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Expert Opinion on Therapeutic Targets Volume 11, 2007 - Issue 2
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Review

The role of renin–angiotensin system inhibition in the treatment of hypertension in metabolic syndrome: are all the angiotensin receptor blockers equal?

Asterios Karagiannis Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
,
Dimitri P Mikhailidis Department of Clinical Biochemistry (Vascular Prevention Clinic), Royal Free Hospital, Royal Free and University College Medical School (University of London), Pond Street, London, NW3 2QG, UK. [email protected]
,
Vasilios G Athyros Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
,
Anna I Kakafika Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece; Department of Clinical Biochemistry (Vascular Prevention Clinic), Royal Free Hospital, Royal Free and University College Medical School (University of London), Pond Street, London, NW3 2QG, UK. [email protected]
,
Konstantinos Tziomalos Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
,
Evangelos N Liberopoulos Department of Internal Medicine, Medical School, University of Ioannina, Greece
,
Matilda Florentin Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
&
Moses Elisaf Department of Internal Medicine, Medical School, University of Ioannina, Greece
 show all
Pages 191-205 | Published online: 17 Jan 2007

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Gabriele Fragasso, Francesco Maranta, Claudia Montanaro, Anna Salerno, Camilla Torlasco & Alberto Margonato. (2012) Pathophysiologic therapeutic targets in hypertension: a cardiological point of view. Expert Opinion on Therapeutic Targets 16:2, pages 179-193.
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Vassilios G. Athyros, Asterios Karagiannis, Emmanouel S. Ganotakis, Konstantinos Paletas, Vassilios Nicolaou, George Bacharoudis, Konstantinos Tziomalos, Theodore Alexandrides, Evangelos N. Liberopoulos & Dimitri P. Mikhailidis. (2011) Association between the changes in renal function and serum uric acid levels during multifactorial intervention and clinical outcome in patients with metabolic syndrome. A post hoc analysis of the ATTEMPT study. Current Medical Research and Opinion 27:8, pages 1659-1668.
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V. G. Athyros, A. Karagiannis, A. I. Hatzitolios, K. Paletas, C. Savopoulos, G. Giannoglou & D. P. Mikhailidis. (2009) Standardized arrangement for a guideline-driven treatment of the metabolic syndrome: the SAGE-METS study. Current Medical Research and Opinion 25:4, pages 971-980.
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Keith Suckling. (2007) Drug discovery in the metabolic syndrome: context and some recent developments. Expert Opinion on Therapeutic Targets 11:6, pages 801-808.
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Alexandra Katsimardou, Konstantinos Imprialos, Konstantinos Stavropoulos, Alexandros Sachinidis, Michalis Doumas & Vasilios Athyros. (2020) Hypertension in Metabolic Syndrome: Novel Insights. Current Hypertension Reviews 16:1, pages 12-18.
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Subhadeep Chakrabarti, Forough Jahandideh, Sandra T Davidge & Jianping Wu. (2018) Milk-Derived Tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) Enhance Insulin Sensitivity and Prevent Insulin Resistance in 3T3-F442A Preadipocytes. Journal of Agricultural and Food Chemistry 66:39, pages 10179-10187.
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Mona Schaalan, Waleed Mohamed & Rania Rahmo. (2016) Association of cardiac NT pro-β-type natriuretic peptide with metabolic and endothelial risk factors in young obese hypertensive patients: a perspective on the hypothalamic pituitary adrenal axis activation. Diabetology & Metabolic Syndrome 8:1.
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Marc J. Mathews, Edward H. Mathews & Leon Liebenberg. (2015) The mechanisms by which antidepressants may reduce coronary heart disease risk. BMC Cardiovascular Disorders 15:1.
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Subhadeep Chakrabarti & Jianping Wu. (2015) Milk-Derived Tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) Promote Adipocyte Differentiation and Inhibit Inflammation in 3T3-F442A Cells. PLOS ONE 10:2, pages e0117492.
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Vassilios G. Athyros, Moses S. Elisaf, Theodore Alexandrides, Apostolos Achimastos, Emmanouel Ganotakis, Eleni Bilianou, Asterios Karagiannis, Evangelos N. Liberopoulos, Konstantinos Tziomalos & Dimitri P. Mikhailidis. (2011) Long-Term Impact of Multifactorial Treatment on New-Onset Diabetes and Related Cardiovascular Events in Metabolic Syndrome. Angiology 63:5, pages 358-366.
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Kelly Putnam, Robin Shoemaker, Frederique Yiannikouris & Lisa A. Cassis. (2012) The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome. American Journal of Physiology-Heart and Circulatory Physiology 302:6, pages H1219-H1230.
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Joel Handler. (2010) Managing Hypertensive Patients With Gout Who Take Thiazide. The Journal of Clinical Hypertension 12:9, pages 731-735.
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David SiegelM.D., M.P.M.D., M.P. & Arthur L.M. SwislockiM.D.M.D.. (2010) Hypertensive Treatment in Patients With Metabolic Syndrome. Metabolic Syndrome and Related Disorders 8:2, pages 95-104.
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Panagiotis Anagnostis, Vasilios G. Athyros, Konstantinos Tziomalos, Asterios Karagiannis & Dimitri P. Mikhailidis. (2009) The Pathogenetic Role of Cortisol in the Metabolic Syndrome: A Hypothesis. The Journal of Clinical Endocrinology & Metabolism 94:8, pages 2692-2701.
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Yong-Qi LiHui JiYang ShenLi-Ju DingPei ZhuangYu-Lin YangQiu-Ju Huang. (2009) Chronic treatment with angiotensin AT 1 receptor antagonists reduced serum but not bone TGF-β 1 levels in ovariectomized rats . Canadian Journal of Physiology and Pharmacology 87:1, pages 51-55.
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Harry G. Preuss, Bobby Echard, Debasis Bagchi, Nicholas V. Perricone & Eiji Yamashita. (2009) Astaxanthin lowers blood pressure and lessens the activity of the renin-angiotensin system in Zucker Fatty Rats. Journal of Functional Foods 1:1, pages 13-22.
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Silvana Cianchetti, Alessandra Del Fiorentino, Renato Colognato, Rossella Di Stefano, Ferdinando Franzoni & Roberto Pedrinelli. (2008) Anti-inflammatory and anti-oxidant properties of telmisartan in cultured human umbilical vein endothelial cells. Atherosclerosis 198:1, pages 22-28.
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Evangelos C. Rizos, Athanasia Spyrou, Evangelos N. Liberopoulos, Eleni C. Papavasiliou, Vasilis Saougos, Alexandros D. Tselepis & Moses Elisaf. (2007) Effects of Eprosartan on Serum Metabolic Parameters in Patients with Essential Hypertension. The Open Cardiovascular Medicine Journal 1:1, pages 22-26.
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David Siegel & Arthur L.M. Swislocki. (2007) Effects of Antihypertensives on Glucose Metabolism. Metabolic Syndrome and Related Disorders 5:3, pages 211-219.
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