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Review

Targeting apoptosis in cancer chemotherapy

Pages 73-84 | Published online: 25 Feb 2005

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Zahra Amirghofran, Masoud Bahmani, Abbas Azadmehr, Elham Ashouri & Katayoun Javidnia. (2007) Antitumor Activity and Apoptosis Induction in Human Cancer Cell Lines by Dionysia termeana. Cancer Investigation 25:7, pages 550-554.
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Articles from other publishers (35)

Yin-Peng Bai, Cheng-Jie Yang, Nan Deng, Mi Zhang, Zhi-Jun Zhang, Lei Li, Yong Zhou, Xiong-Fei Luo, Chuan-Rui Xu, Bao-Qi Zhang, Yue Ma & Ying-Qian Liu. (2022) Design and synthesis of novel 7-ethyl-10-fluoro-20-O-(cinnamic acid ester)-camptothecin derivatives as potential high selectivity and low toxicity topoisomerase I inhibitors for hepatocellular carcinoma. Biochemical Pharmacology 200, pages 115049.
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Athanasios Papastathopoulos, Nikolaos Lougiakis, Ioannis K. Kostakis, Panagiotis Marakos, Nicole Pouli, Harris Pratsinis & Dimitris Kletsas. (2021) New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships. European Journal of Medicinal Chemistry 218, pages 113387.
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Yixin Tong, Yuan Huang, Yuchao Zhang, Xiangtai Zeng, Mei Yan, Zhongsheng Xia & Dongming Lai. (2021) DPP3/CDK1 contributes to the progression of colorectal cancer through regulating cell proliferation, cell apoptosis, and cell migration. Cell Death & Disease 12:6.
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Jinsun Kim, Sung Hee Hong, So Hyun Jeon, Min Ho Park & Cha-Gyun Shin. (2021) The Novel Benzothiazole Derivative PB11 Induces Apoptosis via the PI3K/AKT Signaling Pathway in Human Cancer Cell Lines. International Journal of Molecular Sciences 22:5, pages 2718.
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Choo, Loh & Chen. (2019) Destined to Die: Apoptosis and Pediatric Cancers. Cancers 11:11, pages 1623.
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Yuyi Wang, Chi Du, Nan Zhang, Mei Li, Yanyang Liu, Maoyuan Zhao, Feng Wang & Feng Luo. (2018) TGF‑β1 mediates the effects of aspirin on colonic tumor cell proliferation and apoptosis. Oncology Letters.
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Ji Yang, Yue Wu, Xiao Wang, Liqian Xu, Xiaohong Zhao & Yunmei Yang. (2017) Chemoresistance is associated with overexpression of HAX-1, inhibition of which resensitizes drug-resistant breast cancer cells to chemotherapy. Tumor Biology 39:3, pages 101042831769222.
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Sayer I Al-Azzam, Banan T Awawdeh, Karem H Alzoubi, Yousef S Khader & Ahmed M Alkafajei. (2014) Compliance with safe handling guidelines of antineoplastic drugs in Jordanian hospitals. Journal of Oncology Pharmacy Practice 21:1, pages 3-9.
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Gunasekar Manoharan, Seema R. Jaiswal & Jaipaul Singh. (2013) Effect of α, β momorcharin on viability, caspase activity, cytochrome c release and on cytosolic calcium levels in different cancer cell lines. Molecular and Cellular Biochemistry 388:1-2, pages 233-240.
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MOHAMMAD AKBAR HOSSAIN, DONG HWAN KIM, JUNG YOON JANG, YONG JUNG KANG, JEONG-HYUN YOON, JEON-OK MOON, HAE YOUNG CHUNG, GI-YOUNG KIM, YUNG HYUN CHOI, BRYAN L. COPPLE & NAM DEUK KIM. (2012) Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model. International Journal of Oncology 40:4, pages 1298-1304.
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Sarah Jane Lunt, Simon Akerman, Sally A. Hill, Matthew Fisher, Victoria J. Wright, Constantino C. Reyes‐Aldasoro, Gillian M. Tozer & Chryso Kanthou. (2011) Vascular effects dominate solid tumor response to treatment with combretastatin A‐4‐phosphate. International Journal of Cancer 129:8, pages 1979-1989.
