674
Views
41
CrossRef citations to date
0
Altmetric
Reviews

Addressing current medical needs in invasive fungal infection prevention and treatment with new antifungal agents, strategies and formulations

, PharmD, , PharmD MS BCPS FCCP & , MD
Pages 559-586 | Published online: 17 Aug 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Paul Vandecruys, Silke Baldewijns, Mart Sillen, Wouter Van Genechten & Patrick Van Dijck. (2023) Oteseconazole: a long-awaited diversification of the antifungal arsenal to manage recurrent vulvovaginal candidiasis (RVVC). Expert Review of Anti-infective Therapy 21:8, pages 799-812.
Read now
Ya-Lin Chang, Shang-Jie Yu, Joseph Heitman, Melanie Wellington & Ying-Lien Chen. (2017) New facets of antifungal therapy. Virulence 8:2, pages 222-236.
Read now
Seungeun Lee, Shinah Kang, Chemmeri Padasseri Bivila, Chungsik Yoon, Jeongsun Yang & Naomichi Yamamoto. (2015) Removal of Viable Airborne Fungi from Indoor Environments by Benzalkonium Chloride-Based Aerosol Disinfectants. Human and Ecological Risk Assessment: An International Journal 21:8, pages 2174-2191.
Read now
David Andes. (2013) Optimizing antifungal choice and administration. Current Medical Research and Opinion 29:sup4, pages 13-18.
Read now
John R. Perfect & David Andes. (2013) Antifungal therapy: current concepts and evidence-based management. Current Medical Research and Opinion 29:3, pages 289-290.
Read now
Gérald E Piérard, Trinh Hermanns-Lê, Philippe Delvenne & Claudine Piérard-Franchimont. (2012) Miconazole, a pharmacological barrier to skin fungal infections. Expert Opinion on Pharmacotherapy 13:8, pages 1187-1194.
Read now

Articles from other publishers (35)

Ruofei Zhang, Yuxi Wang, Aijia Wu, Jiaxing Wang & Jifa Zhang. (2023) Strategies of targeting CYP51 for IFIs therapy: Emerging prospects, opportunities and challenges. European Journal of Medicinal Chemistry 259, pages 115658.
Crossref
Megha Kaushik, Arvind Sharma, Shefali Gupta & Pooja Gulati. 2023. Current Trends in the Identification and Development of Antimicrobial Agents. Current Trends in the Identification and Development of Antimicrobial Agents 125 166 .
Ram Kumar Sahu, Mounir M. Salem-Bekhit, Bedanta Bhattacharjee, Yosif Almoshari, Abu Md Ashif Ikbal, Meshal Alshamrani, Alakesh Bharali, Ahmad Salawi, Retno Widyowati, Abdulrahman Alshammari & Ibrahim Elbagory. (2021) Mucormycosis in Indian COVID-19 Patients: Insight into Its Patho-Genesis, Clinical Manifestation, and Management Strategies. Antibiotics 10:9, pages 1079.
Crossref
Shivani Verma & Puneet Utreja. (2021) Oleic Acid Vesicles as a New Approach for Transdermal Delivery of Econazole Nitrate: Development, Characterization, and In-vivo Evaluation in Wistar Rats. Recent Advances in Anti-Infective Drug Discovery 16:1, pages 30-49.
Crossref
Grigoris Zoidis, Eftichia Kritsi, Paulina Lecinska, Marija Ivanov, Panagiotis Zoumpoulakis, Marina Sokovic & Marco Catto. (2020) The Triazole Ring as a Privileged Scaffold for Putative Antifungals: Synthesis and Evaluation of a Series of New Analogues. ChemMedChem 16:1, pages 134-144.
Crossref
Zhen Jie Low, Juan Xiong, Ying Xie, Guang-Lei Ma, Howard Saw, Hoa Thi Tran, Soo Lin Wong, Li Mei Pang, July Fong, Peng Lu, Jin-Feng Hu, Yang Liang, Yansong Miao & Zhao-Xun Liang. (2020) Discovery, biosynthesis and antifungal mechanism of the polyene-polyol meijiemycin. Chemical Communications 56:5, pages 822-825.
Crossref
Young-Guk Na, Hyun Wook Huh, Min-Ki Kim, Jin-Ju Byeon, Min-Gu Han, Hong-Ki Lee & Cheong-Weon Cho. (2020) Development and evaluation of a film-forming system hybridized with econazole-loaded nanostructured lipid carriers for enhanced antifungal activity against dermatophytes. Acta Biomaterialia 101, pages 507-518.
