393
Views
38
CrossRef citations to date
0
Altmetric
Reviews

PDGFRα: a new therapeutic target in the treatment of hepatocellular carcinoma?

&
Pages 443-454 | Published online: 31 Mar 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Ignacio Erquiaga, Cristina Ormazábal, Cristina Hurtado, Paula Aranaz, María J. Calasanz, Marina García-Delgado, Francisco J. Novo & José L. Vizmanos. (2010) Quantification of PDGFRA alternative transcripts improves the screening for X–PDGFRA fusions by reverse transcriptase-polymerase chain reaction. Leukemia & Lymphoma 51:9, pages 1720-1726.
Read now
Piotr Jan Wysocki. (2010) Targeted therapy of hepatocellular cancer. Expert Opinion on Investigational Drugs 19:2, pages 265-274.
Read now

Articles from other publishers (35)

Sheetal Chauhan, Seema Sen, Khushboo Irshad, Seema Kashyap, Neelam Pushker, Rachna Meel & Mehar Chand Sharma. (2023) Receptor tyrosine kinase gene expression profiling of orbital rhabdomyosarcoma unveils MET as a potential biomarker and therapeutic target. Human Cell.
Crossref
Ece Sariyar & Zeynep Firtina Karagonlar. (2023) Modelling the Sorafenib-resistant Liver Cancer Microenvironment by Using 3-D Spheroids. Alternatives to Laboratory Animals.
Crossref
Pengpeng Zhang, Tianyin Wang, Hong Liu, Xingguo She, Ke Chen, Yujun Zhao & Yingzi Ming. (2023) Acute rejection was observed in a combination therapy of CTLA-4 and PD-1 inhibitors before liver transplantation: A case report and literature review. iLIVER.
Crossref
Xiaofeng He, Wenjing Ma, Jing Hu, Tianze Li, Changan Geng, Yunbao Ma, Mengfei Wang, Kexin Yang, Xuemei Zhang & Ji-Jun Chen. (2023) Diverse structures and antihepatoma effect of sesquiterpenoid dimers from Artemisia eriopoda by AKT/STAT signaling pathway. Signal Transduction and Targeted Therapy 8:1.
Crossref
Johnny Amer, Ahmad Salhab, Nidal Jaradat, Samer Abdallah, Hanood Aburas, Suhaib Hattab, Mustafa Ghanim & Malik Alqub. (2022) Gundelia tournefortii inhibits hepatocellular carcinoma progression by lowering gene expression of the cell cycle and hepatocyte proliferation in immunodeficient mice. Biomedicine & Pharmacotherapy 156, pages 113885.
Crossref
Rui-Jie Sun, Dong-mei Yin, Dai Yuan, Shu-yan Liu, Jing-jing Zhu & Ning-ning Shan. (2021) Quantitative LC–MS/MS uncovers the regulatory role of autophagy in immune thrombocytopenia. Cancer Cell International 21:1.
Crossref
Roxana M. Rodríguez Stewart, Vishnu Raghuram, Jameson T. L. Berry, Gaurav N. Joshi & Bernardo A. Mainou. (2020) Noncanonical Cell Death Induction by Reassortant Reovirus. Journal of Virology 94:22.
Crossref
Beom Jin Lim, Woon-Kyu Lee, Hyun Woong Lee, Kwan Sik Lee, Ja Kyung Kim, Hye Young Chang & Jung Il Lee. (2018) Selective deletion of hepatocyte platelet-derived growth factor receptor α and development of liver fibrosis in mice. Cell Communication and Signaling 16:1.
Crossref
Weijun Wei, Dalong Ni, Emily B. Ehlerding, Quan-Yong Luo & Weibo Cai. (2018) PET Imaging of Receptor Tyrosine Kinases in Cancer. Molecular Cancer Therapeutics 17:8, pages 1625-1636.
Crossref
Jing Wang, Peng Sun, Yijun Chen, Hequan Yao & Shuzhen Wang. (2018) Novel 2-phenyloxypyrimidine derivative induces apoptosis and autophagy via inhibiting PI3K pathway and activating MAPK/ERK signaling in hepatocellular carcinoma cells. Scientific Reports 8:1.
