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Voriconazole therapeutic drug monitoring: focus on safety

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Pages 125-137 | Published online: 20 Dec 2009

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Eliska Dvorackova, Martin Sima, Kristyna Vyskocilova, Tereza Kotowski, Kateřina Dunovská, Eva Klapkova, Jan Havlin, Robert Lischke & Ondrej Slanar. (2023) Population pharmacokinetics and covariate-based dosing individualization of voriconazole in lung transplant recipients. Journal of Chemotherapy 0:0, pages 1-10.
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Josefine Schulz, Franziska Kluwe, Gerd Mikus, Robin Michelet & Charlotte Kloft. (2019) Novel insights into the complex pharmacokinetics of voriconazole: a review of its metabolism. Drug Metabolism Reviews 51:3, pages 247-265.
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Gulsum Iclal Bayhan, Mesut Garipardic, Kamuran Karaman & Sinan Akbayram. (2016) Voriconazole-associated visual disturbances and hallucinations. Cutaneous and Ocular Toxicology 35:1, pages 80-82.
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Hemant Malhotra, Pratibha Sharma, Shipra Bhargava, Om Singh Rathore, Bharti Malhotra & Madhu Kumar. (2014) Correlation of plasma trough levels of imatinib with molecular response in patients with chronic myeloid leukemia. Leukemia & Lymphoma 55:11, pages 2614-2619.
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Mehwish Mushtaq, Kshaf Fatima, Aneeqa Ahmad, Osama Mohamed Ibrahim, Muhammad Faheem & Yasar Shah. (2023) Pharmacokinetic interaction of voriconazole and clarithromycin in Pakistani healthy male volunteers: a single dose, randomized, crossover, open-label study. Frontiers in Pharmacology 14.
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Laís de Almeida Campos, Margani Taise Fin, Kelvin Sousa Santos, Marcos William de Lima Gualque, Ana Karla Lima Freire Cabral, Najeh Maissar Khalil, Ana Marisa Fusco-Almeida, Rubiana Mara Mainardes & Maria José Soares Mendes-Giannini. (2023) Nanotechnology-Based Approaches for Voriconazole Delivery Applied to Invasive Fungal Infections. Pharmaceutics 15:1, pages 266.
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Nhi Nguyen, Hubert C. Chua, Ty Drake, Jinhee Jo, Stefanie Anne Stramel, Nancy N. Vuong, Anne J. Gonzales-Luna, Kelsey Olson & on behalf of the Houston Infectious Diseases Network. (2022) Significant Publications on Infectious Diseases Pharmacotherapy in 2021. Journal of Pharmacy Practice, pages 089719002211283.
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Juan Chen, Ying Wu, Yuelin He, Xiaoqin Feng, Yuqiong Ren & Shiting Liu. (2022) Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children. Frontiers in Pediatrics 10.
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Josefine Schulz, Antonia Thomas, Ayatallah Saleh, Gerd Mikus, Charlotte Kloft & Robin Michelet. (2022) Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism. Pharmaceutics 14:3, pages 477.
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Yaser Mohammed, Ahmed Abousamra, Ahmed Atef I Abdeldayem, Mansoor Zafar & Tila Muhammad. (2022) Voriconazole-Induced Cholestatic Hepatotoxicity in an Immune Competent Patient. Cureus.
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Johan A Maertens, Galia Rahav, Dong-Gun Lee, Alfredo Ponce-de-León, Isabel Cristina Ramírez Sánchez, Nikolay Klimko, Anne Sonet, Shariq Haider, Juan Diego Vélez, Issam Raad, Liang-Piu Koh, Meinolf Karthaus, Jianying Zhou, Ronen Ben-Ami, Mary R Motyl, Seongah Han, Anjana Grandhi & Hetty Waskin. (2021) Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial. The Lancet 397:10273, pages 499-509.
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Stephanie Duehlmeyer, Christopher Klockau, Diana Yu & Jamie Rouch. (2021) Characterization of Therapeutic Drug Monitoring Practices of Voriconazole and Posaconazole at a Pediatric Hospital. The Journal of Pediatric Pharmacology and Therapeutics 26:1, pages 26-32.
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Sarah Allegra, Silvia De Francia, Amedeo De Nicolò, Jessica Cusato, Valeria Avataneo, Alessandra Manca, Miriam Antonucci & Antonio D’Avolio. (2020) Effect of Gender and Age on Voriconazole Trough Concentrations in Italian Adult Patients. European Journal of Drug Metabolism and Pharmacokinetics 45:3, pages 405-412.
