Citations (75)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Linda S. Steelman, Patrick Navolanic, William H. Chappell, Stephen L. Abrams, Ellis W.T. Wong, Alberto M. Martelli, Lucio Cocco, Franca Stivala, Massimo Libra, Ferdinando Nicoletti, Lyudmyla B. Drobot, Richard A. Franklin & James A. McCubrey. (2011) Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells. Cell Cycle 10:17, pages 3003-3015.
Read now
Read now
James A McCubrey, Linda S Steelman, Steven L Abrams, William H Chappell, Suzanne Russo, Roger Ove, Michele Milella, Agostino Tafuri, Paolo Lunghi, Antonio Bonati, Franca Stivala, Ferdinando Nicoletti, Massimo Libra, Alberto M Martelli, Giuseppe Montalto & Melchiorre Cervello. (2010) Emerging MEK inhibitors. Expert Opinion on Emerging Drugs 15:2, pages 203-223.
Read now
Read now
Linda S Steelman, Kristin M Stadelman, William H Chappell, Stefan Horn, Jörg Bäsecke, Melchiorre Cervello, Ferdinando Nicoletti, Massimo Libra, Franca Stivala, Alberto M Martelli & James A McCubrey. (2008) Akt as a therapeutic target in cancer. Expert Opinion on Therapeutic Targets 12:9, pages 1139-1165.
Read now
Read now
John G Shelton, Linda S Steelman, Steve L Abrams, Fred E Bertrand, Richard A Franklin, Martin McMahon & James A McCubrey. (2005) The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what’s genetics got to do with it?. Expert Opinion on Therapeutic Targets 9:5, pages 1009-1030.
Read now
Read now
Susanne J Rogers, Carol Box, Kevin J Harrington, Chris Nutting, Peter Rhys-Evans & Suzanne A Eccles. (2005) The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck. Expert Opinion on Therapeutic Targets 9:4, pages 769-790.
Read now
Read now
Articles from other publishers (70)
Mohammad Malekan, Mohammad Ali Ebrahimzadeh & Fateme Sheida. (2021) The role of Hypoxia-Inducible Factor-1alpha and its signaling in melanoma. Biomedicine & Pharmacotherapy 141, pages 111873.
Crossref
Crossref
Jian Sun, Shugen Li, Fei Wang, Caibin Fan & Jianqing Wang. (2019) Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis. BMC Medical Genetics 20:1.
Crossref
Crossref
Virginia Álvarez-Garcia, Yasmine Tawil, Helen M. Wise & Nicholas R. Leslie. (2019) Mechanisms of PTEN loss in cancer: It’s all about diversity. Seminars in Cancer Biology 59, pages 66-79.
Crossref
Crossref
Huihui Ma, Zhen Wang, Lei Hu, Shangrong Zhang, Chenggang Zhao, Haoran Yang, Hongzhi Wang, Zhiyou Fang, Lijun Wu & Xueran Chen. (2018) The melatonin-MT1 receptor axis modulates tumor growth in PTEN-mutated gliomas. Biochemical and Biophysical Research Communications 496:4, pages 1322-1330.
Crossref
Crossref
Tianfang Yang, Matthew Moore & Fenglei He. (2018) Pten regulates neural crest proliferation and differentiation during mouse craniofacial development. Developmental Dynamics 247:2, pages 304-314.
Crossref
Crossref
Sandeep Kumar, Bhoomika Sharma, Priyanka Bhadwal, Prerna Sharma & Navneet Agnihotri. 2018. Therapeutic Foods. Therapeutic Foods
51
98
.
Xindong Zhang, Lin Gao & Songwei Jia. (2017) Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer. Molecules 23:1, pages 39.
Crossref
Crossref
Ksymena Urbanek, Marta Lesiak, Daniel Krakowian, Halina Koryciak-Komarska, Wirginia Likus, Piotr Czekaj, Damian Kusz & Aleksander L Sieroń. (2017) Notch signaling pathway and gene expression profiles during early in vitro differentiation of liver-derived mesenchymal stromal cells to osteoblasts. Laboratory Investigation 97:10, pages 1225-1234.