Crossref
Irfan Khan, Sirisha Kanugala, Mohd. Adil Shareef, Thipparapu Ganapathi, Anver Basha Shaik, Kunta Chandra Shekar, Ahmed Kamal & Chityal Ganesh Kumar. (2019) Synthesis of new bis‐pyrazole linked hydrazides and their in vitro evaluation as antimicrobial and anti‐biofilm agents: A mechanistic role on ergosterol biosynthesis inhibition in Candida albicans . Chemical Biology & Drug Design 94:1, pages 1339-1351.
Crossref
Mohd Adil Shareef, K. Sirisha, Irfan Khan, Ibrahim Bin Sayeed, Surender Singh Jadav, Gopathi Ramu, C. Ganesh Kumar, Ahmed Kamal & Bathini Nagendra Babu. (2019) Design, synthesis, and antimicrobial evaluation of 1,4-dihydroindeno[1,2- c ]pyrazole tethered carbohydrazide hybrids: exploring their in silico ADMET, ergosterol inhibition and ROS inducing potential . MedChemComm 10:5, pages 806-813.
Crossref
Giselle C. de Oliveira Santos, Cleydlenne C. Vasconcelos, Alberto J. O. Lopes, Maria do S. de Sousa Cartágenes, Allan K. D. B. Filho, Flávia R. F. do Nascimento, Ricardo M. Ramos, Emygdia R. R. B. Pires, Marcelo S. de Andrade, Flaviane M. G. Rocha & Cristina de Andrade Monteiro. (2018) Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents. Frontiers in Microbiology 9.
Crossref
John R. Perfect. (2017) The antifungal pipeline: a reality check. Nature Reviews Drug Discovery 16:9, pages 603-616.
Crossref
Christopher M. Yates, Edward P. Garvey, Sammy R. Shaver, Robert J. Schotzinger & William J. Hoekstra. (2017) Design and optimization of highly-selective, broad spectrum fungal CYP51 inhibitors. Bioorganic & Medicinal Chemistry Letters 27:15, pages 3243-3248.
Crossref
Elisa Leyva, Lluvia I. López, Ramón F. García de la Cruz & Claudia G. Espinosa-González. (2016) Synthesis and studies of the antifungal activity of 2-anilino-/2,3-dianilino-/2-phenoxy- and 2,3-diphenoxy-1,4-naphthoquinones. Research on Chemical Intermediates 43:3, pages 1813-1827.
Crossref
David S. Perlin. 2017. Candida albicans: Cellular and Molecular Biology. Candida albicans: Cellular and Molecular Biology 471 489 .
Leah E. Cowen. 2017. Handbook of Antimicrobial Resistance. Handbook of Antimicrobial Resistance 345 368 .
Ana P. Sant'Anna da Silva, Luís C. Nascimento da Silva, Caíque S. Martins da Fonseca, Janete M. de Araújo, Maria T. dos Santos Correia, Marilene da Silva Cavalcanti & Vera L. de Menezes Lima. (2016) Antimicrobial Activity and Phytochemical Analysis of Organic Extracts from Cleome spinosa Jaqc.. Frontiers in Microbiology 7.
Crossref
Yuqi Zhao, Yanjie Wang, Lei Zou & Jingfei Huang. (2016) Reconstruction and applications of consensus yeast metabolic network based on RNA sequencing . FEBS Open Bio 6:4, pages 264-275.
Crossref
Verena Pries, Simona Cotesta, Ralph Riedl, Thomas Aust, Sven Schuierer, Jianshi Tao, Ireos Filipuzzi & Dominic Hoepfner. (2016) Advantages and Challenges of Phenotypic Screens: The Identification of Two Novel Antifungal Geranylgeranyltransferase I Inhibitors. SLAS Discovery 21:3, pages 306-315.
Crossref
William J. Hoekstra, Tatiana Y. Hargrove, Zdzislaw Wawrzak, Denise da Gama Jaen Batista, Cristiane F. da Silva, Aline S. G. Nefertiti, Girish Rachakonda, Robert J. Schotzinger, Fernando Villalta, Maria de Nazaré C. Soeiro & Galina I. Lepesheva. (2016) Clinical Candidate VT-1161's Antiparasitic Effect In Vitro , Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi . Antimicrobial Agents and Chemotherapy 60:2, pages 1058-1066.