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Hui Liu, Cheng-Kun Qin, Guo-Qing Han, Hong-Wei Xu, Wan-Hua Ren & Cheng-Yong Qin. (2008) Synthetic chenodeoxycholic acid derivative, HS-1200, induces apoptosis of human hepatoma cells via a mitochondrial pathway. Cancer Letters 270:2, pages 242-249.
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Constance J. Glover, Alfred A. Rabow, Yasemin G. Isgor, Robert H. Shoemaker & David G. Covell. (2007) Data mining of NCI's anticancer screening database reveals mitochondrial complex I inhibitors cytotoxic to leukemia cell lines. Biochemical Pharmacology 73:3, pages 331-340.
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Eung-Ryoung Lee, Jang-Yong Kim, Yong-Jin Kang, Jae-Yeon Ahn, Jung-Hyun Kim, Bong-Woo Kim, Hye-Yeon Choi, Mi-Young Jeong & Ssang-Goo Cho. (2006) Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1763:9, pages 958-968.
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Judy E. Anderson, Lise Lotte Hansen, Frank C. Mooren, Markus Post, Hubert Hug, Anne Zuse & Marek Los. (2006) Methods and biomarkers for the diagnosis and prognosis of cancer and other diseases: Towards personalized medicine. Drug Resistance Updates 9:4-5, pages 198-210.
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Joseph Moore, Karen Seiter, Jonathan Kolitz, Wendy Stock, Francis Giles, Matt Kalaycio, David Zenk & Guido Marcucci. (2006) A Phase II study of Bcl-2 antisense (oblimersen sodium) combined with gemtuzumab ozogamicin in older patients with acute myeloid leukemia in first relapse. Leukemia Research 30:7, pages 777-783.
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Eva Galeano, Elena Nieto, Ana Isabel García-Pérez, M.Dolores Delgado, Montserrat Pinilla & Pilar Sancho. (2005) Effects of the antitumoural dequalinium on NB4 and K562 human leukemia cell lines. Leukemia Research 29:10, pages 1201-1211.
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Andriy M. Babsky, Shahryar K. Hekmatyar, Hong Zhang, James L. Solomon & Navin Bansal. (2005) Application of 23Na MRI to Monitor Chemotherapeutic Response in RIF-1 Tumors. Neoplasia 7:7, pages 658-666.
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Yu-Chi Wang, Ru-Huei Fu, Hsyue-Jen Hsieh, Hsiang-Tai Chao & Shu-Huei Kao. (2005) Polyglycolic acid/chitosan glue and apoptosis of endometriotic cells. Fertility and Sterility 84:1, pages 75-81.
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Nadia Sabatini, Viviana Di Giacomo, Monica Rapino, Rosalba Rana, Francesco Giuseppe & Amelia Cataldi. (2005) JNK/p53 mediated cell death response in K562 exposed to etoposide-ionizing radiation combined treatment. Journal of Cellular Biochemistry 95:3, pages 611-619.
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Mark R. Lackner, Rachel M. Kindt, Pamela M. Carroll, Katherine Brown, Michael R. Cancilla, Changyou Chen, Heshani de Silva, Yvonne Franke, Bo Guan, Tim Heuer, Tak Hung, Kevin Keegan, Jae Moon Lee, Veeraswamy Manne, Carol O’Brien, Dianne Parry, Juan J. Perez-Villar, Rajashekar K. Reddy, Hong Xiao, Hangjun Zhan, Mark Cockett, Greg Plowman, Kevin Fitzgerald, Michael Costa & Petra Ross-Macdonald. (2005) Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors. Cancer Cell 7:4, pages 325-336.
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JungSan Chang, YaLing Hsu, PoLin Kuo, YuChun Kuo, LienChai Chiang & ChunChing Lin. (2005) Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line. Life Sciences 76:16, pages 1883-1893.
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Goran BrajuskovicR.R.. (2005) Apoptosis in malignant diseases. Archive of Oncology Arhiv za onkologiju 13:1, pages 19-22.
