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Exploratory Safety Pharmacology: a new safety paradigm to de-risk drug candidates prior to selection for regulatory science investigations

, PhD
Pages 627-647 | Received 24 Aug 2009, Accepted 24 Sep 2009, Published online: 05 Nov 2009

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Icilio Cavero. (2013) 2012 Annual Meeting of the Safety Pharmacology Society: spotlight on targeted oncology medicines. Expert Opinion on Drug Safety 12:4, pages 589-603.
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Icilio Cavero. (2011) 10th annual meeting of the Safety Pharmacology Society: an overview. Expert Opinion on Drug Safety 10:2, pages 319-333.
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Icilio Cavero. (2010) Cardiovascular system assessment best practices: a Safety Pharmacology Society meeting. Expert Opinion on Drug Safety 9:5, pages 855-866.
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Icilio Cavero. (2010) Safety Pharmacology Society: 9th Annual Meeting. Expert Opinion on Drug Safety 9:2, pages 365-378.
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Varun Ahuja & Sharad Sharma. (2014) Drug safety testing paradigm, current progress and future challenges: an overview. Journal of Applied Toxicology 34:6, pages 576-594.
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Bernard Christophe. (2013) Simulation of early after-depolarisation in non-failing human ventricular myocytes: Can this help cardiac safety pharmacology?. Pharmacological Reports 65:5, pages 1281-1293.
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Theodore J. Baird, David V. Gauvin & Jill A. Dalton. 2013. A Comprehensive Guide to Toxicology in Preclinical Drug Development. A Comprehensive Guide to Toxicology in Preclinical Drug Development 107 140 .
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Bernard Testa, Alessandro Pedretti & Giulio Vistoli. (2012) Reactions and enzymes in the metabolism of drugs and other xenobiotics. Drug Discovery Today 17:11-12, pages 549-560.
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Zhi Su & Gary Gintant. 2011. Heart Rate and Rhythm. Heart Rate and Rhythm 627 638 .

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