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Kv1.3 potassium channels as a therapeutic target in multiple sclerosis

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Pages 909-924 | Published online: 20 Jun 2009

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Mireia Pérez-Verdaguer, Jesusa Capera, Clara Serrano-Novillo, Irene Estadella, Daniel Sastre & Antonio Felipe. (2016) The voltage-gated potassium channel Kv1.3 is a promising multitherapeutic target against human pathologies. Expert Opinion on Therapeutic Targets 20:5, pages 577-591.
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Neil A Castle. (2010) Pharmacological modulation of voltage-gated potassium channels as a therapeutic strategy. Expert Opinion on Therapeutic Patents 20:11, pages 1471-1503.
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Nóra Legány, Gergely Toldi, Csaba Orbán, Nóra Megyes, Anna Bajnok & Attila Balog. (2016) Calcium influx kinetics, and the features of potassium channels of peripheral lymphocytes in primary Sjögren’s syndrome. Immunobiology 221:11, pages 1266-1272.
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Soohyun Kwon, Frank Bosmans, Quentin Kaas, Olivier Cheneval, Anne C. Conibear, K. Johan Rosengren, Conan K. Wang, Christina I. Schroeder & David J. Craik. (2016) Efficient enzymatic cyclization of an inhibitory cystine knot‐containing peptide. Biotechnology and Bioengineering 113:10, pages 2202-2212.
Crossref
Marie-France Martin-Eauclaire, Adriano M.C. Pimenta, Pierre E. Bougis & Maria-Elena De Lima. (2016) Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus ( ). Toxicon 119, pages 253-265.
Crossref
Petra Ehling, Patrick Meuth, Paul Eichinger, Alexander M. Herrmann, Stefan Bittner, Matthias Pawlowski, Susann Pankratz, Michael Herty, Thomas Budde & Sven G. Meuth. (2016) Human T cells in silico: Modelling their electrophysiological behaviour in health and disease. Journal of Theoretical Biology 404, pages 236-250.
Crossref
Thomas M. Reeves, Patricia A. Trimmer, Beverly S. Colley & Linda L. Phillips. (2016) Targeting Kv1.3 channels to reduce white matter pathology after traumatic brain injury. Experimental Neurology 283, pages 188-203.
Crossref
B. Wu, B. F. Wu, Y. J. Feng, J. Tao & Y. H. Ji. (2016) Mapping the Interaction Anatomy of BmP02 on Kv1.3 Channel. Scientific Reports 6:1.
Crossref
Yuta Takahashi, Zhiqian Yu, Mai Sakai & Hiroaki Tomita. (2016) Linking Activation of Microglia and Peripheral Monocytic Cells to the Pathophysiology of Psychiatric Disorders. Frontiers in Cellular Neuroscience 10.
Crossref
Steve Peigneur, Yoko Yamaguchi, Chihiro Kawano, Takeru Nose, Selvanayagam Nirthanan, Ponnampalam Gopalakrishnakone, Jan Tytgat & Kazuki Sato. (2016) Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning. Biochemistry 55:21, pages 2927-2935.
Crossref
Ning Zhao, Qian Dong, Cheng Qian, Sen Li, Qiong-Feng Wu, Dan Ding, Jing Li, Bin-Bin Wang, Ke-fang Guo, Jiang-jiao Xie, Xiang Cheng, Yu-Hua Liao & Yi-Mei Du. (2015) Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties. Scientific Reports 5:1.
Crossref
Itsuro Kazama, Tsutomu Tamada & Masahiro Tachi. (2015) Usefulness of targeting lymphocyte Kv1.3-channels in the treatment of respiratory diseases. Inflammation Research 64:10, pages 753-765.
Crossref
Yu‐Ye Zhou, Guo‐Qiang Hou, Song‐Wei He, Zhuo Xiao, Hui‐Juan Xu, Ya‐Tao Qiu, Sheng Jiang, Hui Zheng & Zhi‐Yuan Li. (2015) Psora‐4, a Kv1.3 Blocker, Enhances Differentiation and Maturation in Neural Progenitor Cells. CNS Neuroscience & Therapeutics 21:7, pages 558-567.
Crossref
P Bhargava & P A Calabresi. (2015) Novel therapies for memory cells in autoimmune diseases. Clinical and Experimental Immunology 180:3, pages 353-360.
Crossref
Itsuro Kazama. (2015) Roles of Lymphocyte Kv1.3-Channels in the Pathogenesis of Renal Diseases and Novel Therapeutic Implications of Targeting the Channels. Mediators of Inflammation 2015, pages 1-12.
