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Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis

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JungIn Um, Ji-Hyung Lee, Da-Woon Jung & Darren R. Williams. (2018) Re-education begins at home: an overview of the discovery of in vivo-active small molecule modulators of endogenous stem cells. Expert Opinion on Drug Discovery 13:4, pages 307-326.
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Holger Schmid & Wolfgang Jelkmann. (2016) Investigational therapies for renal disease-induced anemia. Expert Opinion on Investigational Drugs 25:8, pages 901-916.
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Articles from other publishers (25)

Huixin Chen, Jing Yu, Qing Wei, Yu Zhang, Xilin Ouyang & Shun Wang. (2023) Intravenous iron and erythropoietin therapy for postoperative anemia among orthopedic surgery patients. Journal of Orthopaedic Surgery and Research 18:1.
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Yuliana Heri Suselo, Dono Indarto, Brian Wasita & Hartono Hartono. (2023) Alkaloid fraction of Mirabilis jalapa Linn. flowers has low cytotoxicity and increases iron absorption through Erythropoietin-Matriptase-2-Hepcidin pathway in iron deficiency Hepatocarcinoma cell model. Saudi Journal of Biological Sciences 30:1, pages 103508.
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S. V. Semochkin. (2022) Practical aspects of the use of erythropoiesis-stimulating agent in patients with hematological malignancy. Meditsinskiy sovet = Medical Council.
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Xinyao Yi, Wenhui Yan, Tingli Guo, Na Liu, Zhuanzhuan Wang, Jia Shang, Xiaotong Wei, Xin Cui, Yuzhuo Sun, Shuting Ren & Lina Chen. (2022) Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy. Frontiers in Pharmacology 13.
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Almut S Eisele, Jason Cosgrove, Aurelie Magniez, Emilie Tubeuf, Sabrina Tenreira Bento, Cecile Conrad, Fanny Cayrac, Tamar Tak, Anne-Marie Lyne, Jos Urbanus & Leïla Perié. (2022) Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells. eLife 11.
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Sara Ottolenghi, Giuseppina Milano, Michele Dei Cas, Tina O. Findley, Rita Paroni & Antonio F. Corno. (2021) Can Erythropoietin Reduce Hypoxemic Neurological Damages in Neonates With Congenital Heart Defects?. Frontiers in Pharmacology 12.
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Kai-Uwe Eckardt, Rajiv Agarwal, Youssef Mk Farag, Alan G Jardine, Zeeshan Khawaja, Mark J Koury, Wenli Luo, Kunihiro Matsushita, Peter A McCullough, Patrick Parfrey, Geoffrey Ross, Mark J Sarnak, Dennis Vargo, Wolfgang C Winkelmayer & Glenn M Chertow. (2021) Global Phase 3 programme of vadadustat for treatment of anaemia of chronic kidney disease: rationale, study design and baseline characteristics of dialysis-dependent patients in the INNO2VATE trials. Nephrology Dialysis Transplantation 36:11, pages 2039-2048.
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Chun Pan, Minghao Yan, Haibo Jin, Hongqian Guo & Xiaodong Han. (2021) Chronic exposure to MC-LR increases the risks of microcytic anemia: Evidence from human and mice. Environmental Pollution 288, pages 117966.
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Min Min Than, Pimpisid Koonyosying, Jetsada Ruangsuriya, Sunhawit Junrungsee, Chairat Uthaipibull & Somdet Srichairatanakool. (2021) Effect of Recombinant Human Erythroferrone Protein on Hepcidin Gene (Hamp1) Expression in HepG2 and HuH7 Cells. Materials 14:21, pages 6480.
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Edward X. Han, Hong Qian, Bo Jiang, Maria Figetakis, Natalia Kosyakova, George Tellides, Laura E. Niklason & William G. Chang. (2021) A therapeutic vascular conduit to support in vivo cell-secreted therapy. npj Regenerative Medicine 6:1.
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Jana Tomc & Nataša Debeljak. (2021) Molecular Insights into the Oxygen-Sensing Pathway and Erythropoietin Expression Regulation in Erythropoiesis. International Journal of Molecular Sciences 22:13, pages 7074.
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Glenn M. Chertow, Pablo E. Pergola, Rajiv Agarwal, Geoffrey A. Block, Youssef M.K. Farag, Alan G. Jardine, Mark J. Koury, Wenli Luo, Zeeshan Khawaja, Eldrin F. Lewis, Kunihiro Matsushita, Peter A. McCullough, Patrick S. Parfrey, Janet Wittes, Kimberly A. Walters, Carol Tseng, Tim Lin, Mark J. Sarnak, Dennis L. Vargo, Wolfgang C. Winkelmayer & Kai-Uwe Eckardt. (2021) Cardiovascular safety and efficacy of vadadustat for the treatment of anemia in non-dialysis-dependent CKD: Design and baseline characteristics. American Heart Journal 235, pages 1-11.
