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The role of transcription factors in prostate cancer and potential for future RNA interference therapy

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Haleema Azam, Lisa Pierro, Martina Reina, William M Gallagher & Maria Prencipe. (2022) Emerging role for the Serum Response Factor (SRF) as a potential therapeutic target in cancer. Expert Opinion on Therapeutic Targets 26:2, pages 155-169.
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Articles from other publishers (31)

George Doumat, Elia Abou Chawareb, Towfik N. Sebai, Mohammad Hout, Ali Merhe & Yumna Omarzai. 2024. Therapy Resistance in Prostate Cancer. Therapy Resistance in Prostate Cancer 85 106 .
Mingen Lin, Xue Sun & Lei Lv. (2023) New insights and options into the mechanisms and effects of combined targeted therapy and immunotherapy in prostate cancer. Molecular Therapy - Oncolytics 29, pages 91-106.
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Claire Stevens, Alexandria Hightower, Sarah G. Buxbaum, Sara M. Falzarano & Suhn K. Rhie. (2023) Genomic, epigenomic, and transcriptomic signatures of prostate cancer between African American and European American patients. Frontiers in Oncology 13.
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Csilla Sipeky, Teuvo L. J. Tammela, Anssi Auvinen & Johanna Schleutker. (2021) Novel prostate cancer susceptibility gene SP6 predisposes patients to aggressive disease. Prostate Cancer and Prostatic Diseases 24:4, pages 1158-1166.
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Jianwei Lin, Zichao Cao, Dingye Yu & Wei Cai. (2021) Identification of Transcription Factor-Related Gene Signature and Risk Score Model for Colon Adenocarcinoma. Frontiers in Genetics 12.
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Lara S. Costard, Ryan R. Hosn, Harumi Ramanayake, Fergal J. O'Brien & Caroline M. Curtin. (2021) Influences of the 3D microenvironment on cancer cell behaviour and treatment responsiveness: A recent update on lung, breast and prostate cancer models. Acta Biomaterialia 132, pages 360-378.
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Mario Cangiano, Magda Grudniewska, Mark J. Salji, Matti Nykter, Guido Jenster, Alfonso Urbanucci, Zoraide Granchi, Bart Janssen, Graham Hamilton, Hing Y. Leung & Inès J. Beumer. (2021) Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer. Cancers 13:9, pages 2094.
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Hui Xu, Lei Liu, Weilin Li, Duowu Zou, Jun Yu, Lifu Wang & Chi Chun Wong. (2020) Transcription factors in colorectal cancer: molecular mechanism and therapeutic implications. Oncogene 40:9, pages 1555-1569.
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Zhongyu Wang, Jun Shang, Zhiqin Li, Huanhuan Li, Chufan Zhang, Kai He, Shikang Li & Wen Ju. (2020) PIK3CA Is Regulated by CUX1, Promotes Cell Growth and Metastasis in Bladder Cancer via Activating Epithelial-Mesenchymal Transition. Frontiers in Oncology 10.
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Bárbara Matos, John Howl, Carmen Jerónimo & Margarida Fardilha. (2020) The disruption of protein-protein interactions as a therapeutic strategy for prostate cancer. Pharmacological Research 161, pages 105145.
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Juliana Felgueiras, Joana Vieira Silva, Alexandra Nunes, Inês Fernandes, António Patrício, Nuno Maia, Steven Pelech & Margarida Fardilha. (2020) Investigation of spectroscopic and proteomic alterations underlying prostate carcinogenesis. Journal of Proteomics 226, pages 103888.
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Lara S. Costard, Harumi Ramanayake & Caroline M. Curtin. 2020. Biomaterials for 3D Tumor Modeling. Biomaterials for 3D Tumor Modeling 505 532 .
Kwame Osei-Sarfo & Lorraine J. Gudas. (2019) Retinoids induce antagonism between FOXO3A and FOXM1 transcription factors in human oral squamous cell carcinoma (OSCC) cells. PLOS ONE 14:4, pages e0215234.
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Xue Luan, Kamil Rahme, Zhongcheng Cong, Limei Wang, Yifang Zou, Yan He, Hao Yang, Justin D. Holmes, Caitriona M. O'Driscoll & Jianfeng Guo. (2019) Anisamide-targeted PEGylated gold nanoparticles designed to target prostate cancer mediate: Enhanced systemic exposure of siRNA, tumour growth suppression and a synergistic therapeutic response in combination with paclitaxel in mice. European Journal of Pharmaceutics and Biopharmaceutics 137, pages 56-67.
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Kamil Rahme, Jianfeng Guo & Justin D. Holmes. 2019. RNA Interference and Cancer Therapy. RNA Interference and Cancer Therapy 291 301 .
William H. Chappell, Saverio Candido, Stephen L. Abrams, Suzanne Russo, Roger Ove, Alberto M. Martelli, Lucio Cocco, Giulia Ramazzotti, Melchiorre Cervello, Giuseppe Montalto, Linda S. Steelman, Xiaohong Leng, Ralph B. Arlinghaus, Massimo Libra & James A. McCubrey. (2018) Roles of p53, NF-κB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines. Advances in Biological Regulation 69, pages 43-62.