Crossref
Chang Liu, Yi-Fan Ren, Jian Dong, Meng-Yun Ke, Feng Ma, Satdarshan P.S. Monga, Rongqian Wu, Yi Lv & Xu-Feng Zhang. (2017) Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma. Cancer Letters 410, pages 20-31.
Crossref
Veronika Malínková, Eva Řezníčková, Radek Jorda, Tomáš Gucký & Vladimír Kryštof. (2017) Trisubstituted purine inhibitors of PDGFRα and their antileukemic activity in the human eosinophilic cell line EOL-1. Bioorganic & Medicinal Chemistry 25:24, pages 6523-6535.
Crossref
Madhura Joglekar-Javadekar, Steven Van Laere, Michael Bourne, Manal Moalwi, Pascal Finetti, Peter B. Vermeulen, Daniel Birnbaum, Luc Y. Dirix, Naoto Ueno, Monique Carter, Justin Rains, Abhijit Ramachandran, Francois Bertucci & Kenneth L. van Golen. (2017) Characterization and Targeting of Platelet-Derived Growth Factor Receptor alpha (PDGFRA) in Inflammatory Breast Cancer (IBC). Neoplasia 19:7, pages 564-573.
Crossref
Renee G Sprundel, Ted SGAM Ingh, Baukje A Schotanus, Monique E Wolferen, Louis C Penning, Jan Rothuizen & Bart Spee. (2017) Cellular characteristics of keratin 19‐positive canine hepatocellular tumours explain its aggressive behaviour. Veterinary Record Open 4:1.
Crossref
Esther Ekpe-Adewuyi, Ana Lopez-Campistrous, Xiaoyun Tang, David N. Brindley & Todd P. W. McMullen. (2016) Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition. Oncotarget 7:50, pages 83684-83700.
Crossref
Ralf Weiskirchen. (2016) Hepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next Step. Frontiers in Pharmacology 6.
Crossref
Ian D. Connolly, Rohaid Ali, Yingmei Li & Melanie Hayden Gephart. (2015) Genetic and molecular distinctions in spinal ependymomas: A review. Clinical Neurology and Neurosurgery 139, pages 210-215.
Crossref
Olivier Govaere & Tania Roskams. (2015) Pathogenesis and Prognosis of Hepatocellular Carcinoma at the Cellular and Molecular Levels. Clinics in Liver Disease 19:2, pages 261-276.
Crossref
Franziska Mußbach, Petra Henklein, Martin Westermann, Utz Settmacher, Frank-D. Böhmer & Roland Kaufmann. (2014) Proteinase-activated receptor 1- and 4-promoted migration of Hep3B hepatocellular carcinoma cells depends on ROS formation and RTK transactivation. Journal of Cancer Research and Clinical Oncology 141:5, pages 813-825.
Crossref
Alexander Kikuchi & Satdarshan Pal Monga. (2015) PDGFRα in Liver Pathophysiology: Emerging Roles in Development, Regeneration, Fibrosis, and Cancer. Gene Expression 16:3, pages 109-127.
Crossref
Tao Wei, Li-Na Zhang, Yi Lv, Xiao-Ya Ma, Lei Zhi, Chang Liu, Feng Ma & Xu-Feng Zhang. (2014) Overexpression of platelet-derived growth factor receptor alpha promotes tumor progression and indicates poor prognosis in hepatocellular carcinoma. Oncotarget 5:21, pages 10307-10317.
Crossref
Ashley N. Davis, Vahid Afshar-Kharghan & Anil K. Sood. (2014) Platelet Effects on Ovarian Cancer. Seminars in Oncology 41:3, pages 378-384.
Crossref
Olivier Govaere, Mina Komuta, Johannes Berkers, Bart Spee, Carl Janssen, Francesca de Luca, Aezam Katoonizadeh, Jasper Wouters, Léon C van Kempen, Anne Durnez, Chris Verslype, Joery De Kock, Vera Rogiers, Leo A van Grunsven, Baki Topal, Jacques Pirenne, Hugo Vankelecom, Frederik Nevens, Joost van den Oord, Massimo Pinzani & Tania Roskams. (2014) Keratin 19: a key role player in the invasion of human hepatocellular carcinomas. Gut 63:4, pages 674-685.
