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Editorial

The cyclooxygenase-2 pathway as a target for treatment or prevention of cancer

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Pages 1-7 | Published online: 02 Mar 2005

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Pujan N. Pandya, Sivakumar Prasanth Kumar, Kinjal Bhadresha, Chirag N. Patel, Saumya K. Patel, Rakesh M. Rawal & Archana U. Mankad. (2020) Identification of promising compounds from curry tree with cyclooxygenase inhibitory potential using a combination of machine learning, molecular docking, dynamics simulations and binding free energy calculations. Molecular Simulation 46:11, pages 812-822.
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Axel H Schönthal, Thomas C Chen, Florence M Hofman, Stan G Louie & Nicos A Petasis. (2008) Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs. Expert Opinion on Investigational Drugs 17:2, pages 197-208.
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. (2004) Carbonic anhydrase/COX-2 inhibitors in the treatment of various diseases. Expert Opinion on Therapeutic Patents 14:12, pages 1803-1806.
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Víctor M. Villaseñor, Jhony Navat Enriquez-Vara, Judith E. Urías-Silva, Eugenia del Carmen Lugo-Cervantes, Diego A. Luna-Vital & Luis Mojica. (2022) Mexican grasshopper (Sphenarium purpurascens) as source of high protein flour: Techno-functional characterization, and in silico and in vitro biological potential. Food Research International 162, pages 112048.
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Mehlika D. Altıntop, Belgin Sever, Gülşen Akalın Çiftçi, İpek Ertorun, Özkan Alataş & Ahmet Özdemir. (2022) A new series of thiosemicarbazone‐based anti‐inflammatory agents exerting their action through cyclooxygenase inhibition. Archiv der Pharmazie 355:9, pages 2200136.
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V.M. Berlin Grace, D. David Wilson, R. Anushya & Siddikuzzaman. (2021) Regulation of inflammation and COX-2 gene expression in benzo (a) pyrene induced lung carcinogenesis in mice by all trans retinoic acid (ATRA). Life Sciences 285, pages 119967.
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Monika Berbecka, Alicja Forma, Jacek Baj, Marzena Furtak-Niczyporuk, Ryszard Maciejewski & Robert Sitarz. (2021) A Systematic Review of the Cyclooxygenase-2 (COX-2) Expression in Rectal Cancer Patients Treated with Preoperative Radiotherapy or Radiochemotherapy. Journal of Clinical Medicine 10:19, pages 4443.
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Ka Woong Wong & Siau Hui Mah. 2021. Bioactive Natural Products. Bioactive Natural Products 393 433 .
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B. Ahmetaj-Shala, A. Tesfai, C. Constantinou, R. Leszczynski, M.V. Chan, H. Gashaw, G. Galaris, S. Mazi, T.D. Warner, N.S. Kirkby & J.A. Mitchell. (2017) Pharmacological assessment of ibuprofen arginate on platelet aggregation and colon cancer cell killing. Biochemical and Biophysical Research Communications 484:4, pages 762-766.
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Philipp Krapf, Raphael Richarz, Elizaveta A. Urusova, Bernd Neumaier & Boris D. Zlatopolskiy. (2015) Seyferth–Gilbert Homologation as a Route to 18 F‐Labeled Building Blocks: Preparation of Radiofluor­inated Phenylacetylenes and Their Application in PET Chemistry . European Journal of Organic Chemistry 2016:3, pages 430-433.
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Hai-Kang Hua, Cheng Jin, Li-Jia Yang, Shi-Qin Tao & Xiao-Hong Zhu. (2015) Expression of Cyclooxygenase-2 in Squamous Cell Carcinoma and Keratoacanthoma and its Clinical Significance. Cell Biochemistry and Biophysics 72:2, pages 475-480.
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Claudio Tabolacci, Alessandro Lentini, Bruno Provenzano, Angelo Gismondi, Stefania Rossi & Simone Beninati. (2010) Similar antineoplastic effects of nimesulide, a selective COX-2 inhibitor, and prostaglandin E1 on B16-F10 murine melanoma cells. Melanoma Research 20:4, pages 273-279.
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C. Chargari, E. Deutsch, C. Le P?choux & N. Magn?. (2009) ?tat des lieux des associations chimioradioth?rapeutiques et place potentielle des th?rapies cibl?es dans les cancers bronchiques non ? petites cellules. Cancer/Radioth?rapie 13:2, pages 114-122.