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Damien A. Leach, Vasilios Panagopoulos, Claire Nash, Charlotte Bevan, Axel A. Thomson, Luke A. Selth & Grant Buchanan. (2017) Cell-lineage specificity and role of AP-1 in the prostate fibroblast androgen receptor cistrome. Molecular and Cellular Endocrinology 439, pages 261-272.
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James C. Evans, Meenakshi Malhotra, Jianfeng Guo, Joseph P. O'Shea, Karen Hanrahan, Amanda O'Neill, William D. Landry, Brendan T. Griffin, Raphael Darcy, R. William Watson & Caitriona M. O'Driscoll. (2016) Folate-targeted amphiphilic cyclodextrin.siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and prolonged circulation in vivo. Nanomedicine: Nanotechnology, Biology and Medicine 12:8, pages 2341-2351.
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Kathleen A. Fitzgerald, Jianfeng Guo, Rosanne M. Raftery, Irene Menc?a Casta?o, Caroline M. Curtin, Matt Gooding, Raphael Darcy, Fergal J. O? Brien & Caitriona M. O? Driscoll. (2016) Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis. International Journal of Pharmaceutics 511:2, pages 1058-1069.
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Ana Cecilia Millena, BaoHan T. Vo & Shafiq A. Khan. (2016) JunD Is Required for Proliferation of Prostate Cancer Cells and Plays a Role in Transforming Growth Factor-β (TGF-β)-induced Inhibition of Cell Proliferation. Journal of Biological Chemistry 291:34, pages 17964-17976.
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Jianfeng Guo, Caitriona M. O’Driscoll, Justin D. Holmes & Kamil Rahme. (2016) Bioconjugated gold nanoparticles enhance cellular uptake: A proof of concept study for siRNA delivery in prostate cancer cells. International Journal of Pharmaceutics 509:1-2, pages 16-27.
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Rosanne M. Raftery, David P. Walsh, Irene Mencía Castaño, Andreas Heise, Garry P. Duffy, Sally-Ann Cryan & Fergal J. O'Brien. (2016) Delivering Nucleic-Acid Based Nanomedicines on Biomaterial Scaffolds for Orthopedic Tissue Repair: Challenges, Progress and Future Perspectives. Advanced Materials 28:27, pages 5447-5469.
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Kenneth V. Honn, Yande Guo, Yinlong Cai, Menq‐Jer Lee, Gregory Dyson, Wenliang Zhang & Stephanie C. Tucker. (2016) 12‐HETER1/GPR31, a high‐affinity 12( S )‐hydroxyeicosatetraenoic acid receptor, is significantly up‐regulated in prostate cancer and plays a critical role in prostate cancer progression . The FASEB Journal 30:6, pages 2360-2369.
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Kathleen A. Fitzgerald, Meenakshi Malhotra, Matt Gooding, Florence Sallas, James C. Evans, Raphael Darcy & Caitriona M. O’Driscoll. (2016) A novel, anisamide-targeted cyclodextrin nanoformulation for siRNA delivery to prostate cancer cells expressing the sigma-1 receptor. International Journal of Pharmaceutics 499:1-2, pages 131-145.
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Kathleen A. Fitzgerald, Kamil Rahme, Jianfeng Guo, Justin D. Holmes & Caitriona M. O'Driscoll. (2016) Anisamide-targeted gold nanoparticles for siRNA delivery in prostate cancer – synthesis, physicochemical characterisation and in vitro evaluation. Journal of Materials Chemistry B 4:13, pages 2242-2252.
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Kamil Rahme, Jianfeng Guo, Justin D. Holmes & Caitriona M. O’Driscoll. (2015) Evaluation of the physicochemical properties and the biocompatibility of polyethylene glycol-conjugated gold nanoparticles: A formulation strategy for siRNA delivery. Colloids and Surfaces B: Biointerfaces 135, pages 604-612.
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ZHIJUN WANG, YI GAO, YUSHAN LIU, JIE CHEN, JUNKAI WANG, SISHUN GAN, DANFENG XU & XINGANG CUI. (2015) Tectonic-1 contributes to the growth and migration of prostate cancer cells in vitro. International Journal of Molecular Medicine 36:4, pages 931-938.
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J C Evans, J McCarthy, C Torres-Fuentes, J F Cryan, J Ogier, R Darcy, R W Watson & C M O’Driscoll. (2015) Cyclodextrin mediated delivery of NF-κB and SRF siRNA reduces the invasion potential of prostate cancer cells in vitro. Gene Therapy 22:10, pages 802-810.
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Kathleen A. Fitzgerald, Jianfeng Guo, Erica G. Tierney, Caroline M. Curtin, Meenakshi Malhotra, Raphael Darcy, Fergal J. O'Brien & Caitriona M. O'Driscoll. (2015) The use of collagen-based scaffolds to simulate prostate cancer bone metastases with potential for evaluating delivery of nanoparticulate gene therapeutics. Biomaterials 66, pages 53-66.
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Jianfeng Guo, Kamil Rahme, Kathleen A. Fitzgerald, Justin D. Holmes & Caitriona M. O’Driscoll. (2015) Biomimetic gold nanocomplexes for gene knockdown: Will gold deliver dividends for small interfering RNA nanomedicines?. Nano Research 8:10, pages 3111-3140.
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Carolina Vizcaíno, Sylvia Mansilla & José Portugal. (2015) Sp1 transcription factor: A long-standing target in cancer chemotherapy. Pharmacology & Therapeutics 152, pages 111-124.
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