2,600
Views
26
CrossRef citations to date
0
Altmetric
Editorial

Targeting IL-8 signalling to inhibit breast cancer stem cell activity

, , &
Pages 1235-1241 | Published online: 14 Sep 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Hajar Rajayi, Parsova Tavasolian, Alaleh Rezalotfi & Marzieh Ebrahimi. (2019) Cancer Stem Cells Targeting; the Lessons from the Interaction of the Immune System, the Cancer Stem Cells and the Tumor Niche. International Reviews of Immunology 38:6, pages 267-283.
Read now
Fang Jin, Yajing Miao, Pengyu Xu & Xiaofei Qiu. (2018) IL-8 regulates the stemness properties of cancer stem cells in the small-cell lung cancer cell line H446. OncoTargets and Therapy 11, pages 5723-5731.
Read now

Articles from other publishers (24)

Mia C. Borlongan & Hongbin Wang. (2023) Profiling and targeting cancer stem cell signaling pathways for cancer therapeutics. Frontiers in Cell and Developmental Biology 11.
Crossref
Guanglin Cui, Ziqi Wang, Hanzhe Liu & Zhigang Pang. (2022) Cytokine-mediated crosstalk between cancer stem cells and their inflammatory niche from the colorectal precancerous adenoma stage to the cancerous stage: Mechanisms and clinical implications. Frontiers in Immunology 13.
Crossref
Maria Francesca Santolla, Marianna Talia, Francesca Cirillo, Domenica Scordamaglia, Salvatore De Rosis, Asia Spinelli, Anna Maria Miglietta, Bruno Nardo, Gianfranco Filippelli, Ernestina Marianna De Francesco, Antonino Belfiore, Rosamaria Lappano & Marcello Maggiolini. (2022) The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells. Cells 11:15, pages 2402.
Crossref
Guanglin Cui, Gui Li, Zhigang Pang, Jon Florholmen & Rasmus Goll. (2022) The presentation and regulation of the IL-8 network in the epithelial cancer stem-like cell niche in patients with colorectal cancer. Biomedicine & Pharmacotherapy 152, pages 113252.
Crossref
Shahang Luo, Guanghui Yang, Peng Ye, Nengqi Cao, Xiaoxia Chi, Wen-Hao Yang & Xiuwen Yan. (2022) Macrophages Are a Double-Edged Sword: Molecular Crosstalk between Tumor-Associated Macrophages and Cancer Stem Cells. Biomolecules 12:6, pages 850.
Crossref
Amaresh Mishra, Kamrul Hassan Suman, Nisha Nair, Jaseela Majeed & Vishwas Tripathi. (2021) An updated review on the role of the CXCL8-CXCR1/2 axis in the progression and metastasis of breast cancer. Molecular Biology Reports 48:9, pages 6551-6561.
Crossref
Neng Wang, Shengqi Wang, Xuan Wang, Yifeng Zheng, Bowen Yang, Juping Zhang, Bo Pan, Jianli Gao & Zhiyu Wang. (2021) Research trends in pharmacological modulation of tumor‐associated macrophages. Clinical and Translational Medicine 11:1.
Crossref
Aliyu Muhammad, Babangida Sanusi Katsayal, Gilead Ebiegberi Forcados, Ibrahim Malami, Ibrahim Babangida Abubakar, Amina Isah kandi, Adam Muntaka Idris, Sabi’u Yusuf, Salihu Muktar Musa, Nagedu Monday & Zak-wan Sidi Umar. (2020) In silico predictions on the possible mechanism of action of selected bioactive compounds against breast cancer. In Silico Pharmacology 8:1.
Crossref
Wei Tang, Zunyan Li, Xian Li & Zhonghua Huo. (2020) High CXCR2 expression predicts poor prognosis in adult patients with acute myeloid leukemia. Therapeutic Advances in Hematology 11, pages 204062072095858.
Crossref
Nehal I. Ghoneim, Rania Hassan Mohamed, Alaa Gamal, Shireen Magdy & Nagwa El-Badri. 2020. Regenerative Medicine and Stem Cell Biology. Regenerative Medicine and Stem Cell Biology 151 192 .
Deniz Cansen Kahraman, Tamer Kahraman & Rengul Cetin-Atalay. (2019) Targeting PI3K/Akt/mTOR Pathway Identifies Differential Expression and Functional Role of IL8 in Liver Cancer Stem Cell Enrichment. Molecular Cancer Therapeutics 18:11, pages 2146-2157.
Crossref
