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PAR-4 as a possible new target for pancreatic cancer therapy

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Pages 611-620 | Published online: 28 Apr 2010

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Wu Qinan, Zhang Ling & Chen Bing. (2014) PAR-4: a possible new target for age-related disease. Expert Opinion on Therapeutic Targets 18:8, pages 917-927.
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Rosalyn B Irby & Christina LB Kline. (2013) Par-4 as a potential target for cancer therapy. Expert Opinion on Therapeutic Targets 17:1, pages 77-87.
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Yang Liu, Wei Xu, Mingxue Li, Yueying Yang, Dejuan Sun, Lidian Chen, Hua Li & Lixia Chen. (2023) The regulatory mechanisms and inhibitors of isocitrate dehydrogenase 1 in cancer. Acta Pharmaceutica Sinica B 13:4, pages 1438-1466.
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Anees Rahman Cheratta, Faisal Thayyullathil, Siraj Pallichankandy, Karthikeyan Subburayan, Ameer Alakkal & Sehamuddin Galadari. (2021) Prostate apoptosis response-4 and tumor suppression: it’s not just about apoptosis anymore. Cell Death & Disease 12:1.
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Md. Hafiz Uddin, Asfar S. Azmi & Ramzi M. Mohammad. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4 161 170 .
Mir Mohd Faheem, Reyaz ur Rasool, Syed Mudabir Ahmad, Vijay Lakshmi Jamwal, Souneek Chakraborty, Archana Katoch, Sumit G. Gandhi, Madhulika Bhagat & Anindya Goswami. (2020) Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-β/ Smad4 axis driving the cells towards lethal EMT. European Journal of Cell Biology 99:4, pages 151076.
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Renata Virgínia Cavalcanti Santos, Wanessa Layssa Batista de Sena, Flaviana Alves dos Santos, Antônio Felix da Silva Filho, Marina Galdino da Rocha Pitta, Maira Galdino da Rocha Pitta, Moacyr Barreto de Melo Rego & Michelly Cristiny Pereira. (2019) Potential Therapeutic Agents Against Par-4 Target for Cancer Treatment: Where Are We Going?. Current Drug Targets 20:6, pages 635-654.
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Reyaz Ur Rasool, Debasis Nayak, Souneek Chakraborty, Archana Katoch, Mir Mohd Faheem, Hina Amin & Anindya Goswami. (2016) A journey beyond apoptosis: new enigma of controlling metastasis by pro-apoptotic Par-4. Clinical & Experimental Metastasis 33:8, pages 757-764.
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Kevin Brasseur, François Fabi, Pascal Adam, Sophie Parent, Laurent Lessard & Eric Asselin. (2016) Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells. Oncotarget 7:24, pages 36971-36987.
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T P Das, S Suman, H Alatassi, M K Ankem & C Damodaran. (2016) Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer. Cell Death & Disease 7:2, pages e2111-e2111.
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Yinxing Liu, Misty R. Gilbert, Natasha Kyprianou, Vivek M. Rangnekar & Craig Horbinski. (2014) The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells. Acta Neuropathologica 128:5, pages 723-732.
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Yu-Fen Huang, Hsiang-Yuan Yeh & Von-Wun Soo. (2013) Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation. BMC Medical Genomics 6:S3.
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Tao Wang, Wen-qiao Zang, Min Li, Na Wang, Yu-ling Zheng & Guo-qiang Zhao. (2012) RETRACTED ARTICLE: Effect of miR-451 on the Biological Behavior of the Esophageal Carcinoma Cell Line EC9706. Digestive Diseases and Sciences 58:3, pages 706-714.
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Asfar S. Azmi, Amro Aboukameel, Bin Bao, Fazlul H. Sarkar, Philip A. Philip, Michael Kauffman, Sharon Shacham & Ramzi M. Mohammad. (2013) Selective Inhibitors of Nuclear Export Block Pancreatic Cancer Cell Proliferation and Reduce Tumor Growth in Mice. Gastroenterology 144:2, pages 447-456.
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Si Shi, Wantong Yao, Jin Xu, Jiang Long, Chen Liu & Xianjun Yu. (2012) Combinational therapy: New hope for pancreatic cancer?. Cancer Letters 317:2, pages 127-135.
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Christina Leah B. Kline & Rosalyn B. Irby. (2011) The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU. Apoptosis 16:12, pages 1285-1294.
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Ashiq Masood, Asfar S. Azmi & Ramzi M. Mohammad. (2011) Small Molecule Inhibitors of Bcl-2 Family Proteins for Pancreatic Cancer Therapy. Cancers 3:2, pages 1527-1549.
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