Advanced search
Publication Cover
Expert Opinion on Therapeutic Targets Volume 13, 2009 - Issue 9
Submit an article Journal homepage
254
Views
17
CrossRef citations to date
0
Altmetric
Perspective

RNA interference screening for the discovery of oncology targets

Kim Quon Amgen, Inc., Oncology Department, AW2-D2262, 1201 Amgen Court West, Seattle, WA 98119-3105, USA +1 206 265 8214; +1 206 217 0494; [email protected]
&
Paul D Kassner Amgen, Inc., Lead Discovery Department, ASF1-2122, 1120 Veterans Boulevard, South San Francisco, CA 94080, USA +1 650 244 2184; +1 650 837 9373; [email protected]
Pages 1027-1035 | Published online: 04 Aug 2009

Citations (17)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Xiangyang Zhang, Bin Qin, Min Wang, Junyi Feng, Chenglin Zhang, Chengshen Zhu, Suqin He, Hao Liu, Yaohe Wang, Saadyah E Averick, Nga T N Vo, Lei Huang, Wentao Liu & Zhimin Wang. (2022) Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment. International Journal of Nanomedicine 17, pages 953-967.
Read now

Articles from other publishers (16)

Yaimeé Vázquez‐Mojena, Karen León‐Arcia, Yanetza González‐Zaldivar, Roberto Rodríguez‐Labrada & Luis Velázquez‐Pérez. (2021) Gene Therapy for Polyglutamine Spinocerebellar Ataxias: Advances, Challenges, and Perspectives. Movement Disorders 36:12, pages 2731-2744.
Crossref
Mei Ding, Christian Tyrchan, Elisabeth Bäck, Jörgen Östling, Steffen Schubert & Christopher McCrae. (2020) Combined siRNA and Small-Molecule Phenotypic Screening Identifies Targets Regulating Rhinovirus Replication in Primary Human Bronchial Epithelial Cells. SLAS Discovery 25:6, pages 634-645.
Crossref
William Ho, Xue-Qing Zhang & Xiaoyang Xu. (2016) Biomaterials in siRNA Delivery: A Comprehensive Review. Advanced Healthcare Materials 5:21, pages 2715-2731.
Crossref
Jesús R. Medina. (2013) Selective 3-Phosphoinositide-Dependent Kinase 1 (PDK1) Inhibitors: Dissecting the Function and Pharmacology of PDK1. Journal of Medicinal Chemistry 56:7, pages 2726-2737.
Crossref
Gerard Drewes. (2012) Future strategies in epigenetic drug discovery. Drug Discovery Today: Therapeutic Strategies 9:2-3, pages e121-e127.
Crossref
Christopher Alabi, Arturo Vegas & Daniel Anderson. (2012) Attacking the genome: emerging siRNA nanocarriers from concept to clinic. Current Opinion in Pharmacology 12:4, pages 427-433.
Crossref
Debmalya Barh, Shoaib Ahmad & Atanu Bhattacharjee. 2012. Pharmaceutical Biotechnology. Pharmaceutical Biotechnology 451 490 .
Swen Hoelder, Paul A. Clarke & Paul Workman. (2012) Discovery of small molecule cancer drugs: Successes, challenges and opportunities. Molecular Oncology 6:2, pages 155-176.
Crossref
E Ji-Fu, Jun-Jie Xing, Li-Qiang Hao & Chuan-Gang Fu. (2011) Suppression of lung cancer metastasis-related protein 1 (LCMR1) inhibits the growth of colorectal cancer cells. Molecular Biology Reports 39:4, pages 3675-3681.
Crossref
Gregory Landes & Kathleen Elias. 2012. Development of Antibody-Based Therapeutics. Development of Antibody-Based Therapeutics 183 240 .
Attila A. Seyhan. (2011) RNAi: a potential new class of therapeutic for human genetic disease. Human Genetics 130:5, pages 583-605.
Crossref
Inmaculada Posadas, Francisco Javier Guerra & Valentín Ceña. (2010) Nonviral vectors for the delivery of small interfering RNAs to the CNS. Nanomedicine 5:8, pages 1219-1236.
Crossref
Xiaohua Douglas Zhang, Raul Lacson, Ruojing Yang, Shane D. Marine, Alex McCampbell, Dawn M. Toolan, Tim R. Hare, Joleen Kajdas, Joel P. Berger, Daniel J. Holder, Joseph F. Heyse & Marc Ferrer. (2010) The Use of SSMD-Based False Discovery and False Nondiscovery Rates in Genome-Scale RNAi Screens. SLAS Discovery 15:9, pages 1123-1131.
Crossref
Shilpi Arora, Kristen M. Bisanz, Lourdes A. Peralta, Gargi D. Basu, Ashish Choudhary, Raoul Tibes & David O. Azorsa. (2010) RNAi screening of the kinome identifies modulators of cisplatin response in ovarian cancer cells. Gynecologic Oncology 118:3, pages 220-227.
Crossref
Andrew M. Smith, Ron Ammar, Corey Nislow & Guri Giaever. (2010) A survey of yeast genomic assays for drug and target discovery. Pharmacology & Therapeutics 127:2, pages 156-164.
Crossref
JING-YI YUAN, LI-YING LIU, PEI WANG, ZONG-FANG LI, LEI NI, AIYING WANG, SHENG-XIANG XIAO, TU-SHENG SONG & CHEN HUANG. (2010) Small-interfering RNA-mediated silencing of the MAPK p42 gene induces dual effects in HeLa cells. Oncology Letters 1:4, pages 649-655.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.