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Review

Targeting angiogenin in therapy of amyotropic lateral sclerosis

, & , PhD
Pages 1229-1242 | Published online: 09 Sep 2008

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Aditya K. Padhi, Priyam Narain, Upma Dave, Rohit Satija, Anirudh Patir & James Gomes. (2019) Insights into the role of ribonuclease 4 polymorphisms in amyotrophic lateral sclerosis. Journal of Biomolecular Structure and Dynamics 37:1, pages 116-130.
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Articles from other publishers (34)

Di He, Yan Xu, Mingsheng Liu & Liying Cui. (2023) The Inflammatory Puzzle: Piecing together the Links between Neuroinflammation and Amyotrophic Lateral Sclerosis. Aging and disease, pages 0.
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Ilaria Giovannelli, Adrian Higginbottom, Janine Kirby, Mimoun Azzouz & Pamela J. Shaw. (2022) Prospects for gene replacement therapies in amyotrophic lateral sclerosis. Nature Reviews Neurology 19:1, pages 39-52.
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Florian Pichot, Marion C. Hogg, Virginie Marchand, Valérie Bourguignon, Elisabeth Jirström, Cliona Farrell, Hesham A. Gibriel, Jochen H.M. Prehn, Yuri Motorin & Mark Helm. (2023) Quantification of substoichiometric modification reveals global tsRNA hypomodification, preferences for angiogenin-mediated tRNA cleavage, and idiosyncratic epitranscriptomes of human neuronal cell-lines. Computational and Structural Biotechnology Journal 21, pages 401-417.
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Jie Zhang, An Wen, Wen Chai, Huiting Liang, Chunyan Tang, Weiming Gan & Renshi Xu. (2022) Potential proteomic alteration in the brain of Tg(SOD1*G93A)1Gur mice: A new pathogenesis insight of amyotrophic lateral sclerosis. Cell Biology International 46:9, pages 1378-1398.
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Rosanna Culurciello, Andrea Bosso, Romualdo Troisi, Valentina Barrella, Ilaria Di Nardo, Margherita Borriello, Rosa Gaglione, Valeria Pistorio, Serena Aceto, Valeria Cafaro, Eugenio Notomista, Filomena Sica, Angela Arciello & Elio Pizzo. (2022) Protective Effects of Recombinant Human Angiogenin in Keratinocytes: New Insights on Oxidative Stress Response Mediated by RNases. International Journal of Molecular Sciences 23:15, pages 8781.
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Haihua Tian, Zhenyu Hu & Chuang Wang. (2022) The Therapeutic Potential of tRNA-derived Small RNAs in Neurodegenerative Disorders. Aging and disease 13:2, pages 389.
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Giovanni Tabbì, Lorena Maria Cucci, Calogero Pinzino, Alessia Munzone, Tiziano Marzo, Silvia Pizzanelli, Cristina Satriano, Antonio Magrì & Diego La Mendola. (2021) Peptides Derived from Angiogenin Regulate Cellular Copper Uptake. International Journal of Molecular Sciences 22:17, pages 9530.
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Aditya K. Padhi, Rohit Shukla, Priyam Narain & James Gomes. (2021) A distant angiogenin variant causes amyotrophic lateral sclerosis through loss-of-function mechanisms: Insights from long-timescale atomistic simulations and conformational dynamics. Computers in Biology and Medicine 135, pages 104602.
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Prasanta Patra, Pratik Ghosh, Bidhan Chandra Patra & Manojit Bhattacharya. (2019) Biocomputational Analysis and In Silico Characterization of an Angiogenic Protein (RNase5) in Zebrafish (Danio rerio). International Journal of Peptide Research and Therapeutics 26:4, pages 1687-1697.
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Su Min Sung, Soo Jin Lee, Kyoo Won Lee & Jae Chan Kim. (2020) Ultraviolet B-induced Senescence Model Using Corneal Fibroblasts and the Anti-aging Effect of Angiogenin. Journal of the Korean Ophthalmological Society 61:9, pages 1015-1022.
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Krishna C. Aluri, Joseph P. Salisbury, Jochen H. M. Prehn & Jeffrey N. Agar. (2020) Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration. Scientific Reports 10:1.
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Heng-Huan Lee, Ying-Nai Wang & Mien-Chie Hung. (2019) Functional roles of the human ribonuclease A superfamily in RNA metabolism and membrane receptor biology. Molecular Aspects of Medicine 70, pages 106-116.
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Ying-Nai Wang, Heng-Huan Lee & Mien-Chie Hung. (2018) A novel ligand-receptor relationship between families of ribonucleases and receptor tyrosine kinases. Journal of Biomedical Science 25:1.
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Priyam Narain, Ashutosh Pandey, Shruti Gupta, James Gomes, Rohit Bhatia & Perumal Vivekanandan. (2018) Targeted next-generation sequencing reveals novel and rare variants in Indian patients with amyotrophic lateral sclerosis. Neurobiology of Aging 71, pages 265.e9-265.e14.
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Jie Zhang, Huiting Liang, Lei Zhu, Weiming Gan, Chunyan Tang, Jiao Li & Renshi Xu. (2017) Expression and Distribution of Arylsulfatase B are Closely Associated with Neuron Death in SOD1 G93A Transgenic Mice. Molecular Neurobiology 55:2, pages 1323-1337.
