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Sigma-1 receptor chaperones in neurodegenerative and psychiatric disorders

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Pages 1461-1476 | Published online: 21 Oct 2014

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Mallory Burns, Nicholas Guadagnoli & Christopher R. McCurdy. (2023) Advances with the discovery and development of novel sigma 1 receptor antagonists for the management of pain. Expert Opinion on Drug Discovery 18:7, pages 693-705.
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Mellar P Davis. (2015) Sigma-1 receptors and animal studies centered on pain and analgesia. Expert Opinion on Drug Discovery 10:8, pages 885-900.
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José Miguel Vela, Manuel Merlos & Carmen Almansa. (2015) Investigational sigma-1 receptor antagonists for the treatment of pain. Expert Opinion on Investigational Drugs 24:7, pages 883-896.
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Articles from other publishers (20)

L. Milenina, Z. Krutetskaya, V. Antonov, N. Krutetskaya, V. Badulina & A. Simonyan. (2022) NEUROLEPTICS ATTENUATE Ca2+ RESPONSES INDUCED BY GLUTOXIM AND MOLIXAN IN MACROPHAGES. Russian Journal of Biological Physics and Chemisrty 7:1, pages 127-136.
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Bénédicte Oxombre, Fahima Madouri, Anne-Sophie Journé, Séverine Ravez, Eloise Woitrain, Pascal Odou, Nathalie Duhal, Sandro Ninni, David Montaigne, Nadira Delhem, Patrick Vermersch & Patricia Melnyk. (2022) Safe and Efficient Sigma1 Ligand: A Potential Drug Candidate for Multiple Sclerosis. International Journal of Molecular Sciences 23:19, pages 11893.
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Ahmed S. Gouda & Bruno Mégarbane. (2022) Molecular Bases of Serotonin Reuptake Inhibitor Antidepressant-Attributed Effects in COVID-19: A New Insight on the Role of Bradykinins. Journal of Personalized Medicine 12:9, pages 1487.
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L. S. Milenina, Z. I. Krutetskaya, V. G. Antonov & N. I. Krutetskaya. (2022) Sigma-1 Receptor Ligands Chlorpromazine and Trifluoperazine Attenuate Ca2+ Responses in Rat Peritoneal Macrophages. Cell and Tissue Biology 16:3, pages 233-244.
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Te Jiang, Di Zhao, Zhiyuan Zheng & Zhankui Li. (2022) Sigma-1 Receptor Alleviates Airway Inflammation and Airway Remodeling Through AMPK/CXCR4 Signal Pathway. Inflammation 45:3, pages 1298-1312.
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Simon Couly, Nino Goguadze, Yuko Yasui, Yuriko Kimura, Shao-Ming Wang, Nino Sharikadze, Hsiang-En Wu & Tsung-Ping Su. (2020) Knocking Out Sigma-1 Receptors Reveals Diverse Health Problems. Cellular and Molecular Neurobiology 42:3, pages 597-620.
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Adonis Sfera, Carolina Osorio, Jose E. Campo Maldonado, Afzaal Jafri, Aaron D. Chokka, Carlos Manuel Zapata Martín del Campo & Zisis Kozlakidis. 2022. Biotechnology to Combat COVID-19. Biotechnology to Combat COVID-19.
Ning-hua Wu, Yu Ye, Bin-bin Wan, Yuan-dong Yu, Chao Liu & Qing-jie Chen. (2021) Emerging Benefits: Pathophysiological Functions and Target Drugs of the Sigma-1 Receptor in Neurodegenerative Diseases. Molecular Neurobiology 58:11, pages 5649-5666.
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Heather Wilson, Marios Politis, Eugenii A. Rabiner & Lefkos T. Middleton. (2020) Novel PET Biomarkers to Disentangle Molecular Pathways across Age-Related Neurodegenerative Diseases. Cells 9:12, pages 2581.
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Nikoletta Almási, Szilvia Török, Szabolcs Dvorácskó, Csaba Tömböly, Ákos Csonka, Zoltán Baráth, Zsolt Murlasits, Zsuzsanna Valkusz, Anikó Pósa, Csaba Varga & Krisztina Kupai. (2020) Lessons on the Sigma-1 Receptor in TNBS-Induced Rat Colitis: Modulation of the UCHL-1, IL-6 Pathway. International Journal of Molecular Sciences 21:11, pages 4046.
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Hongmei Jia, Zhengxin Cai, Daniel Holden, Yingfang He, Shu-fei Lin, Songye Li, Evan Baum, Anupama Shirali, Michael Kapinos, Hong Gao, Jim Ropchan & Yiyun Huang. (2020) Positron Emission Tomography Imaging Evaluation of a Novel 18 F-Labeled Sigma-1 Receptor Radioligand in Cynomolgus Monkeys . ACS Chemical Neuroscience 11:11, pages 1673-1681.
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Fabio Bello, Mario Giannella, Gianfabio Giorgioni, Alessandro Piergentili & Wilma Quaglia. (2019) Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson’s Disease. Biomolecules 9:4, pages 142.
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Talya Shacham, Neeraj Sharma & Gerardo Z. Lederkremer. (2019) Protein Misfolding and ER Stress in Huntington's Disease. Frontiers in Molecular Biosciences 6.
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Tzu-Yu Weng, Denise T. Hung, Tsung-Ping Su & Shang-Yi A. Tsai. (2017) Loss of Sigma-1 Receptor Chaperone Promotes Astrocytosis and Enhances the Nrf2 Antioxidant Defense. Oxidative Medicine and Cellular Longevity 2017, pages 1-14.
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Yu Cai, Lu Yang, Fang Niu, Ke Liao & Shilpa Buch. 2017. Sigma Receptors: Their Role in Disease and as Therapeutic Targets. Sigma Receptors: Their Role in Disease and as Therapeutic Targets 163 175 .
Felix J. Kim & Christina M. Maher. 2017. Sigma Proteins: Evolution of the Concept of Sigma Receptors. Sigma Proteins: Evolution of the Concept of Sigma Receptors 237 308 .
Xudong Cao, Yin Chen, Yifang Zhang, Yu Lan, Juecheng Zhang, Xiangqing Xu, Yinli Qiu, Song Zhao, Xin Liu, Bi-Feng Liu & Guisen Zhang. (2016) Synthesis and Biological Evaluation of Novel σ 1 Receptor Ligands for Treating Neuropathic Pain: 6-Hydroxypyridazinones . Journal of Medicinal Chemistry 59:7, pages 2942-2961.
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Shyam Srivats, Dilshan Balasuriya, Mathias Pasche, Gerard Vistal, J. Michael Edwardson, Colin W. Taylor & Ruth D. Murrell-Lagnado. (2016) Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1. Journal of Cell Biology 213:1, pages 65-79.
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Ede Frecska, Petra Bokor & Michael Winkelman. (2016) The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization. Frontiers in Pharmacology 7.
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Yuko Yasui & Tsung-Ping Su. (2016) Potential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and Methamphetamine. Journal of Drug and Alcohol Research 5, pages 1-15.
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