Crossref
Zsolt Horváth, Ilona Kovalszky, Alexandra Fullár, Katalin Kiss, Zsuzsa Schaff, Renato V. Iozzo & Kornélia Baghy. (2014) Decorin deficiency promotes hepatic carcinogenesis. Matrix Biology 35, pages 194-205.
Crossref
Koji Matsuo, Masato Nishimura, Kakajan Komurov, Mian M.K. Shahzad, Rouba Ali-Fehmi, Ju-Won Roh, Chunhua Lu, Dianna D. Cody, Prahlad T. Ram, Nick Loizos, Robert L. Coleman & Anil K. Sood. (2014) Platelet-derived growth factor receptor alpha (PDGFRα) targeting and relevant biomarkers in ovarian carcinoma. Gynecologic Oncology 132:1, pages 166-175.
Crossref
Kornélia Baghy, Zsolt Horváth, Eszter Regős, Katalin Kiss, Zsuzsa Schaff, Renato V. Iozzo & Ilona Kovalszky. (2013) Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis. FEBS Journal 280:10, pages 2150-2164.
Crossref
Prince K. Awuah, Kari N. Nejak-Bowen & Satdarshan P.S. Monga. (2013) Role and Regulation of PDGFRα Signaling in Liver Development and Regeneration. The American Journal of Pathology 182:5, pages 1648-1658.
Crossref
Zhi-Lei LIU, Wei SUN, Fu-Chu HE, Xian-Ling CONG & Ying JIANG. (2012) Status and Development of The Tumor Microenvironment in Hepatocellular Carcinoma*. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 39:5, pages 416-422.
Crossref
Prince Kwaku Awuah, Byung Han Rhieu, Sucha Singh, Amalea Misse & Satdarshan P. S. Monga. (2012) β-Catenin Loss in Hepatocytes Promotes Hepatocellular Cancer after Diethylnitrosamine and Phenobarbital Administration to Mice. PLoS ONE 7:6, pages e39771.
Crossref
P. Martinez-Becerra, J. Vaquero, M. R. Romero, E. Lozano, C. Anadon, R. I. R. Macias, M. A. Serrano, N. Grañé-Boladeras, L. Muñoz-Bellvis, L. Alvarez, B. Sangro, M. Pastor-Anglada & J. J. G. Marin. (2012) No Correlation between the Expression of FXR and Genes Involved in Multidrug Resistance Phenotype of Primary Liver Tumors. Molecular Pharmaceutics 9:6, pages 1693-1704.
Crossref
Huan-You Wang, John A. Thorson, H. Elizabeth Broome, Hooman H. Rashidi, Peter T. Curtin & Marie L. Dell'Aquila. (2011) t(4;22)(q12;q11.2) involving presumptive platelet-derived growth factor receptor A and break cluster region in a patient with mixed phenotype acute leukemia. Human Pathology 42:12, pages 2029-2036.
Crossref
Sameer H. Patel, Peter J. Kneuertz, Maria Delgado, David A. Kooby, Charles A. StaleyIIIIII, Bassel F. El-Rayes, John S. Kauh, Juan M. Sarmiento, Steven Hanish, Cynthia Cohen, Alton B. FarrisIIIIII & Shishir K. Maithel. (2011) Clinically Relevant Biomarkers to Select Patients for Targeted Inhibitor Therapy after Resection of Hepatocellular Carcinoma. Annals of Surgical Oncology 18:12.
Crossref
Abigale Lade & Satdarshan P. S. Monga. 2011. Molecular Pathology of Liver Diseases. Molecular Pathology of Liver Diseases 291 306 .
Xu-Feng Zhang, Xinping Tan, Gang Zeng, Amalea Misse, Sucha Singh, Youngsoo Kim, James E. Klaunig & Satdarshan P. S. Monga. (2010) Conditional β-catenin loss in mice promotes chemical hepatocarcinogenesis: Role of oxidative stress and platelet-derived growth factor receptor α/phosphoinositide 3-kinase signaling. Hepatology 52:3, pages 954-965.
Crossref
Valerie N. Barton, Andrew M. Donson, Bette K. Kleinschmidt-DeMasters, Diane K. Birks, Michael H. Handler & Nicholas K. Foreman. (2010) Unique Molecular Characteristics of Pediatric Myxopapillary Ependymoma. Brain Pathology 20:3, pages 560-570.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.