Crossref
Seungeun Lee, Siyu Xu, Chemmeri Padasseri Bivila, Hyeyoung Lee, Myung Soo Park, Young Woon Lim & Naomichi Yamamoto. (2015) Triazole Susceptibilities in Thermotolerant Fungal Isolates from Outdoor Air in the Seoul Capital Area in South Korea. PLOS ONE 10:9, pages e0138725.
Crossref
Qi (Tony) Zhou, Sharon Shui Yee Leung, Patricia Tang, Thaigarajan Parumasivam, Zhi Hui Loh & Hak-Kim Chan. (2015) Inhaled formulations and pulmonary drug delivery systems for respiratory infections. Advanced Drug Delivery Reviews 85, pages 83-99.
Crossref
R. Semis, M. Nahmias, S. Lev, M. Frenkel & E. Segal. (2015) Evaluation of antifungal combinations of nystatin-intralipid against Aspergillus terreus using checkerboard and disk diffusion methods. Journal de Mycologie Médicale 25:1, pages 63-70.
Crossref
Naomichi Yamamoto, Karen C. Dannemiller, Kyle Bibby & Jordan Peccia. (2014) Identification accuracy and diversity reproducibility associated with internal transcribed spacer-based fungal taxonomic library preparation. Environmental Microbiology 16:9, pages 2764-2776.
Crossref
William J. Hoekstra, Edward P. Garvey, William R. Moore, Stephen W. Rafferty, Christopher M. Yates & Robert J. Schotzinger. (2014) Design and optimization of highly-selective fungal CYP51 inhibitors. Bioorganic & Medicinal Chemistry Letters 24:15, pages 3455-3458.
Crossref
Takahiro Takuma. (2014) 2. Recent Antifungal Drugs and the Usage. Nihon Naika Gakkai Zasshi 103:11, pages 2721-2727.
Crossref
Leah E. Cowen. 2014. Handbook of Antimicrobial Resistance. Handbook of Antimicrobial Resistance 1 21 .
Gordon M. Cragg & David J. Newman. (2013) Natural products: A continuing source of novel drug leads. Biochimica et Biophysica Acta (BBA) - General Subjects 1830:6, pages 3670-3695.
Crossref
Nir Osherov. (2012) The top three areas of basic research on Aspergillus fumigatus in 2011 . Annals of the New York Academy of Sciences 1273:1, pages 74-77.
Crossref
Charlotte A. Berkes, Leo Li-Ying Chan, Alisha Wilkinson & Benjamin Paradis. (2012) Rapid quantification of pathogenic fungi by Cellometer image-based cytometry. Journal of Microbiological Methods 91:3, pages 468-476.
Crossref
Naomichi Yamamoto, Kyle Bibby, Jing Qian, Denina Hospodsky, Hamid Rismani-Yazdi, William W Nazaroff & Jordan Peccia. (2012) Particle-size distributions and seasonal diversity of allergenic and pathogenic fungi in outdoor air. The ISME Journal 6:10, pages 1801-1811.
Crossref
Dianella Savoia. (2012) Plant-derived antimicrobial compounds: alternatives to antibiotics. Future Microbiology 7:8, pages 979-990.
Crossref
Daniela Secci, Bruna Bizzarri, Adriana Bolasco, Simone Carradori, Melissa D'Ascenzio, Daniela Rivanera, Emanuela Mari, Lucia Polletta & Alessandra Zicari. (2012) Synthesis, anti-Candida activity, and cytotoxicity of new (4-(4-iodophenyl)thiazol-2-yl)hydrazine derivatives. European Journal of Medicinal Chemistry 53, pages 246-253.
Crossref
Sanshu Li & Ronald R. Breaker. (2012) Fluoride enhances the activity of fungicides that destabilize cell membranes. Bioorganic & Medicinal Chemistry Letters 22:9, pages 3317-3322.
Crossref
T. Holm, J. Bruchmann, A. Scheynius & Ü. Langel. (2012) Cell-penetrating peptides as antifungals towards Malassezia sympodialis. Letters in Applied Microbiology 54:1, pages 39-44.
Crossref
Robert P. Rennie. 2012. Antibiotic Resistance. Antibiotic Resistance 45 65 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.