Crossref
Crossref
Maria Rosaria Ricciardi, Simone Mirabilii, Roberto Licchetta, Monica Piedimonte & Agostino Tafuri. (2017) Targeting the Akt, GSK-3, Bcl-2 axis in acute myeloid leukemia. Advances in Biological Regulation 65, pages 36-58.
Crossref
Crossref
Feng Tian, Yong Han, Xiaolong Yan, Daixing Zhong, Guang Yang, Jie Lei, Xiaofei Li & Xiaoping Wang. (2015)
Upregulation of microrna‐451 increases the sensitivity of
A
549 cells to radiotherapy through enhancement of apoptosis
. Thoracic Cancer 7:2, pages 226-231.
Crossref
Crossref
Kyung-Ran Park, Hyung-Mun Yun, Tran-Hong Quang, Hyuncheol Oh, Dong-Sung Lee, Q-Schick Auh & Eun-Cheol Kim. (2016)
4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells
in vitro
and
in vivo
xenograft model through down-regulation of the JAK2/STAT3 pathway
. Oncotarget 7:6, pages 6960-6971.
Crossref
Crossref
Anne E Sarver & Subbaya Subramanian. (2015) MicroRNAs in the pathobiology of sarcomas. Laboratory Investigation 95:9, pages 987-994.
Crossref
Crossref
XIAN YU, ZHENGMIN XU, JUN LEI, TINGTING LI & YAN WANG. (2015) VP22 mediates intercellular trafficking and enhances the in vitro antitumor activity of PTEN. Molecular Medicine Reports 12:1, pages 1286-1290.
Crossref
Crossref
Eun Shin, Chang Min Choi, Hyeong Ryul Kim, Se Jin Jang & Young Soo Park. (2015) Immunohistochemical characterization of the mTOR pathway in stage-I non-small-cell lung carcinoma. Lung Cancer 89:1, pages 13-18.
Crossref
Crossref
Renuka, Sandeep Kumar, Bhoomika Sharma, Prerna Sharma & Navneet Agnihotri. (2015) n-3 PUFAs: an Elixir in Prevention of Colorectal Cancer. Current Colorectal Cancer Reports 11:3, pages 141-149.
Crossref
Crossref
Cheng Chen, Huijuan Mao, Xiangbo Yu, Bin Sun, Ming Zeng, Xiufen Zhao, Jun Qian, Jia Liu & Changying Xing. (2015) Effect of secondary hyperparathyroidism serum on endothelial cells and intervention with Klotho. Molecular Medicine Reports.
Crossref
Crossref
Xianglan Zhang, Ji Soo Park, Kyu Hyun Park, Ki Hyang Kim, Minkyu Jung, Hyun Cheol Chung, Sun Young Rha & Hyo Song Kim. (2015) PTEN Deficiency as a Predictive Biomarker of Resistance to HER2-Targeted Therapy in Advanced Gastric Cancer. Oncology 88:2, pages 76-85.
Crossref
Crossref
Fred E. Bertrand, James A. McCubrey, C. William Angus, Jennifer M. Nutter & George Sigounas. (2014) NOTCH and PTEN in prostate cancer. Advances in Biological Regulation 56, pages 51-65.
Crossref
Crossref
Lei Chang, Peter H. Graham, Jingli Hao, Joseph Bucci, Paul J. Cozzi, John H. Kearsley & Yong Li. (2014) Emerging roles of radioresistance in prostate cancer metastasis and radiation therapy. Cancer and Metastasis Reviews 33:2-3, pages 469-496.
Crossref
Crossref
Sakthivel Muniyan, Matthew A. Ingersoll, Surinder K. Batra & Ming-Fong Lin. (2014) Cellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressor. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1846:1, pages 88-98.
Crossref
Crossref
Yonghwan Kim & Youngdae Yoon. (2014) Elucidation of different inhibition mechanism of small chemicals on PtdInsP-binding domains using in silico docking experiments. Bioorganic & Medicinal Chemistry Letters 24:10, pages 2256-2262.
Crossref
Crossref
Youngdae Yoon. (2014) Small chemicals with inhibitory effects on PtdIns(3,4,5)P3 binding of Btk PH domain. Bioorganic & Medicinal Chemistry Letters 24:10, pages 2334-2339.
