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Expert Opinion on Therapeutic Targets Volume 19, 2015 - Issue 1
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Review

Therapeutic strategies in extrinsic atopic dermatitis: focus on inhibition of IL-4 as a new pharmacological approach

Vito Di LerniaArcispedale Santa Maria Nuova-IRCCS, Dermatology Unit, viale Risorgimento 68, 42123 Reggio Emilia, Italy
, MD
Pages 87-96 | Published online: 04 Oct 2014

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A Tsianakas & TA Luger. (2015) The anti-IL-4 receptor alpha antibody dupilumab: facing a new era in treating atopic dermatitis. Expert Opinion on Biological Therapy 15:11, pages 1657-1660.
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Articles from other publishers (10)

Jung-Eun Lee, Young-Whan Choi & Dong-Soon Im. (2022) Inhibitory effect of α-cubebenoate on atopic dermatitis-like symptoms by regulating Th2/Th1/Th17 balance in vivo. Journal of Ethnopharmacology 291, pages 115162.
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Guillaume Mestrallet, Nathalie Rouas-Freiss, Joel LeMaoult, Nicolas O. Fortunel & Michele T. Martin. (2021) Skin Immunity and Tolerance: Focus on Epidermal Keratinocytes Expressing HLA-G. Frontiers in Immunology 12.
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Qian Xue, Xia Li, Yuchen Li, Jun Xu, Zhe Wu & Jingtong Wang. (2020) Dialogue between gastrointestinal tract and skin: New insights into the Helicobacter pylori and atopic dermatitis . Helicobacter 26:2.
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Yujiao Meng, Zhengrong Liu, Chunyan Zhai, Tingting Di, Lu Zhang, Lei Zhang, Xinran Xie, Yan Lin, Ning Wang, Jingxia Zhao, Yan Wang & Ping Li. (2019) Paeonol inhibits the development of 1‑chloro‑2,4‑dinitrobenzene‑induced atopic dermatitis via mast and T cells in BALB/c mice. Molecular Medicine Reports.
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Ge Peng, Zhenzhen Mu, Lixia Cui, Pengyue Liu, Ying Wang, Wenqing Wu & Xiuping Han. (2017) Anti-IL-33 Antibody Has a Therapeutic Effect in an Atopic Dermatitis Murine Model Induced by 2, 4-Dinitrochlorobenzene. Inflammation 41:1, pages 154-163.
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Lei Bao, Girish C Mohan, Jaime B Alexander, Caroline Doo, Kui Shen, Jeremy Bao & Lawrence S Chan. (2017) A molecular mechanism for IL-4 suppression of loricrin transcription in epidermal keratinocytes: implication for atopic dermatitis pathogenesis. Innate Immunity 23:8, pages 641-647.
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Mi-Sung Park, Nho-Eul Song, Sang-Ho Baik, Hyun-Ock Pae & Seong Hoon Park. (2017) Oral administration of lactobacilli isolated from Jeotgal, a salted fermented seafood, inhibits the development of 2,4-dinitrofluorobenzene-induced atopic dermatitis in mice. Experimental and Therapeutic Medicine 14:1, pages 635-641.
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Line Fisker Zachariassen, Lukasz Krych, Kåre Engkilde, Dennis Sandris Nielsen, Witold Kot, Camilla Hartmann Friis Hansen & Axel Kornerup Hansen. (2017) Sensitivity to oxazolone induced dermatitis is transferable with gut microbiota in mice. Scientific Reports 7:1.
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Lei Bao, Huayi Zhang, Girish C. Mohan, Kui Shen & Lawrence S. Chan. (2016) Differential expression of inflammation-related genes in IL-4 transgenic mice before and after the onset of atopic dermatitis skin lesions. Molecular and Cellular Probes 30:1, pages 30-38.
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Andrea Montes-Torres, Mar Llamas-Velasco, Alejandra Pérez-Plaza, Guillermo Solano-López & Javier Sánchez-Pérez. (2015) Biological Treatments in Atopic Dermatitis. Journal of Clinical Medicine 4:4, pages 593-613.
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