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Review

Prospects and problems of gene therapy: an update

Pages 187-198 | Published online: 25 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Rohidas B Arote, Hu-Lin Jiang, You-Kyoung Kim, Myung-Haing Cho, Yun-Jaie Choi & Chong-Su Cho. (2011) Degradable poly(amido amine)s as gene delivery carriers. Expert Opinion on Drug Delivery 8:9, pages 1237-1246.
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Somayeh Hallaj Nezhadi, Peter F.M. Choong, Farzaneh Lotfipour & Crispin R. Dass. (2009) Gelatin-based delivery systems for cancer gene therapy. Journal of Drug Targeting 17:10, pages 731-738.
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D Jere, HL Jiang, R Arote, YK Kim, YJ Choi, MH Cho, T Akaike & CS Cho. (2009) Degradable polyethylenimines as DNA and small interfering RNA carriers. Expert Opinion on Drug Delivery 6:8, pages 827-834.
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Articles from other publishers (21)

Alok Sharma, Hemangi Sane, Nandini Gokulchandran, Amruta Paranjape, Zubiya Shaikh, Arjun KM & Prerna Badhe. 2023. Potential Therapeutic Strategies for Muscular Dystrophy. Potential Therapeutic Strategies for Muscular Dystrophy.
Yi Yu, Yijun Gao, Liming He, Bairong Fang, Wenhui Ge, Pu Yang, Yikun Ju, Xiaoyan Xie & Lanjie Lei. (2023) Biomaterial‐based gene therapy. MedComm 4:3.
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Vanshika Arora, Ashim Aggarwal, Shivani Aggarwal & Randhir Kumar. (2021) Importance of Genetic Engineering and Gene Therapy in the Management of Viral Diseases and Outbreaks. Journal of Evolution of Medical and Dental Sciences 10:6, pages 357-361.
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Reza Mohammadinejad, Ali Dehshahri, Vijay Sagar Madamsetty, Masoumeh Zahmatkeshan, Shima Tavakol, Pooyan Makvandi, Danial Khorsandi, Abbas Pardakhty, Milad Ashrafizadeh, Elham Ghasemipour Afshar & Ali Zarrabi. (2020) In vivo gene delivery mediated by non-viral vectors for cancer therapy. Journal of Controlled Release 325, pages 249-275.
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Qian Li, Xuefang Hao, Huaning Wang, Jintang Guo, Xiang-kui Ren, Shihai Xia, Wencheng Zhang & Yakai Feng. (2019) Multifunctional REDV-G-TAT-G-NLS-Cys peptide sequence conjugated gene carriers to enhance gene transfection efficiency in endothelial cells. Colloids and Surfaces B: Biointerfaces 184, pages 110510.
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Jafar Rezaie, Saeed Ajezi, Çığır Biray Avci, Mohammad Karimipour, Mohammad Hossein Geranmayeh, Alireza Nourazarian, Emel Sokullu, Aysa Rezabakhsh & Reza Rahbarghazi. (2017) Exosomes and their Application in Biomedical Field: Difficulties and Advantages. Molecular Neurobiology 55:4, pages 3372-3393.
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Ashok Kumar Sharma, Lokesh Gupta & Umesh Gupta. 2017. Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids. Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids 13 42 .
Zhaoyong Wu, Shuyu Zhan, Wei Fan, Xueying Ding, Xin Wu, Wei Zhang, Yinghua Fu, Yueyan Huang, Xuan Huang, Rubing Chen, Mingjuan Li, Ningyin Xu, Yongxia Zheng & Baoyue Ding. (2016) Peptide-Mediated Tumor Targeting by a Degradable Nano Gene Delivery Vector Based on Pluronic-Modified Polyethylenimine. Nanoscale Research Letters 11:1.
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Abhijeet P. Pandey & Krutika K. Sawant. (2016) Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery. Materials Science and Engineering: C 68, pages 904-918.