Crossref
Crossref
Shevali Kansal, Archana Bhatnagar & Navneet Agnihotri. (2014) Fish Oil Suppresses Cell Growth and Metastatic Potential by Regulating PTEN and NF-κB Signaling in Colorectal Cancer. PLoS ONE 9:1, pages e84627.
Crossref
Crossref
A. Mortlock, K. Foote, J. Kettle & B. Aquila. 2014. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering.
Furong Dai, Yi Zhang, Xin Zhu, Nianchun Shan & Yuxiang Chen. (2013) The anti-chemoresistant effect and mechanism of MUC1 aptamer–miR-29b chimera in ovarian cancer. Gynecologic Oncology 131:2, pages 451-459.
Crossref
Crossref
Yuesi Zhong, Jian Yan, Meihai Deng, Kunpeng Hu, Zhicheng Yao, Yong Zou & Ruiyun Xu. (2013) Impaired phosphate and tension homologue deleted on chromosome 10 expression and its prognostic role in radical surgery for hepatocellular carcinoma with family aggregation resulting from hepatitis B and liver cirrhosis. Experimental Biology and Medicine 238:8, pages 866-873.
Crossref
Crossref
Xue Dong, Lu‐Gang Yu, Rong Sun, Yan‐Na Cheng, Hua Cao, Kang‐Min Yang, Yi‐Ning Dong, Yan Wu & Xiu‐Li Guo. (2012) Inhibition of PTEN expression and activity by angiotensin II induces proliferation and migration of vascular smooth muscle cells. Journal of Cellular Biochemistry 114:1, pages 174-182.
Crossref
Crossref
Mm Sun, Mz Zhang, Y Chen, Sl Li, W Zhang, Gw Ya & Ks Chen. (2012) Effect of PTEN Antisense Oligonucleotide on Oesophageal Squamous Cell Carcinoma Cell Lines. Journal of International Medical Research 40:6, pages 2098-2108.
Crossref
Crossref
James A. McCubrey, Linda S. Steelman, William H. Chappell, Stephen L. Abrams, Giuseppe Montalto, Melchiorre Cervello, Ferdinando Nicoletti, Paolo Fagone, Grazia Malaponte, Maria C. Mazzarino, Saverio Candido, Massimo Libra, Jörg Bäsecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Michele Milella, Agostino Tafuri, Lucio Cocco, Camilla Evangelisti, Francesca Chiarini & Alberto M. Martelli. (2012) Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response.. Oncotarget 3:9, pages 954-987.
Crossref
Crossref
Xianwei Wang, Jianfeng Zhao, Jianhua Huang, Huihuan Tang, Shuyi Yu & Yuxiang Chen. (2012) The regulatory roles of miRNA and methylation on oncogene and tumor suppressor gene expression in pancreatic cancer cells. Biochemical and Biophysical Research Communications 425:1, pages 51-57.
Crossref
Crossref
Yu Zhang, Xiuwu Zhang, Zahid N. Rabbani, Isabel L. Jackson & Zeljko Vujaskovic. (2012) Oxidative Stress Mediates Radiation Lung Injury by Inducing Apoptosis. International Journal of Radiation Oncology*Biology*Physics 83:2, pages 740-748.
Crossref
Crossref
Gang LiJingfeng ZhaoXianjing PengJian LiangXin DengYuxiang Chen. (2012) Radiation/Paclitaxel Treatment of p53-Abnormal Non-Small Cell Lung Cancer Xenograft Tumor and Associated Mechanism. Cancer Biotherapy and Radiopharmaceuticals 27:4, pages 227-233.
Crossref
Crossref
Liang Wang, Wentao Yue, Lina Zhang, Xiaoting Zhao, Yue Wang & Shaofa Xu. (2011) mTOR and PTEN expression in non-small cell lung cancer: analysis by real-time fluorescence quantitative polymerase chain reaction and immunohistochemistry. Surgery Today 42:5, pages 419-425.
Crossref
Crossref
Gang Li, Jingfeng Zhao, Xianjing Peng, Jian Liang, Xin Deng & Yuxiang Chen. (2012) The mechanism involved in the loss of PTEN expression in NSCLC tumor cells. Biochemical and Biophysical Research Communications 418:3, pages 547-552.