Crossref
Itsuro Kazama. (2014) Physiological significance of delayed rectifier K+ channels (Kv1.3) expressed in T lymphocytes and their pathological significance in chronic kidney disease. The Journal of Physiological Sciences 65:1, pages 25-35.
Crossref
Duane Moogk, Ines Pires da Silva, Michelle W Ma, Erica B Friedman, Eleazar Vega-Saenz de Miera, Farbod Darvishian, Patrick Scanlon, Arianne Perez-Garcia, Anna C Pavlick, Nina Bhardwaj, Paul J Christos, Iman Osman & Michelle Krogsgaard. (2014) Melanoma expression of matrix metalloproteinase-23 is associated with blunted tumor immunity and poor responses to immunotherapy. Journal of Translational Medicine 12:1.
Crossref
Rong Chen & Shin-Ho Chung. (2014) Binding Modes of Two Scorpion Toxins to the Voltage-Gated Potassium Channel Kv1.3 Revealed from Molecular Dynamics. Toxins 6:7, pages 2149-2161.
Crossref
Tadashi Katoh. 2014. 1 39 .
Albert Vallejo-Gracia, Joanna Bielanska, Javier Hernández-Losa, Josep Castellví, M Carmen Ruiz-Marcellan, Santiago Ramón y Cajal, Enric Condom, Joan Manils, Concepció Soler, Núria Comes, Joan Carles Ferreres & Antonio Felipe. (2013) Emerging role for the voltage-dependent K+ channel Kv1.5 in B-lymphocyte physiology: expression associated with human lymphoma malignancy. Journal of Leukocyte Biology 94:4, pages 779-789.
Crossref
Yi‐Tian Lian, Xiao‐Fang Yang, Zhao‐Hui Wang, Yong Yang, Ying Yang, Yan‐Wen Shu, Long‐Xian Cheng & Kun Liu. (2012) Curcumin Serves as a Human Kv1.3 Blocker to Inhibit Effector Memory T Lymphocyte Activities. Phytotherapy Research 27:9, pages 1321-1327.
Crossref
Ning Zhao, Qian Dong, Li-Li Du, Xiao-Xing Fu, Yi-Mei Du & Yu-Hua Liao. (2013) Potent Suppression of Kv1.3 Potassium Channel and IL-2 Secretion by Diphenyl Phosphine Oxide-1 in Human T Cells. PLoS ONE 8:5, pages e64629.
Crossref
Yong Yang, Yan-Fu Wang, Xiao-Fang Yang, Zhao-Hui Wang, Yi-Tian Lian, Ying Yang, Xiao-Wei Li, Xiang Gao, Jian Chen, Yan-Wen Shu, Long-Xian Cheng, Yu-Hua Liao & Kun Liu. (2013) Specific Kv1.3 blockade modulates key cholesterol-metabolism-associated molecules in human macrophages exposed to ox-LDL. Journal of Lipid Research 54:1, pages 34-43.
Crossref
Niels Decher, Michael F. Netter & Anne K. Streit. (2012) Putative Impact of RNA Editing on Drug Discovery. Chemical Biology & Drug Design 81:1, pages 13-21.
Crossref
Raveendra Anangi, Shyny Koshy, Redwan Huq, Christine Beeton, Woei-Jer Chuang & Glenn F. King. (2012) Recombinant Expression of Margatoxin and Agitoxin-2 in Pichia pastoris: An Efficient Method for Production of KV1.3 Channel Blockers. PLoS ONE 7:12, pages e52965.
Crossref
Eric J. Tarcha, Victor Chi, Ernesto J. Muñoz-Elías, David Bailey, Luz M. Londono, Sanjeev K. Upadhyay, Kayla Norton, Amy Banks, Indra Tjong, Hai Nguyen, Xueyou Hu, Greg W. Ruppert, Scott E. Boley, Richard Slauter, James Sams, Brian Knapp, Dustin Kentala, Zachary Hansen, Michael W. Pennington, Christine Beeton, K. George Chandy & Shawn P. Iadonato. (2012) Durable Pharmacological Responses from the Peptide ShK-186, a Specific Kv1.3 Channel Inhibitor That Suppresses T Cell Mediators of Autoimmune Disease. Journal of Pharmacology and Experimental Therapeutics 342:3, pages 642-653.
Crossref
Zhi Li, Wan-Hong Liu, Song Han, Bi-Wen Peng, Jun Yin, Ying-Liang Wu, Xiao-Hua He & Wen-Xin Li. (2012) Selective Inhibition of CCR7− Effector Memory T Cell Activation by a Novel Peptide Targeting Kv1.3 Channel in a Rat Experimental Autoimmune Encephalomyelitis Model. Journal of Biological Chemistry 287:35, pages 29479-29494.
