613
Views
34
CrossRef citations to date
0
Altmetric
Reviews

Targeting embryonic signaling pathways in cancer therapy

, MD FACP, , MD MSc & , MD
Pages 131-145 | Published online: 12 Jan 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Li-Li-Qiang Ding, Song-Feng Hu, Xing-Wei He, Peng Zhang, Fen-Fen Zhao, Ting-Ping Liu, Qin Zhang, Fan He, Ying Yu, Peng Xiong & Chang-Kang Wang. (2022) Acupuncture combined with moxibustion promote the recovery of spinal cord injury in correlation with Shh/Gli-1 signaling pathway. The Journal of Spinal Cord Medicine 45:1, pages 106-116.
Read now
Amparo Galán & Susana Rodríguez-Navarro. (2012) Sus1/ENY2: a multitasking protein in eukaryotic gene expression. Critical Reviews in Biochemistry and Molecular Biology 47:6, pages 556-568.
Read now

Articles from other publishers (32)

Monika Gulia, Suchitra Nishal, Balaji Maddiboyina, Rohit Dutt, Prasanna Kumar Desu, Rubina Wadhwa & Vikas Jhawat. (2023) Physiological Pathway, diagnosis and nanotechnology based treatment strategies for ovarian Cancer: A review. Medicine in Omics 8, pages 100020.
Crossref
Xinqiang Song, Huanhuan He, Yu Zhang, Jinke Fan & Lei Wang. (2022) Mechanisms of action of triptolide against colorectal cancer: insights from proteomic and phosphoproteomic analyses. Aging 14:7, pages 3084-3104.
Crossref
Rupesh Jain, Sunil Kumar Dubey & Gautam Singhvi. (2022) The Hedgehog pathway and its inhibitors: Emerging therapeutic approaches for basal cell carcinoma. Drug Discovery Today 27:4, pages 1176-1183.
Crossref
Özlem Altundag, Hande Canpinar & Betül Çelebi‐Saltik. (2021) Methionine affects the expression of pluripotency genes and protein levels associated with methionine metabolism in adult, fetal, and cancer stem cells. Journal of Cellular Biochemistry 123:2, pages 406-416.
Crossref
Özlem Altundag & Betül Çelebi-Saltik. (2021) From Embryo to Adult: One Carbon Metabolism in Stem Cells. Current Stem Cell Research & Therapy 16:2, pages 175-188.
Crossref
Sabrina Zema, Maria Pelullo, Francesca Nardozza, Maria Pia Felli, Isabella Screpanti & Diana Bellavia. (2020) A Dynamic Role of Mastermind-Like 1: A Journey Through the Main (Path)ways Between Development and Cancer. Frontiers in Cell and Developmental Biology 8.
Crossref
Yan-Long Kong, Yi-Fei Wang, Zhong-Sheng Zhu, Zheng-Wei Deng, Jing Chen, Dong Zhang, Qun-Hua Jiang, Shi-Chang Zhao & Ya-Dong Zhang. (2019) RETRACTED: Silencing of the MEKK2/MEKK3 Pathway Protects against Spinal Cord Injury via the Hedgehog Pathway and the JNK Pathway. Molecular Therapy - Nucleic Acids 17, pages 578-589.
Crossref
Maria Pelullo, Sabrina Zema, Francesca Nardozza, Saula Checquolo, Isabella Screpanti & Diana Bellavia. (2019) Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer. Frontiers in Genetics 10.
Crossref
Rosamaria Lappano, Yves Jacquot & Marcello Maggiolini. (2018) GPCR Modulation in Breast Cancer. International Journal of Molecular Sciences 19:12, pages 3840.
Crossref
Li Pan, Hongli Yang, Wenqiang Tang, Cong Xu, Shuangfeng Chen, Zhen Meng, Keyi Li & Haiying Chen. (2017) Pathway-focused PCR array profiling of CAL-27 cell with over-expressed ZNF750. Oncotarget 9:1, pages 566-575.
Crossref
Daishi Chen, Manfred Rauh, Michael Buchfelder, Ilker Y. Eyupoglu & Nicolai Savaskan. (2017) The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas. Oncotarget 8:31, pages 51164-51176.
Crossref
Chiaki Tsuge Ishida, Chang Shu, Marc-Eric Halatsch, Mike-Andrew Westhoff, Dario C. Altieri, Georg Karpel-Massler & Markus David Siegelin. (2017) Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma. Oncotarget 8:23, pages 37140-37153.
Crossref
Fujia Wu, Yu Zhang, Bo Sun, Andrew P. McMahon & Yu Wang. (2017) Hedgehog Signaling: From Basic Biology to Cancer Therapy. Cell Chemical Biology 24:3, pages 252-280.
Crossref
Sheng-Fan Wang, Meng-Shian Chen, Yueh-Ching Chou, Yune-Fang Ueng, Pen-Hui Yin, Tien-Shun Yeh & Hsin-Chen Lee. (2016) Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway. Oncotarget 7:45, pages 74132-74151.