Qianyu Guo, Fan Huang, Christophe Goncalves, Sonia V. del Rincón & Wilson H. MillerJrJr. 2019. Immunotherapy of Cancer. Immunotherapy of Cancer 1 62 .
Weilong Chen, Yuanyuan Qin & Suling Liu. (2018) Cytokines, breast cancer stem cells (BCSCs) and chemoresistance. Clinical and Translational Medicine 7:1.
Crossref
Masayoshi Hosono, Yu-Ichiro Koma, Nobuhisa Takase, Naoki Urakawa, Nobuhide Higashino, Kazuki Suemune, Himiko Kodaira, Mari Nishio, Manabu Shigeoka, Yoshihiro Kakeji & Hiroshi Yokozaki. (2017) CXCL8 derived from tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression by promoting migration and invasion of cancer cells. Oncotarget 8:62, pages 106071-106088.
Crossref
Chun-Ho Shih, Tin-Bin Chiang & Wen-Jeng Wang. (2017) Synergistic suppression of a disintegrin acurhagin-C in combination with AZD4547 and reparixin on terminating development for human osteosarcoma MG-63 cell. Biochemical and Biophysical Research Communications 492:3, pages 513-519.
Crossref
Federica Liotti, Maria De Pizzol, Marcello Allegretti, Nella Prevete & Rosa Marina Melillo. (2017) Multiple anti-tumor effects of Reparixin on thyroid cancer. Oncotarget 8:22, pages 35946-35961.
Crossref
Nancy Adriana Espinoza-Sánchez, Gloria Karina Chimal-Ramírez, Alejandra Mantilla & Ezequiel Moisés Fuentes-Pananá. (2017) IL-1β, IL-8, and Matrix Metalloproteinases-1, -2, and -10 Are Enriched upon Monocyte–Breast Cancer Cell Cocultivation in a Matrigel-Based Three-Dimensional System. Frontiers in Immunology 8.
Crossref
Waleed O. Twal, Amy E. Wahlquist & Sundaravadivel Balasubramanian. (2016) Yogic breathing when compared to attention control reduces the levels of pro-inflammatory biomarkers in saliva: a pilot randomized controlled trial. BMC Complementary and Alternative Medicine 16:1.
Crossref
Qian Liu, Anping Li, Yijun Tian, Jennifer D. Wu, Yu Liu, Tengfei Li, Yuan Chen, Xinwei Han & Kongming Wu. (2016) The CXCL8-CXCR1/2 pathways in cancer. Cytokine & Growth Factor Reviews 31, pages 61-71.
Crossref
Jung-Min Lee, Jane B. Trepel, Peter Choyke, Liang Cao, Tristan Sissung, Nicole Houston, Minshu Yu, William D. Figg, Ismail Baris Turkbey, Seth M. Steinberg, Min-Jung Lee, S. Percy Ivy, Joyce F. Liu, Ursula A. Matulonis & Elise C. Kohn. (2015) CECs and IL-8 Have Prognostic and Predictive Utility in Patients with Recurrent Platinum-Sensitive Ovarian Cancer: Biomarker Correlates from the Randomized Phase-2 Trial of Olaparib and Cediranib Compared with Olaparib in Recurrent Platinum-Sensitive Ovarian Cancer. Frontiers in Oncology 5.
Crossref
Nizam Uddin, Rae‐Kwon Kim, Ki‐Chun Yoo, Young‐Heon Kim, Yan‐Hong Cui, In‐Gyu Kim, Yongjoon Suh & Su‐Jae Lee. (2015) Persistent activation of STAT 3 by PIM 2‐driven positive feedback loop for epithelial‐mesenchymal transition in breast cancer . Cancer Science 106:6, pages 718-725.
Crossref
Roberto Solari, James E. Pease & Malcolm Begg. (2015) “Chemokine receptors as therapeutic targets: Why aren’t there more drugs?”. European Journal of Pharmacology 746, pages 363-367.
Crossref
Phuc Van PhamPhuc Van Pham. 2015. Breast Cancer Stem Cells & Therapy Resistance. Breast Cancer Stem Cells & Therapy Resistance 75 96 .
Juan Manuel Iglesias, Olatz Leis, Estíbaliz Pérez Ruiz, Juan Gumuzio Barrie, Francisco Garcia-Garcia, Ariane Aduriz, Izaskun Beloqui, Susana Hernandez-Garcia, Maria Paz Lopez-Mato, Joaquin Dopazo, Atanasio Pandiella, Javier A. Menendez & Angel Garcia Martin. (2014) The Activation of the Sox2 RR2 Pluripotency Transcriptional Reporter in Human Breast Cancer Cell Lines is Dynamic and Labels Cells with Higher Tumorigenic Potential. Frontiers in Oncology 4.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.