Crossref
Carlos González, David Baez‐Nieto, Ignacio Valencia, Ingrid Oyarzún, Patricio Rojas, David Naranjo & Ramón Latorre. 2011. Comprehensive Physiology. Comprehensive Physiology 2087 2149 .
Xiao-Fang Yang, Yong Yang, Yi-Tian Lian, Zhao-Hui Wang, Xiao-Wei Li, Long-Xian Cheng, Jin-Ping Liu, Yan-Fu Wang, Xiang Gao, Yu-Hua Liao, Min Wang, Qiu-Tang Zeng & Kun Liu. (2012) The Antibody Targeting the E314 Peptide of Human Kv1.3 Pore Region Serves as a Novel, Potent and Specific Channel Blocker. PLoS ONE 7:4, pages e36379.
Crossref
Xueyou Hu, Teresina Laragione, Liang Sun, Shyny Koshy, Karlie R. Jones, Iskander I. Ismailov, Patricia Yotnda, Frank T. Horrigan, Pércio S. Gulko & Christine Beeton. (2012) KCa1.1 Potassium Channels Regulate Key Proinflammatory and Invasive Properties of Fibroblast-like Synoviocytes in Rheumatoid Arthritis. Journal of Biological Chemistry 287:6, pages 4014-4022.
Crossref
Li-Hua Wang, Ning Wang, Xiao-Yu Lu, Bing-Chen Liu, Murali K. Yanda, John Z. Song, Helena M. Dai, Yu-Liang Sun, Hui-Fang Bao, Douglas C. Eaton & He-Ping Ma. (2012) Rituximab inhibits Kv1.3 channels in human B lymphoma cells via activation of FcγRIIB receptors. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:2, pages 505-513.
Crossref
Petra Ehling, Stefan Bittner, Thomas Budde, Heinz Wiendl & Sven G. Meuth. (2011) Ion channels in autoimmune neurodegeneration. FEBS Letters 585:23, pages 3836-3842.
Crossref
Tom Schilling & Claudia Eder. (2011) Amyloid-β-induced reactive oxygen species production and priming are differentially regulated by ion channels in microglia. Journal of Cellular Physiology 226:12, pages 3295-3302.
Crossref
Gergely Toldi, András Folyovich, Zsuzsa Simon, Katalin Zsiga, Ambrus Kaposi, Gergő Mészáros, Tivadar Tulassay & Barna Vásárhelyi. (2011) Lymphocyte calcium influx kinetics in multiple sclerosis treated without or with interferon beta. Journal of Neuroimmunology 237:1-2, pages 80-86.
Crossref
Alex Cheong, Jing Li, Piruthivi Sukumar, Bhaskar Kumar, Fanning Zeng, Kirsten Riches, Christopher Munsch, Ian C. Wood, Karen E. Porter & David J. Beech. (2011) Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers. Cardiovascular Research 89:2, pages 282-289.
Crossref
Soo Hwa JangPan Dong RyuSo Yeong Lee. (2011) Dendrotoxin-κ suppresses tumor growth induced by human lung adenocarcinoma A549 cells in nude mice. Journal of Veterinary Science 12:1, pages 35.
Crossref
Supa Hannongbua, Witcha Treesuwan & Warabhorn Boonyarat. 2011. Ion Channels and Their Inhibitors. Ion Channels and Their Inhibitors 53 78 .
Jian Ma, Christie‐Ann McCarl, Sara Khalil, Kevin Lüthy & Stefan Feske. (2010) T‐cell‐specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cells. European Journal of Immunology 40:11, pages 3028-3042.
Crossref
Claudia Eder. (2010) Ion channels in monocytes and microglia / brain macrophages: Promising therapeutic targets for neurological diseases. Journal of Neuroimmunology 224:1-2, pages 51-55.
Crossref
Russell W Teichert & Baldomero M Olivera. (2010) Natural products and ion channel pharmacology. Future Medicinal Chemistry 2:5, pages 731-744.
Crossref
Conor McCloskey, Sarah Jones, Stefan Amisten, Roger T. Snowden, Leonard K. Kaczmarek, David Erlinge, Alison H. Goodall, Ian D. Forsythe & Martyn P. Mahaut-Smith. (2010) Kv1.3 is the exclusive voltage-gated K + channel of platelets and megakaryocytes: roles in membrane potential, Ca 2+ signalling and platelet count . The Journal of Physiology 588:9, pages 1399-1406.
Crossref

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