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Alma Bockuviene, Kristina Slavuckyte, Ausvydas Vareikis, Sarunas Zigmantas, Lolita Zaliauskiene & Ricardas Makuska. (2016) Intracellular Delivery and Triggered Release of DNA Using Biodegradable Poly(2-hydroxypropylene imine)s Containing Cystamine Units. Macromolecular Bioscience 16:10, pages 1497-1505.
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Yong Xin, Qian Huang, Jian-Qin Tang, Xiao-Yang Hou, Pei Zhang, Long Zhen Zhang & Guan Jiang. (2016) Nanoscale drug delivery for targeted chemotherapy. Cancer Letters 379:1, pages 24-31.
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Federico Martello, Martin Piest, Johan F.J. Engbersen & Paolo Ferruti. (2012) Effects of branched or linear architecture of bioreducible poly(amido amine)s on their in vitro gene delivery properties. Journal of Controlled Release 164:3, pages 372-379.
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Min Da Shau, Mei Fen Shih, Chi Cheng Lin, I Chuan Chuang, Wei Chih Hung, Wim E. Hennink & Jong Yuh Cherng. (2012) A one-step process in preparation of cationic nanoparticles with poly(lactide-co-glycolide)-containing polyethylenimine gives efficient gene delivery. European Journal of Pharmaceutical Sciences 46:5, pages 522-529.
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Thi Ngoc Tram Do, Wing-Hin Lee, Ching-Yee Loo, Alexander V Zavgorodniy & Ramin Rohanizadeh. (2012) Hydroxyapatite nanoparticles as vectors for gene delivery. Therapeutic Delivery 3:5, pages 623-632.
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YOU-KYOUNG KIM, QUYNH-PHUONG LUU, MOHAMMAD ARIFUL ISLAM, YUN-JAIE CHOI, CHONG-SU CHO, HU-LIN JIANG & MYUNG-HAING CHO. (2012) DEGRADABLE POLYETHYLENIMINE DERIVATIVES AS GENE CARRIERS. Nano LIFE 02:01, pages 1230004.
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Chong-Su Cho. (2012) Design and Development of Degradable Polyethylenimines for Delivery of DNA and Small Interfering RNA: An Updated Review. ISRN Materials Science 2012, pages 1-24.
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Johannes Geiger, Manish K. Aneja & Carsten Rudolph. (2010) Vectors for pulmonary gene therapy. International Journal of Pharmaceutics 390:1, pages 84-88.
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Yu Zheng, Zheng Cai, Xiangrong Song, Bo Yu, Yueqi Bi, Qiuhong Chen, Dong Zhao, Jiapeng Xu & Shixiang Hou. (2009) Receptor mediated gene delivery by folate conjugated N-trimethyl chitosan in vitro. International Journal of Pharmaceutics 382:1-2, pages 262-269.
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Atul Pathak, Pradeep Kumar, Krishna Chuttani, Sanyog Jain, Anil K. Mishra, Suresh P. Vyas & Kailash C. Gupta. (2009) Gene Expression, Biodistribution, and Pharmacoscintigraphic Evaluation of Chondroitin Sulfate−PEI Nanoconstructs Mediated Tumor Gene Therapy. ACS Nano 3:6, pages 1493-1505.
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Jordy Luten, Cornelus F. van Nostrum, Stefaan C. De Smedt & Wim E. Hennink. (2008) Biodegradable polymers as non-viral carriers for plasmid DNA delivery. Journal of Controlled Release 126:2, pages 97-110.
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J. Luten, M.J. van Steenbergen, M.C. Lok, A.M. de Graaff, C.F. van Nostrum, H. Talsma & W.E. Hennink. (2008) Degradable PEG-folate coated poly(DMAEA-co-BA)phosphazene-based polyplexes exhibit receptor-specific gene expression. European Journal of Pharmaceutical Sciences 33:3, pages 241-251.
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