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Carol A. Rouzer & Lawrence J. Marnett. (2009) Cyclooxygenases: structural and functional insights. Journal of Lipid Research 50, pages S29-S34.
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Deepika Dhawan, Antonella Borgatti Jeffreys, Rong Zheng, Jane C. Stewart & Deborah W. Knapp. (2008) Cyclooxygenase-2 dependent and independent antitumor effects induced by celecoxib in urinary bladder cancer cells. Molecular Cancer Therapeutics 7:4, pages 897-904.
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Dana Yona & Nadir Arber. (2006) Coxibs and Cancer Prevention. Journal of Cardiovascular Pharmacology 47:Supplement 1, pages S76-S81.
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Axel H. Schönthal. (2006) Antitumor properties of dimethyl-celecoxib, a derivative of celecoxib that does not inhibit cyclooxygenase-2: implications for glioma therapy. Neurosurgical Focus 20:4, pages E21.
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J.O. Moody, V.A. Robert, J.D. Connolly & P.J. Houghton. (2006) Anti-inflammatory activities of the methanol extracts and an isolated furanoditerpene constituent of Sphenocentrum jollyanum Pierre (Menispermaceae). Journal of Ethnopharmacology 104:1-2, pages 87-91.
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Moammir H. Aziz, Deric L. Wheeler, Bhushan Bhamb & Ajit K. Verma. (2006) Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2. Cancer Research 66:2, pages 713-722.
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Vattoly J. Majo, Jaya Prabhakaran, Norman R. Simpson, Ronald L. Van Heertum, J. John Mann & J.S. Dileep Kumar. (2005) A general method for the synthesis of aryl [11C]methylsulfones: Potential PET probes for imaging cyclooxygenase-2 expression. Bioorganic & Medicinal Chemistry Letters 15:19, pages 4268-4271.
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D J A de Groot, T Timmer, D C J Spierings, T K P Le, S de Jong & E G E de Vries. (2005) Indomethacin-induced activation of the death receptor-mediated apoptosis pathway circumvents acquired doxorubicin resistance in SCLC cells. British Journal of Cancer 92:8, pages 1459-1466.
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J. W. Pollard. (2005) Review of: Overexpression of the colony-stimulating factor (CSF-1) and/or its receptor c-fms in mammary glands of transgenic mice results in hyperplasia and tumor formation. Breast Cancer Online 8:2.
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Guido Eibl, Yasunori Takata, Laszlo G. Boros, Joey Liu, Yuji Okada, Howard A. Reber & Oscar J. Hines. (2005) Growth Stimulation of COX-2–Negative Pancreatic Cancer by a Selective COX-2 Inhibitor. Cancer Research 65:3, pages 982-990.
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Christian Kamp Nielsen, Joan I.A. Campbell, John F. Öhd, Matthias Mörgelin, Kristian Riesbeck, Göran Landberg & Anita Sjölander. (2005) A Novel Localization of the G-Protein-Coupled CysLT1 Receptor in the Nucleus of Colorectal Adenocarcinoma Cells. Cancer Research 65:3, pages 732-742.
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Guido Eibl, Howard A. Reber, Oscar J. Hines & Vay L. W. Go. (2004) COX and PPAR. Pancreas 29:4, pages 247-253.
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Hassan Fahmi. (2004) mPGES-1 as a novel target for arthritis. Current Opinion in Rheumatology 16:5, pages 623-627.
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Ignacio I. Wistuba & Adi F. Gazdar. (2004) Gallbladder cancer: lessons from a rare tumour. Nature Reviews Cancer 4:9, pages 695-706.
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Saranette Cheng, Hassan Afif, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Xinfang Li, Katherine Farrajota, Martin Lavigne & Hassan Fahmi. (2004) Activation of Peroxisome Proliferator-activated Receptor γ Inhibits Interleukin-1β-induced Membrane-associated Prostaglandin E2 Synthase-1 Expression in Human Synovial Fibroblasts by Interfering with Egr-1. Journal of Biological Chemistry 279:21, pages 22057-22065.
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Gary B. Gordon, Gary J. Kelloff & Caroline C. C. Sigman. 2004. Cancer Chemoprevention. Cancer Chemoprevention 87 105 .

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