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Martin W. Schoen, Shamia Hoque, Bartlett J. Witherspoon, Benjamin Schooley, Oliver Sartor, Y. Tony Yang, Paul R. Yarnold, Kevin B. Knopf, William J.M. Hrushesky, Michael Dickson, Brian J. Chen, Chadi Nabhan & Charles L. Bennett. (2020) End of an era for erythropoiesis‐stimulating agents in oncology. International Journal of Cancer 146:10, pages 2829-2835.
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Matthew A. Held, Emily Greenfest-Allen, Su Su, Christian J. Stoeckert, Matthew P. Stokes & Don M. Wojchowski. (2020) Phospho-PTM proteomic discovery of novel EPO- modulated kinases and phosphatases, including PTPN18 as a positive regulator of EPOR/JAK2 Signaling. Cellular Signalling 69, pages 109554.
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Gudjon R. Oskarsson, Asmundur Oddsson, Magnus K. Magnusson, Ragnar P. Kristjansson, Gisli H. Halldorsson, Egil Ferkingstad, Florian Zink, Anna Helgadottir, Erna V. Ivarsdottir, Gudny A. Arnadottir, Brynjar O. Jensson, Hildigunnur Katrinardottir, Gardar Sveinbjornsson, Anna M. Kristinsdottir, Amy L. Lee, Jona Saemundsdottir, Lilja Stefansdottir, Jon K. Sigurdsson, Olafur B. Davidsson, Stefania Benonisdottir, Aslaug Jonasdottir, Adalbjorg Jonasdottir, Stefan Jonsson, Reynir L. Gudmundsson, Folkert W. Asselbergs, Vinicius Tragante, Bjarni Gunnarsson, Gisli Masson, Gudmar Thorleifsson, Thorunn Rafnar, Hilma Holm, Isleifur Olafsson, Pall T. Onundarson, Daniel F. Gudbjartsson, Gudmundur L. Norddahl, Unnur Thorsteinsdottir, Patrick Sulem & Kari Stefansson. (2020) Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis. Communications Biology 3:1.
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Matthew A. Held, Emily Greenfest-Allen, Edward Jachimowicz, Christian J. Stoeckert, Matthew P. Stokes, Antony W. Wood & Don M. Wojchowski. (2020) Phospho-proteomic discovery of novel signal transducers including thioredoxin-interacting protein as mediators of erythropoietin-dependent human erythropoiesis. Experimental Hematology 84, pages 29-44.
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Senthil Velan Bhoopalan, Lily Jun-shen Huang & Mitchell J. Weiss. (2020) Erythropoietin regulation of red blood cell production: from bench to bedside and back. F1000Research 9, pages 1153.
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Yansheng Wu, Qiang Wan, Liqiang Shi, Jiaoying Ou, YingQiao Li, Fei He, Huiling Wang & Jiandong Gao. (2019) Siwu Granules and Erythropoietin Synergistically Ameliorated Anemia in Adenine-Induced Chronic Renal Failure Rats. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-12.
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Franco Musio. (2019) Kidney Disease and Anemia in Elderly Patients. Clinics in Geriatric Medicine 35:3, pages 327-337.
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Martha Catalina Rivera-Cervantes, José Jaime Jarero-Basulto, Justo Murguía-Castillo, Alejandra Guadalupe Marín-López, Yadira Gasca-Martínez, Sergio Cornelio-Martínez & Carlos Beas-Zárate. (2019) The Recombinant Human Erythropoietin Administered in Neonatal Rats After Excitotoxic Damage Induces Molecular Changes in the Hippocampus. Frontiers in Neuroscience 13.
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Tzu-Lin Chen, Ya-Wen Chiang, Guan-Ling Lin, Hsin-Hou Chang, Te-Sheng Lien, Min-Hua Sheh & Der-Shan Sun. (2018) Different effects of granulocyte colony-stimulating factor and erythropoietin on erythropoiesis. Stem Cell Research & Therapy 9:1.
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Linus Kebschull, Leon Franz Christoph Theilmann, Annika Mohr, Wencke Uennigmann, Sandra Stoeppeler, Barbara Heitplatz, Hans-Ullrich Spiegel, Ralf Bahde, Daniel Michael Palmes & Felix Becker. (2017) EPOR2/βcR2-independendent effects of low-dose epoetin- α in porcine liver transplantation . Bioscience Reports 37:6.
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Feng Zhao, Yijuan Wang, Lin Liu & Meiling Bian. (2017) Erythropoietin for cancer-associated malignant anemia: A meta-analysis. Molecular and Clinical Oncology 6:6, pages 925-930.
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Dong-Xue Zhang, Li-Min Zhang, Xiao-Chun Zhao & Wenbo Sun. (2017) Neuroprotective effects of erythropoietin against sevoflurane-induced neuronal apoptosis in primary rat cortical neurons involving the EPOR-Erk1/2-Nrf2/Bach1 signal pathway. Biomedicine & Pharmacotherapy 87, pages 332-341.
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Rakesh Verma, Jennifer M. Green, Peter J. Schatz & Don M. Wojchowski. (2016) A dimeric peptide with erythropoiesis-stimulating activity uniquely affects erythropoietin receptor ligation and cell surface expression. Experimental Hematology 44:8, pages 765-769.e1.
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