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Antonio Magrì, Giovanni Tabbì, Raffaella Breglia, Luca De Gioia, Piercarlo Fantucci, Maurizio Bruschi, Raffaele P. Bonomo & Diego La Mendola. (2017) Copper ion interaction with the RNase catalytic site fragment of the angiogenin protein: an experimental and theoretical investigation. Dalton Transactions 46:26, pages 8524-8538.
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Demetra S. M. Chatzileontiadou, Vicky G. Tsirkone, Kyriaki Dossi, Aikaterini G. Kassouni, Panagiota G. V. Liggri, Anastassia L. Kantsadi, George A. Stravodimos, Nikolaos A. A. Balatsos, Vassiliki T. Skamnaki & Demetres D. Leonidas. (2016) The ammonium sulfate inhibition of human angiogenin. FEBS Letters 590:17, pages 3005-3018.
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D. La Mendola, F. Arnesano, ?. Hansson, C. Giacomelli, V. Cal?, V. Mangini, A. Magr?, F. Bellia, M. L. Trincavelli, C. Martini, G. Natile & E. Rizzarelli. (2016) Copper binding to naturally occurring, lactam form of angiogenin differs from that to recombinant protein, affecting their activity. Metallomics 8:1, pages 118-124.
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Mridusmita Saikia & Maria Hatzoglou. (2015) The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health. Journal of Biological Chemistry 290:50, pages 29761-29768.
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Christian Cremer, Grit Hehmann-Titt, Sonja Schiffer, Georg Melmer, Paolo Carloni, Stefan Barth & Thomas Nachreiner. 2015. Resistance to Immunotoxins in Cancer Therapy. Resistance to Immunotoxins in Cancer Therapy 185 219 .
Suhas V Vasaikar, Aditya K Padhi, Bhyravabhotla Jayaram & James Gomes. (2013) NeuroDNet - an open source platform for constructing and analyzing neurodegenerative disease networks. BMC Neuroscience 14:1.
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Giovanni Nardo, Raffaele Iennaco, Nicolò Fusi, Paul R. Heath, Marianna Marino, Maria C. Trolese, Laura Ferraiuolo, Neil Lawrence, Pamela J. Shaw & Caterina Bendotti. (2013) Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis. Brain 136:11, pages 3305-3332.
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J. Kirby, J. R. Highley, L. Cox, E. F. Goodall, C. Hewitt, J. A. Hartley, H. C. Hollinger, M. Fox, P. G. Ince, C. J. McDermott & P. J. Shaw. (2013) Lack of unique neuropathology in amyotrophic lateral sclerosis associated with p.K54E angiogenin ( ANG ) mutation . Neuropathology and Applied Neurobiology 39:5, pages 562-571.
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Aditya K. Padhi, Suhas V. Vasaikar, Bhyravabhotla Jayaram & James Gomes. (2013) Fast prediction of deleterious angiogenin mutations causing amyotrophic lateral sclerosis. FEBS Letters 587:12, pages 1762-1766.
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Aditya K. Padhi, Bhyravabhotla Jayaram & James Gomes. (2013) Prediction of Functional Loss of Human Angiogenin Mutants Associated with ALS by Molecular Dynamics Simulations. Scientific Reports 3:1.
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Aditya K Padhi, Suhas V Vasaikar, Bhyravabhotla Jayaram & James Gomes. (2014) ANGDelMut – a web-based tool for predicting and analyzing functional loss mechanisms of amyotrophic lateral sclerosis-associated angiogenin mutations. F1000Research 2, pages 227.
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Aditya K Padhi, Suhas V Vasaikar, Bhyravabhotla Jayaram & James Gomes. (2013) ANGDelMut – a web-based tool for predicting and analyzing functional loss mechanisms of deleterious angiogenin mutations causing amyotrophic lateral sclerosis. F1000Research 2, pages 227.
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Mridusmita Saikia, Dawid Krokowski, Bo-Jhih Guan, Pavel Ivanov, Marc Parisien, Guo-fu Hu, Paul Anderson, Tao Pan & Maria Hatzoglou. (2012) Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress. Journal of Biological Chemistry 287:51, pages 42708-42725.
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Nethaji Thiyagarajan, Ross Ferguson, Vasanta Subramanian & K. Ravi Acharya. (2012) Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons. Nature Communications 3:1.
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Mikhail G. Pyatibratov & Alla S. Kostyukova. 2012. 175 198 .
Elio Pizzo, Antonello Merlino, Mimmo Turano, Irene Russo Krauss, Francesca Coscia, Anna Zanfardino, Mario Varcamonti, Adriana Furia, Concetta Giancola, Lelio Mazzarella, Filomena Sica & Giuseppe D'Alessio. (2010) A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish. Biochemical Journal 433:2, pages 345-355.
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Salvatore Sorrentino. (2010) The eight human “canonical” ribonucleases: Molecular diversity, catalytic properties, and special biological actions of the enzyme proteins. FEBS Letters 584:11, pages 2194-2200.
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Daria M. Monti, Wenhao Yu, Elio Pizzo, Kaori Shima, Miaofen G. Hu, Chiara Di Malta, Renata Piccoli, Giuseppe D’Alessio & Guo-Fu Hu. (2009) Characterization of the angiogenic activity of zebrafish ribonucleases. FEBS Journal 276:15, pages 4077-4090.
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Kimberly A. Dickson, Dong-Ku Kang, Young Sam Kwon, Jae Chan Kim, Peter A. Leland, Byung-Moon Kim, Soo-Ik Chang & Ronald T. Raines. (2009) Ribonuclease Inhibitor Regulates Neovascularization by Human Angiogenin. Biochemistry 48:18, pages 3804-3806.
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