Crossref
Crossref
Marco A. De Velasco & Hirotsugu Uemura. (2012) Preclinical Remodeling of Human Prostate Cancer through the PTEN/AKT Pathway. Advances in Urology 2012, pages 1-12.
Crossref
Crossref
James A. McCubrey, Stephen L. Abrams, Kazuo Umezawa, Lucio Cocco, Alberto M. Martelli, Richard A. Franklin, William H. Chappell & Linda S. Steelman. (2012) Novel approaches to target cancer initiating cells–Eliminating the root of the cancer. Advances in Biological Regulation 52:1, pages 249-264.
Crossref
Crossref
James A. McCubrey, Linda S. Steelman, C. Ruth Kempf, William H. Chappell, Stephen L. Abrams, Franca Stivala, Graziella Malaponte, Ferdinando Nicoletti, Massimo Libra, Jörg Bäsecke, Danijela Maksimovic-Ivanic, Sanja Mijatovic, Giuseppe Montalto, Melchiorre Cervello, Lucio Cocco & Alberto M. Martelli. (2011) Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways. Journal of Cellular Physiology 226:11, pages 2762-2781.
Crossref
Crossref
Yoshihiro Maekawa, Mitsuru Ohishi, Masashi Ikushima, Koichi Yamamoto, Osamu Yasuda, Ryosuke Oguro, Hiroko Yamamoto-Hanasaki, Yuji Tatara, Yasushi Takeya & Hiromi Rakugi. (2011) Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway. Geriatrics & Gerontology International 11:4, pages 510-516.
Crossref
Crossref
Jackson R. Taylor, Brian D. Lehmann, William H. Chappell, Stephen L. Abrams, Linda S. Steelman & James A. McCubrey. (2011) Cooperative Effects of Akt-1 and Raf-1 on the Induction of Cellular Senescence in Doxorubicin or Tamoxifen Treated Breast Cancer Cells. Oncotarget 2:8, pages 610-626.
Crossref
Crossref
Melissa L. SokoloskyKristin M. StadelmanWilliam H. Chappell, Stephen L. Abrams, Alberto M. Martelli, Franca Stivala, Massimo Libra, Ferdinando Nicoletti, Lyudmyla B. Drobot, Richard A. Franklin, Linda S. Steelman & James A. McCubrey. (2011) Involvement of Akt-1 and mTOR in Sensitivity of Breast Cancer to Targeted Therapy. Oncotarget 2:7, pages 538-550.
Crossref
Crossref
A M Martelli, C Evangelisti, W Chappell, S L Abrams, J Bäsecke, F Stivala, M Donia, P Fagone, F Nicoletti, M Libra, V Ruvolo, P Ruvolo, C R Kempf, L S Steelman & J A McCubrey. (2011) Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway. Leukemia 25:7, pages 1064-1079.
Crossref
Crossref
Linda S. Steelman, William H. Chappell, Stephen L. Abrams, C. Ruth Kempf, Jacquelyn Long, Piotr Laidler, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Franca Stivala, Maria C. Mazzarino, Marco Donia, Paolo Fagone, Graziella Malaponte, Ferdinando Nicoletti, Massimo Libra, Michele Milella, Agostino Tafuri, Antonio Bonati, Jörg Bäsecke, Lucio Cocco, Camilla Evangelisti, Alberto M. Martelli, Giuseppe Montalto, Melchiorre Cervello & James A. McCubrey. (2011) Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging. Aging 3:3, pages 192-222.
Crossref
Crossref
James A. McCubrey, William H. Chappell, Stephen L. Abrams, Richard A. Franklin, Jacquelyn M. Long, Jennifer A. Sattler, C. Ruth Kempf, Piotr Laidler & Linda S. Steelman. (2011) Targeting the cancer initiating cell: The Achilles’ heel of cancer. Advances in Enzyme Regulation 51:1, pages 152-162.
Crossref
Crossref
Michelle A. Lee, Nathan J. Robison, Susan N. Chi, Sridharan Gururangan & Mark W. Kieran. 2011. Primary Central Nervous System Tumors. Primary Central Nervous System Tumors
285
332
.
