage induced by pentylenetetrazole in mice. Pharmacology Biochemistry and Behavior 103:2, pages 197-203.
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Ranjani ManjunathPierre Emmanuel ParadisHélène PariséMarie-Hélène LafeuilleBrian BowersMei Sheng DuhPatrick LefebvreEdward Faught. (2012) Burden of uncontrolled epilepsy in patients requiring an emergency room visit or hospitalization. Neurology 79:18, pages 1908-1916.
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Shivani PonnalaJaydip Ray ChaudhariMomin Abdul JaleelDilnawaz BhiladvalaPrabhakar Rao KaipaUndurti N. DasQurratulain Hasan. (2012) Role of MDR1 C3435T and GABRG2 C588T Gene Polymorphisms in Seizure Occurrence and MDR1 Effect on Anti-Epileptic Drug (Phenytoin) Absorption . Genetic Testing and Molecular Biomarkers 16:6, pages 550-557.
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Philip N. Patsalos. 2012. Introduction to Epilepsy. Introduction to Epilepsy 396 400 .
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Benjamin Legros, Paul Boon, Berten Ceulemans, Thomas Coppens, Karine Geens, Henri Hauman, Lieven Lagae, Alfred Meurs, Leon Mol, Michel Ossemann, Kenou van Rijckevorsel, Michel Van Zandijcke, Pascal Vrielynck, Daniëlla Wagemans & Thierry Grisar. (2012) Development of an electronic decision tool to support appropriate treatment choice in adult patients with epilepsy – Epi-Scope®. Seizure 21:1, pages 32-39.
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Heidrun Potschka & Martin J. Brodie. 2012. Epilepsy. Epilepsy 741 757 .
Charles D. Ciccone. 2012. Geriatric Physical Therapy. Geriatric Physical Therapy 38 63 .
Irene García-Morales, Rafael Toledano Delgado, Mercé Falip, Dulce Campos, María Eugenia García & Antonio Gil-Nagel. (2011) Early clinical experience with lacosamide as adjunctive therapy in patients with refractory focal epilepsy and nocturnal seizures. Seizure 20:10, pages 801-804.
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Chunbo Zhang, Zhong Zuo, Patrick Kwan & Larry Baum. (2011) In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein. Epilepsia 52:10, pages 1894-1904.
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Martin J. Brodie & Graeme J. Sills. (2011) Combining antiepileptic drugs?Rational polytherapy?. Seizure 20:5, pages 369-375.
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L. Alves, V. Hülsmeyer, A. Jaggy, A. Fischer, T. Leeb & M. Drögemüller. (2011) Polymorphisms in the ABCB1 Gene in Phenobarbital Responsive and Resistant Idiopathic Epileptic Border Collies . Journal of Veterinary Internal Medicine 25:3, pages 484-489.
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Linda J. Stephen & Martin J. Brodie. (2011) Pharmacotherapy of Epilepsy. CNS Drugs 25:2, pages 89-107.
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Ramon Edmundo D. Bautista & Deepali Jain. (2011) Detecting health disparities among Caucasians and African-Americans with epilepsy. Epilepsy & Behavior 20:1, pages 52-56.
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Pavel Klein, Jaromir Janousek, Arkady Barber & Randi Weissberger. (2010) Ketogenic diet treatment in adults with refractory epilepsy. Epilepsy & Behavior 19:4, pages 575-579.
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Martin J. Brodie. (2010) Antiepileptic drug therapy the story so far. Seizure 19:10, pages 650-655.
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Steve Chung, Michael R. Sperling, Victor Biton, Gregory Krauss, David Hebert, G. David Rudd & Pamela Doty. (2010) Lacosamide as adjunctive therapy for partial‐onset seizures: A randomized controlled trial. Epilepsia 51:6, pages 958-967.
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Giulia Curia, Giuseppe Biagini, Emilio Perucca & Massimo Avoli. (2009) Lacosamide. CNS Drugs 23:7, pages 555-568.
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Ranjani Manjunath, Keith L. Davis, Sean D. Candrilli & Alan B. Ettinger. (2009) Association of antiepileptic drug nonadherence with risk of seizures in adults with epilepsy. Epilepsy & Behavior 14:2, pages 372-378.
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