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Qi Huang, Qiong Liu, Tao Yin, Lin Hu, Hanjun Ding, Shao Liu & Yueping Jiang. (2020) Effect of proton pump inhibitors on voriconazole concentrations in Chinese patients with malignant hematological diseases. European Journal of Clinical Pharmacology 76:6, pages 833-842.
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Lin Cheng, Rongfeng Xiang, Fang Liu, Yuliang Li, Heli Chen, Pu Yao, Fengjun Sun & Peiyuan Xia. (2020) Therapeutic drug monitoring and safety of voriconazole in elderly patients. International Immunopharmacology 78, pages 106078.
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Syed Haris Tasleem & Mitchell S. Cappell. (2019) Voriconazole-Induced Hepatotoxicity Presenting With Severe Hepatic Encephalopathy After Liver Transplantation. ACG Case Reports Journal 6:3, pages e00010.
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Nikolaos Spernovasilis & Diamantis Kofteridis. (2018) Pre-Existing Liver Disease and Toxicity of Antifungals. Journal of Fungi 4:4, pages 133.
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Ignacio G. Bressán, Mariana L. Mendez & María I. Gimenez. (2018) Validation of a Reversed-Phase Ultra–High-Performance Liquid Chromatographic Method With Photodiode Array Detection for the Determination of Voriconazole in Human Serum and Its Application to Therapeutic Drug Monitoring. Therapeutic Drug Monitoring 40:2, pages 276-283.
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Zahra Hashemizadeh, Parisa Badiee, Seyed Ali Malekhoseini, Hadi Raeisi Shahraki, Bita Geramizadeh & Hashem Montaseri. (2017) Observational Study of Associations between Voriconazole Therapeutic Drug Monitoring, Toxicity, and Outcome in Liver Transplant Patients. Antimicrobial Agents and Chemotherapy 61:12.
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Xiaoyan Liu, Haibin Su, Jingjing Tong, Jing Chen, Haozhen Yang, Long Xiao, Jinhua Hu & Lina zhang. (2017) Significance of monitoring plasma concentration of voriconazole in a patient with liver failure. Medicine 96:42, pages e8039.
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Omar Abdulhameed Almazroo, Mohammad Kowser Miah & Raman Venkataramanan. (2017) Drug Metabolism in the Liver. Clinics in Liver Disease 21:1, pages 1-20.
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Prerna K. Chawla, Alpa J. Dherai & Tester F. Ashavaid. (2015) Plasma Voriconazole Estimation by HPLC. Indian Journal of Clinical Biochemistry 31:2, pages 209-214.
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H.R. Ashbee & M.H. Gilleece. 2014. Handbook of Pharmacogenomics and Stratified Medicine. Handbook of Pharmacogenomics and Stratified Medicine 879 900 .
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Daniela Silva Granzoto, Lúcia Helena Vitali & Roberto Martinez. (2013) Efficacy of voriconazole in experimental rat paracoccidioidomycosis. Revista da Sociedade Brasileira de Medicina Tropical 46:1, pages 79-83.
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Si-Hyun KimDong-Gun LeeJae-Cheol KwonHyo-Jin LeeSung-Yeon ChoChulmin ParkEun-Young KwonSun Hee ParkSu-Mi ChoiJung-Hyun ChoiJin-Hong Yoo. (2013) Clinical Impact of Cytochrome P450 2C19 Genotype on the Treatment of Invasive Aspergillosis under Routine Therapeutic Drug Monitoring of Voriconazole in a Korean Population. Infection & Chemotherapy 45:4, pages 406.
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Thomas N. Kakuda, Rodica Van Solingen‐Ristea, Fatima Aharchi, Goedele De Smedt, James Witek, Steven Nijs, Veerle Vyncke & Richard M. W. Hoetelmans. (2013) Pharmacokinetics and Short‐Term Safety of Etravirine in Combination With Fluconazole or Voriconazole in HIV‐Negative Volunteers. The Journal of Clinical Pharmacology 53:1, pages 41-50.
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Soo‐Han Choi, Soo‐Youn Lee, Ji‐Young Hwang, Soo Hyun Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo & Yae‐Jean Kim. (2012) Importance of voriconazole therapeutic drug monitoring in pediatric cancer patients with invasive aspergillosis. Pediatric Blood & Cancer 60:1, pages 82-87.
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