Charles J Rosser, Micah Gaar & Stacy Porvasnik. (2009) Molecular fingerprinting of radiation resistant tumors: Can we apprehend and rehabilitate the suspects?. BMC Cancer 9:1.
Crossref
Crossref
Anil Kumar, Helen L. Fillmore, Renu Kadian, William C. Broaddus, Gary W. Tye & Timothy E. Van Meter. (2009) The Alkylphospholipid Perifosine Induces Apoptosis and p21-Mediated Cell Cycle Arrest in Medulloblastoma. Molecular Cancer Research 7:11, pages 1813-1821.
Crossref
Crossref
A Metzner, C Precht, B Fehse, W Fiedler, C Stocking, A Günther, G W Mayr & M Jücker. (2009) Reduced proliferation of CD34+ cells from patients with acute myeloid leukemia after gene transfer of INPP5D. Gene Therapy 16:4, pages 570-573.
Crossref
Crossref
L S Steelman, P M Navolanic, M L Sokolosky, J R Taylor, B D Lehmann, W H Chappell, S L Abrams, E W T Wong, K M Stadelman, D M Terrian, N R Leslie, A M Martelli, F Stivala, M Libra, R A Franklin & J A McCubrey. (2008) Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors. Oncogene 27:29, pages 4086-4095.
Crossref
Crossref
J A McCubrey, L S Steelman, S L Abrams, F E Bertrand, D E Ludwig, J Bäsecke, M Libra, F Stivala, M Milella, A Tafuri, P Lunghi, A Bonati & A M Martelli. (2008) Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. Leukemia 22:4, pages 708-722.
Crossref
Crossref
L S Steelman, S L Abrams, J Whelan, F E Bertrand, D E Ludwig, J Bäsecke, M Libra, F Stivala, M Milella, A Tafuri, P Lunghi, A Bonati, A M Martelli & J A McCubrey. (2008) Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. Leukemia 22:4, pages 686-707.
Crossref
Crossref
Kyoung-Won Cho, Sung-Won Cho, Jong-Min Lee, Min-Jung Lee, Hee-Seok Gang & Han-Sung Jung. (2008) Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expression Patterns 8:4, pages 284-290.
Crossref
Crossref
Pablo Lopez-Bergami, Boris Fitchman & Ze’ev Ronai. (2008) Understanding Signaling Cascades in Melanoma. Photochemistry and Photobiology 84:2, pages 289-306.
Crossref
Crossref
James A. McCubrey, Melissa L. Sokolosky, Brian D. Lehmann, Jackson R. Taylor, Patrick M. Navolanic, William H. Chappell, Stephen L. Abrams, Kristin M. Stadelman, Ellis W.T. Wong, Negin Misaghian, Stefan Horn, Jörg Bäsecke, Massimo Libra, Franca Stivala, Giovanni Ligresti, Agostino Tafuri, Michele Milella, Marek Zarzycki, Andrzej Dzugaj, Francesca Chiarini, Camilla Evangelisti, Alberto M. Martelli, David M. Terrian, Richard A. Franklin & Linda S. Steelman. (2008) Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy. Advances in Enzyme Regulation 48:1, pages 113-135.
Crossref
Crossref
James A. McCubrey, Richard A. Franklin, Fred E. Bertrand, Jackson R. Taylor, William H. Chappell, Melissa L. Midgett, Ellis W. T. Wong, Stephen L. Abrams, Kristin M. Stadelman, Negin Misaghian, Dale L. Ludwig, Jorg Basecke, Massimo Libra, Franca Stivala, Michele Milella, Agostino Tafuri, Alberto M. Martelli, Paolo Lungi, Antonio Bonati, David M. Terrian, Brian D. Lehmann & Linda S. Steelman. 2008. Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy. Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy
81
114
.
Marleen Van Troys, Joël Vandekerckhove & Christophe Ampe. 2008. Actin-Binding Proteins and Disease. Actin-Binding Proteins and Disease
229
277
.
James A. McCubrey, Linda S. Steelman, William H. Chappell, Stephen L. Abrams, Ellis W.T. Wong, Fumin Chang, Brian Lehmann, David M. Terrian, Michele Milella, Agostino Tafuri, Franca Stivala, Massimo Libra, Jorg Basecke, Camilla Evangelisti, Alberto M. Martelli & Richard A. Franklin. (2007) Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773:8, pages 1263-1284.
