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Expert Opinion on Therapeutic Targets Volume 15, 2011 - Issue 4
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Reviews

Targets of chymase inhibitors

Shinji Takai Osaka Medical College, Department of Pharmacology, Daigaku-machi 2-7, Takatsuki City, Osaka 569-8686, Japan +81 72 684 7292; +81 72 684 6518; [email protected]
, PhD,
Denan Jin Osaka Medical College, Department of Pharmacology, Daigaku-machi 2-7, Takatsuki City, Osaka 569-8686, Japan +81 72 684 7292; +81 72 684 6518; [email protected]
, MD PhD &
Mizuo Miyazaki Osaka Medical College, Department of Pharmacology, Daigaku-machi 2-7, Takatsuki City, Osaka 569-8686, Japan +81 72 684 7292; +81 72 684 6518; [email protected]
, MD PhD
Pages 519-527 | Published online: 04 Feb 2011

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Niren K Shah, Rushab Choksi & Benjamin J Epstein. (2011) Less RAAS is more, or not. Expert Review of Cardiovascular Therapy 9:11, pages 1363-1365.
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Sarfaraz Ahmad & Carlos M. Ferrario. 2023. The Renin Angiotensin System in Cardiovascular Disease. The Renin Angiotensin System in Cardiovascular Disease 159 172 .
Aida Paivandy & Gunnar Pejler. (2021) Novel Strategies to Target Mast Cells in Disease. Journal of Innate Immunity 13:3, pages 131-147.
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Patrícia Rocha Martins, Rodolfo Duarte Nascimento, Aline Tomaz dos Santos, Enio Chaves de Oliveira, Patricia Massara Martinelli & Débora d’Avila Reis. (2018) Mast cell-nerve interaction in the colon of Trypanosoma cruzi-infected individuals with chagasic megacolon. Parasitology Research 117:4, pages 1147-1158.
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Carlos M. Ferrario & Adam E. Mullick. (2017) Renin angiotensin aldosterone inhibition in the treatment of cardiovascular disease. Pharmacological Research 125, pages 57-71.
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Aliasghar Vahidinia, Behnam Heshmatian, Iraj Salehi & Mohammad Zarei. (2015) Garlic Powder Effect on Plasma Renin Activity, and Cardiovascular Effects of Intravenous Angiotensin I and Angiotensin II in Normotensive and Hypertensive Male Rats. Avicenna Journal of Medical Biochemistry 3:2.
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Shinsuke Masubuchi, Shinji Takai, Denan Jin, Keitaro Tashiro, Koji Komeda, Zhong-Lian Li, Yoshinori Otsuki, Haruki Okamura, Michihiro Hayashi & Kazuhisa Uchiyama. (2013) Chymase inhibitor ameliorates hepatic steatosis and fibrosis on established non-alcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet. Hepatology Research 43:9, pages 970-978.
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Martin Houde, Marc-David Jamain, Julie Labonté, Louisane Desbiens, Gunnar Pejler, Michael Gurish, Shinji Takai & Pedro D'Orléans-Juste. (2013) Pivotal Role of Mouse Mast Cell Protease 4 in the Conversion and Pressor Properties of Big-Endothelin-1. Journal of Pharmacology and Experimental Therapeutics 346:1, pages 31-37.
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Steven J. Taylor, Anil K. Padyana, Asitha Abeywardane, Shuang Liang, Ming-Hong Hao, Stéphane De Lombaert, John Proudfoot, Bennett S. FarmerIIIIII, Xiang Li, Brandon Collins, Leslie Martin, Daniel R. Albaugh, Melissa Hill-Drzewi, Steven S. Pullen & Hidenori Takahashi. (2013) Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. Journal of Medicinal Chemistry 56:11, pages 4465-4481.
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George H. Caughey. 2013. Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes 2675 2683 .
Jane Spirkoski, Fabio R. Melo, Mirjana Grujic, Gabriela Calounova, Anders Lundequist, Sara Wernersson & Gunnar Pejler. (2012) Mast cell apoptosis induced by siramesine, a sigma-2 receptor agonist. Biochemical Pharmacology 84:12, pages 1671-1680.
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S Heuston & NP Hyland. (2012) Chymase inhibition as a pharmacological target: a role in inflammatory and functional gastrointestinal disorders?. British Journal of Pharmacology 167:4, pages 732-740.
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Michel BurnierAH Jan DanserAnton JM Roks. 2012. Clinical Applications of Renin–Angiotensin System Inhibitors. Clinical Applications of Renin–Angiotensin System Inhibitors 104 114 .
Theoharis C. Theoharides, Nikolaos Sismanopoulos, Danae-Anastasia Delivanis, Bodi Zhang, Erifili E. Hatziagelaki & Dimitrios Kalogeromitros. (2011) Mast cells squeeze the heart and stretch the gird: Their role in atherosclerosis and obesity. Trends in Pharmacological Sciences 32:9, pages 534-542.
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