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Protein kinase C isozymes as potential therapeutic targets in immune disorders

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Pages 535-552 | Published online: 15 Apr 2008

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Laura J Vella, Miles C Andrews, Andreas Behren, Jonathan Cebon & Katherine Woods. (2014) Immune consequences of kinase inhibitors in development, undergoing clinical trials and in current use in melanoma treatment. Expert Review of Clinical Immunology 10:8, pages 1107-1123.
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Hartwig P. Huemer, Markus Geiger, Wilfried Posch, Nina Krumböck, Friedrich Fresser, Doris Wilflingseder & Florian Überall. (2013) Protein Kinase C Overexpression Does Not Enhance Immune-Stimulatory Surface Markers of Vaccinia-Infected Dendritic Cells and DC Cell Lines. Immunological Investigations 42:2, pages 164-177.
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Articles from other publishers (21)

Sergiy A. Starosyla, Galyna P. Volynets, Mykola V. Protopopov, Volodymyr G. Bdzhola, Denis O. Pashevin, Valentyna O. Polishchuk, Taisiia O. Kozak, Dmytro O. Stroi, Victor E. Dosenko & Sergiy M. Yarmoluk. (2022) Pharmacophore modeling, docking and molecular dynamics simulation for identification of novel human protein kinase C beta (PKCβ) inhibitors. Structural Chemistry 34:3, pages 1157-1171.
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Taian Liu, Yujian Shi, Matthew T. V. Chan, Gang Peng, Quan Zhang, Xiao Sun, Zeyao Zhu, Yuxin Xie, Kathy W. Y. Sham, Jianzhen Li, Xiaodong Liu, Idy H. T. Ho, Tony Gin, Zhonghua Lu, William K. K. Wu & Christopher H. K. Cheng. (2018) Developmental protein kinase C hyper-activation results in microcephaly and behavioral abnormalities in zebrafish. Translational Psychiatry 8:1.
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Marion F. Haug, Matthias Gesemann, Manuela Berger & Stephan C. F. Neuhauss. (2018) Phylogeny and distribution of protein kinase C variants in the zebrafish. Journal of Comparative Neurology 526:7, pages 1097-1109.
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Bálint Botz, Kata Bölcskei & Zsuzsanna Helyes. (2016) Challenges to develop novel anti‐inflammatory and analgesic drugs. WIREs Nanomedicine and Nanobiotechnology 9:3.
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Maurice J. van Eis, JeanPierre Evenou, Walter Schuler, Gerhard Zenke, Eric Vangrevelinghe, Juergen Wagner & Peter von Matt. (2017) Indolyl-naphthyl-maleimides as potent and selective inhibitors of protein kinase C-α/β. Bioorganic & Medicinal Chemistry Letters 27:4, pages 781-786.
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Pierre-Luc Boudreault, Jennifer K. Mattler & Paul A. Wender. (2015) Studies on the regio- and diastereo-selective epoxidation of daphnanes and tiglianes. Tetrahedron Letters 56:23, pages 3423-3427.
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Jeong-Hun Kang. (2014) Protein Kinase C (PKC) Isozymes and Cancer. New Journal of Science 2014, pages 1-36.
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Eeva Moilanen. (2014) Two Faces of Inflammation: An Immunopharmacological View. Basic & Clinical Pharmacology & Toxicology 114:1, pages 2-6.
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Tiina Leppänen, Raimo K. Tuominen & Eeva Moilanen. (2014) Protein Kinase C and its Inhibitors in the Regulation of Inflammation: Inducible Nitric Oxide Synthase as an Example. Basic & Clinical Pharmacology & Toxicology 114:1, pages 37-43.
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Tapan Saha, Ratnava Maitra & Shital K Chattopadhyay. (2013) A unified approach to the important protein kinase inhibitor balanol and a proposed analogue. Beilstein Journal of Organic Chemistry 9, pages 2910-2915.
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Daniel M. Tremmel, Sedat Resad, Christopher J. Little & Cedric S. Wesley. (2013) Notch and PKC Are Involved in Formation of the Lateral Region of the Dorso-Ventral Axis in Drosophila Embryos. PLoS ONE 8:7, pages e67789.
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Tiina Leppänen, Riku Korhonen, Mirka Laavola, Riina Nieminen, Raimo K. Tuominen & Eeva Moilanen. (2013) Down-Regulation of Protein Kinase Cδ Inhibits Inducible Nitric Oxide Synthase Expression through IRF1. PLoS ONE 8:1, pages e52741.
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Daria Mochly-Rosen, Kanad Das & Kevin V. Grimes. (2012) Protein kinase C, an elusive therapeutic target?. Nature Reviews Drug Discovery 11:12, pages 937-957.
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Angelike Triantafyllou, Alfiya Bikineyeva, Anna Dikalova, Rafal Nazarewicz, Stamatios Lerakis & Sergey Dikalov. (2011) Anti-inflammatory activity of Chios mastic gum is associated with inhibition of TNF-alpha induced oxidative stress. Nutrition Journal 10:1.
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Maurice J. van Eis, Jean-Pierre Evenou, Philipp Floersheim, Christoph Gaul, Sandra W. Cowan-Jacob, Lauren Monovich, Gabriele Rummel, Walter Schuler, Wilhelm Stark, Andre Strauss, Anette von Matt, Eric Vangrevelinghe, Juergen Wagner & Nicolas Soldermann. (2011) 2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes. Bioorganic & Medicinal Chemistry Letters 21:24, pages 7367-7372.
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Yuri Saito, Hirohiko Shibayama, Hirokazu Tanaka, Akira Tanimura & Yuzuru Kanakura. (2011) A cell-death-defying factor, anamorsin mediates cell growth through inactivation of PKC and p38MAPK. Biochemical and Biophysical Research Communications 405:2, pages 303-307.
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Tiina Leppänen, Ulla Jalonen, Riku Korhonen, Raimo K. Tuominen & Eeva Moilanen. (2010) Inhibition of protein kinase Cδ reduces tristetraprolin expression by destabilizing its mRNA in activated macrophages. European Journal of Pharmacology 628:1-3, pages 220-225.
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Peter M. Blumberg, Noemi Kedei, Nancy E. Lewin, Dazhi Yang, Juan Tao, Andrea Telek & Tamas Geczy. 2010. Protein Kinase C in Cancer Signaling and Therapy. Protein Kinase C in Cancer Signaling and Therapy 25 53 .
Tianzhi Zhang, Nicola Y. Edwards, Marco Bonizzoni & Eric V. Anslyn. (2009) The Use of Differential Receptors to Pattern Peptide Phosphorylation. Journal of the American Chemical Society 131:33, pages 11976-11984.
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M. Meier, J. Menne & H. Haller. (2009) Targeting the protein kinase C family in the diabetic kidney: lessons from analysis of mutant mice. Diabetologia 52:5, pages 765-775.
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L Jiang, X F Wei, D H Yi, P Xu, H Liu, Q Chang, S M Yang, Z F Li, H B Gao & G J Hao. (2009) Synergistic effects of cyclic strain and Th1-like cytokines on tenascin-C production by rheumatic aortic valve interstitial cells. Clinical and Experimental Immunology 155:2, pages 216-223.
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