Crossref
Crossref
Rajendra S. Singh, A. Hafeez Diwan, Peter S. Zhang & Victor G. Prieto. (2007) Phosphoinositide 3-kinase is not overexpressed in melanocytic lesions. Journal of Cutaneous Pathology 34:3, pages 220-225.
Crossref
Crossref
A.A. Mortlock & A.J. Barker. 2007. Comprehensive Medicinal Chemistry II. Comprehensive Medicinal Chemistry II
183
220
.
James A. McCubrey, Fred E. Bertrand, Linda S. Steelman, Fumin Chang, David M. Terrian & Richard A. Franklin. 2007. Apoptosis, Cell Signaling, and Human Diseases. Apoptosis, Cell Signaling, and Human Diseases
101
134
.
Satoshi AnaiSteve GoodisonKathleen ShiverickKenneth IczkowskiMotoyoshi TanakaCharles J. Rosser. (2006)
Combination of
PTEN
Gene Therapy and Radiation Inhibits the Growth of Human Prostate Cancer Xenografts
. Human Gene Therapy 17:10, pages 975-984.
Crossref
Crossref
Satoshi Anai, Steve Goodison, Kathleen Shiverick, Kenneth Iczkowski, Motoyoshi Tanaka & Charles J. Rosser. (2006)
Combination of
PTEN
Gene Therapy and Radiation Inhibits the Growth of Human Prostate Cancer Xenografts
. Human Gene Therapy 0:0, pages 060919113707002.
Crossref
Crossref
Maria Nyåkern, Alessandra Cappellini, Irina Mantovani & Alberto M. Martelli. (2006) Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways. Molecular Cancer Therapeutics 5:6, pages 1559-1570.
Crossref
Crossref
A M Martelli, M Nyåkern, G Tabellini, R Bortul, P L Tazzari, C Evangelisti & L Cocco. (2006) Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia. Leukemia 20:6, pages 911-928.
Crossref
Crossref
Carole Sourbier, Véronique Lindner, Hervé Lang, Abdelali Agouni, Eric Schordan, Sabrina Danilin, Sylvie Rothhut, Didier Jacqmin, Jean-Jacques Helwig & Thierry Massfelder. (2006) The Phosphoinositide 3-Kinase/Akt Pathway: A New Target in Human Renal Cell Carcinoma Therapy. Cancer Research 66:10, pages 5130-5142.
Crossref
Crossref
Shao-Ping Ji, Yun Zhang, Jamie Van Cleemput, Wen Jiang, Mingxia Liao, Lei Li, Qi Wan, Jon R Backstrom & Xia Zhang. (2006) Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. Nature Medicine 12:3, pages 324-329.
Crossref
Crossref
M Nyåkern, P L Tazzari, C Finelli, C Bosi, M Y Follo, T Grafone, P P Piccaluga, G Martinelli, L Cocco & A M Martelli. (2005) Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients. Leukemia 20:2, pages 230-238.
Crossref
Crossref
Y. Zhu, P. Hoell, B. Ahlemeyer & J. Krieglstein. (2006) PTEN: A crucial mediator of mitochondria-dependent apoptosis. Apoptosis 11:2, pages 197-207.
Crossref
Crossref
James A. McCubrey, Linda S. Steelman, Steven L. Abrams, John T. Lee, Fumin Chang, Fred E. Bertrand, Patrick M. Navolanic, David M. Terrian, Richard A. Franklin, Antonio B. D’Assoro, Jeffrey L. Salisbury, Maria Clorinda Mazzarino, Franca Stivala & Massimo Libra. (2006) Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance. Advances in Enzyme Regulation 46:1, pages 249-279.
Crossref
Crossref
Paul M. Campbell, Anurag Singh, Falina J. Williams, Karen Frantz, Aylin S. Ülfü, Grant G. Kelley & Channing J. Der. 2006. Regulators and Effectors of Small GTPases: Ras Family. Regulators and Effectors of Small GTPases: Ras Family
195
217
.
James J. Fiordalisi, Channing J. Der & Adrienne D. Cox. 2006. RAS Family GTPases. RAS Family GTPases
353
380
.