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Victor D. Schepkin, Brian D. Ross, Thomas L. Chenevert, Alnawaz Rehemtulla, Surabhi Sharma, Mahesh Kumar & Jadranka Stojanovska. (2004) Sodium magnetic resonance imaging of chemotherapeutic response in a rat glioma. Magnetic Resonance in Medicine 53:1, pages 85-92.
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Goran BrajuskovicR.R., Andjelija Milic-Skaro, Snezana CerovicJ.J., Slobodan MarjanovicA.A., Slavica Usaj-Knezevic, Milica Cizmic & Jovan Dimitrijevic. (2004) Familija Bcl 2 proteina kod malignih bolesti. Vojnosanitetski pregled 61:3, pages 305-310.
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Suxing Liu, W.Robert Bishop & Ming Liu. (2003) Differential effects of cell cycle regulatory protein p21WAF1/Cip1 on apoptosis and sensitivity to cancer chemotherapy. Drug Resistance Updates 6:4, pages 183-195.
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Cheryl Brantley-Finley, Christopher S. Lyle, Lihua Du, Mary E. Goodwin, Toria Hall, Dominika Szwedo, G.P. Kaushal & Timothy C. Chambers. (2003) The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. Biochemical Pharmacology 66:3, pages 459-469.
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Christiane Thallinger, Markus F. Wolschek, Volker Wacheck, Helmut Maierhofer, Patrick Günsberg, Peter Polterauer, Hubert Pehamberger, Brett P. Monia, Edgar Selzer, Klaus Wolff & Burkhard Jansen. (2003) Mcl-1 Antisense Therapy Chemosensitizes Human Melanoma in a SCID Mouse Xenotransplantation Model. Journal of Investigative Dermatology 120:6, pages 1081-1086.
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Geza Acs, Paul J. Zhang, Cindy M. McGrath, Peter Acs, John McBroom, Ahmed Mohyeldin, Suzhen Liu, Huasheng Lu & Ajay Verma. (2003) Hypoxia-Inducible Erythropoietin Signaling in Squamous Dysplasia and Squamous Cell Carcinoma of the Uterine Cervix and Its Potential Role in Cervical Carcinogenesis and Tumor Progression. The American Journal of Pathology 162:6, pages 1789-1806.
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Anna K. Nowak, Richard A. Lake, Amanda L. Marzo, Bernadette Scott, William R. Heath, Edward J. Collins, Jeffrey A. Frelinger & Bruce W. S. Robinson. (2003) Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T Cells. The Journal of Immunology 170:10, pages 4905-4913.
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Philip J Bergman. (2003) Mechanisms of anticancer drug resistance. Veterinary Clinics of North America: Small Animal Practice 33:3, pages 651-667.
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Yingchang Mi, Shelia D. Thomas, Xiaohua Xu, Lavona K. Casson, Donald M. Miller & Paula J. Bates. (2003) Apoptosis in Leukemia Cells Is Accompanied by Alterations in the Levels and Localization of Nucleolin. Journal of Biological Chemistry 278:10, pages 8572-8579.
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Sonam Dolma, Stephen L Lessnick, William C Hahn & Brent R Stockwell. (2003) Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell 3:3, pages 285-296.
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A. Paradiso, S. Volpe, A. Iacobacci, E. Marubini, P. Verderio, A. Costa, M.G. Daidone, A. Marchetti, M. Mottolese, D. Amadori, F. De Paola, L. Saragoni, L. Medri, I. Nenci, P. Querzoli, M. Gion, R. Dittadi, M. Plebani, C. Orlando, G. Bevilacqua & R. Silvestrini. (2018) Quality Control for Biomarker Determination in Oncology: The Experience of the Italian Network for Quality Assessment of Tumor Biomarkers (INQAT). The International Journal of Biological Markers 17:3, pages 201-214.
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Yin-Peng Bai, Cheng-Jie Yang, Nan Deng, Mi Zhang, Zhi-Jun Zhang, Lei Li, Ying-Qian Liu & Chuan-Rui Xu. (2022) Design and Synthesis of Novel 7-Ethyl-10-Fluoro-20-O-(Cinnamic Acid Ester)-Camptothecin Derivatives as Potential High Selectivity and Low Toxicity Topoisomerase I Inhibitors for Hepatocellular Carcinoma. SSRN Electronic Journal.
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