Crossref
Xiaowei Zhang, Ruixi Hua, Xiaofeng Wang, Mingzhu Huang, Lu Gan, Zhenhua Wu, Jiejun Zhang, Hongqiang Wang, Yufan Cheng, Jin Li & Weijian Guo. (2016) Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer. Oncotarget 7:9, pages 9815-9831.
Crossref
Massimo Alfano, Filippo Canducci, Manuela Nebuloni, Massimo Clementi, Francesco Montorsi & Andrea Salonia. (2015) The interplay of extracellular matrix and microbiome in urothelial bladder cancer. Nature Reviews Urology 13:2, pages 77-90.
Crossref
Francesca Pistollato, Susanne Bremer-Hoffmann, Giuseppe Basso, Sandra Sumalla Cano, Iñaki Elio, Manuel Masias Vergara, Francesca Giampieri & Maurizio Battino. (2015) Targeting Glioblastoma with the Use of Phytocompounds and Nanoparticles. Targeted Oncology 11:1, pages 1-16.
Crossref
Francesca Pistollato, Francesca Giampieri & Maurizio Battino. (2015) The use of plant-derived bioactive compounds to target cancer stem cells and modulate tumor microenvironment. Food and Chemical Toxicology 75, pages 58-70.
Crossref
Alan K.S. Chiang, N.K. Mak & Wai Tong Ng. (2014) Translational research in nasopharyngeal carcinoma. Oral Oncology 50:5, pages 345-352.
Crossref
Naoko Takebe, Pamela Jo Harris, Yutaka Kondo, Abhilasha Nair, S. Percy Ivy & Hideyuki Saya. 2014. Cancer Stem Cells. Cancer Stem Cells 295 317 .
Andrei Turtoi, Arnaud Blomme, Delphine Debois, Joan Somja, David Delvaux, Georgios Patsos, Emmanuel Di Valentin, Olivier Peulen, Eugène Nzaramba Mutijima, Edwin De Pauw, Philippe Delvenne, Olivier Detry & Vincent Castronovo. (2014) Organized proteomic heterogeneity in colorectal cancer liver metastases and implications for therapies. Hepatology 59:3, pages 924-934.
Crossref
Galina I. Botchkina. 2017. Encyclopedia of Cancer. Encyclopedia of Cancer 763 767 .
Galina I. Botchkina. 2014. Encyclopedia of Cancer. Encyclopedia of Cancer 1 5 .
Daniela Perotti, Peter Hohenstein, Italia Bongarzone, Mariana Maschietto, Mark Weeks, Paolo Radice & Kathy Pritchard-Jones. (2013) Is Wilms Tumor a Candidate Neoplasia for Treatment with WNT/β-Catenin Pathway Modulators?—A Report from the Renal Tumors Biology-Driven Drug Development Workshop. Molecular Cancer Therapeutics 12:12, pages 2619-2627.
Crossref
Rebecca C. Arend, Angelina I. Londoño-Joshi, J. Michael StraughnJr.Jr. & Donald J. Buchsbaum. (2013) The Wnt/β-catenin pathway in ovarian cancer: A review. Gynecologic Oncology 131:3, pages 772-779.
Crossref
Galina Botchkina. (2013) Colon cancer stem cells – From basic to clinical application. Cancer Letters 338:1, pages 127-140.
Crossref
Iacopo Petrini, Yisong Wang, Paolo A. Zucali, Hye Seung Lee, Trung Pham, Donna Voeller, Paul S. Meltzer & Giuseppe Giaccone. (2013) Copy Number Aberrations of Genes Regulating Normal Thymus Development in Thymic Epithelial Tumors. Clinical Cancer Research 19:8, pages 1960-1971.
Crossref
Juan L. Iovanna, David L. Marks, Martin E. Fernandez-Zapico & Raul Urrutia. (2013) Mechanistic Insights into Self-Reinforcing Processes Driving Abnormal Histogenesis During the Development of Pancreatic Cancer. The American Journal of Pathology 182:4, pages 1078-1086.
Crossref
Lilian E. van Vlerken, Elaine M. Hurt & Robert E. Hollingsworth. (2012) The role of epigenetic regulation in stem cell and cancer biology. Journal of Molecular Medicine 90:7, pages 791-801.
Crossref
Christian Tendeng. (2012) Experiments, measurements, and mathematical modeling to decipher time signals in development. Birth Defects Research Part C: Embryo Today: Reviews 96:2, pages 121-131.
Crossref
Anna Mae Diehl. (2012) Neighborhood watch orchestrates liver regeneration. Nature Medicine 18:4, pages 497-499.
Crossref
Appalaraju Jaggupilli & Eyad Elkord. (2012) Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity. Clinical and Developmental Immunology 2012, pages 1-11.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.