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Drug Safety Evaluations

Mirabegron: a safety review

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Pages 287-294 | Published online: 09 Dec 2010

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Hadi Mostafaei, Shahrokh F. Shariat, Hanieh Salehi-Pourmehr, Florian Janisch, Keiichiro Mori, Fahad Quhal & Sakineh Hajebrahimi. (2020) The clinical pharmacology of the medical treatment for overactive bladder in adults. Expert Review of Clinical Pharmacology 13:7, pages 707-720.
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David Mobley, Allison Feibus & Neil Baum. (2015) Benign prostatic hyperplasia and urinary symptoms: Evaluation and treatment. Postgraduate Medicine 127:3, pages 301-307.
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Mahendra Kashyap & Pradeep Tyagi. (2013) The pharmacokinetic evaluation of mirabegron as an overactive bladder therapy option. Expert Opinion on Drug Metabolism & Toxicology 9:5, pages 617-627.
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Articles from other publishers (32)

Anirban Ganguly, Shachi Tyagi, Christopher Chermansky, Anthony Kanai, Jonathan Beckel, Mamoru Hashimoto, Kang Jun Cho, Michael Chancellor, Jonathan Kaufman, Naoki Yoshimura & Pradeep Tyagi. (2023) Treating Lower Urinary Tract Symptoms in Older Adults: Intravesical Options. Drugs & Aging 40:3, pages 241-261.
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Tanja Hüsch, André Reitz, Laila Schneidewind & Jennifer Kranz. (2021) 32/w mit irritativen Miktionsbeschwerden32/f with lower urinary tract symptoms. Der Urologe 61:S2, pages 56-62.
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Kritika Laxmikeshav, Pooja Kumari & Nagula Shankaraiah. (2021) Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update. Medicinal Research Reviews 42:1, pages 513-575.
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Pankaj Mandpe, Bala Prabhakar & Pravin Shende. (2019) 23 Full factorial design for optimization of stable amorphous host–guest-based mirabegron complex for extended-release action. Journal of Inclusion Phenomena and Macrocyclic Chemistry 96:1-2, pages 111-123.
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Andrzej Wróbel, Barbara Miziak, Małgorzata Bańczerowska‐Górska, Aleksandra Szopa, Anna Serefko, Klaudia Stangel‐Wójcikiewicz, Piotr Czuczwar, Marzena Laskowska, Edyta Wlaźlak, Jarosław Dudka & Ewa Poleszak. (2019) The influence of nebivolol on the activity of BRL 37344 — the β3‐adrenergic receptor agonist, in the animal model of detrusor overactivity. Neurourology and Urodynamics 38:5, pages 1229-1240.
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Blayne Welk, Duane Hickling, Mary McKibbon, Sidney Radomski & Karen Ethans. (2018) A pilot randomized-controlled trial of the urodynamic efficacy of mirabegron for patients with neurogenic lower urinary tract dysfunction. Neurourology and Urodynamics 37:8, pages 2810-2817.
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Renee D. Schmid & Lynn R. Hovda. (2017) Mirabegron Toxicosis in Dogs: a Retrospective Study. Journal of Medical Toxicology 14:2, pages 160-167.
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Larry Yet. 2018. Privileged Structures in Drug Discovery. Privileged Structures in Drug Discovery 284 320 .
Yasuhiro Wada, Seiji Nakano, Akifumi Morimoto, Ken-ichi Kasahara, Takahiko Hayashi, Yoshio Takada, Hiroko Suzuki, Michiko Niwa-Sakai, Shigeki Ohashi, Mutsuhiro Mori, Takatsugu Hirokawa & Satoshi Shuto. (2017) Discovery of Novel Indazole Derivatives as Orally Available β 3 -Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects . Journal of Medicinal Chemistry 60:8, pages 3252-3265.
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Henning Bundgaard, Anna Axelsson, Jakob Hartvig Thomsen, Mathias Sørgaard, Klaus F. Kofoed, Rasmus Hasselbalch, Natasha A.S. Fry, Nana Valeur, Søren Boesgaard, Finn Gustafsson, Lars Køber, Kasper Iversen & Helge H. Rasmussen. (2017) The first-in-man randomized trial of a beta3 adrenoceptor agonist in chronic heart failure: the BEAT-HF trial. European Journal of Heart Failure 19:4, pages 566-575.
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S.D. Edmondson. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 714 737 .
Ryuji Sakakibara, Jalesh Panicker, Enrico Finazzi-Agro, Valerio Iacovelli & Homero Bruschini. (2016) A guideline for the management of bladder dysfunction in Parkinson's disease and other gait disorders. Neurourology and Urodynamics 35:5, pages 551-563.
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Yasuhiro Wada, Hiromitsu Shirahashi, Taisuke Iwanami, Masami Ogawa, Seiji Nakano, Akifumi Morimoto, Ken-ichi Kasahara, Eiichi Tanaka, Yoshio Takada, Shigeki Ohashi, Mutsuhiro Mori & Satoshi Shuto. (2015) Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β 3 -Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects . Journal of Medicinal Chemistry 58:15, pages 6048-6057.
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Fuyuki Tateno, Ryuji Sakakibara, Tsuyoshi Ogata, Masahiko Kishi, Yohei Tsuyusaki, Osamu Takahashi, Megumi Sugiyama & Akihiko Tateno. (2014) Lower urinary tract function in dementia with Lewy bodies (DLB). Movement Disorders 30:3, pages 411-415.
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Pradipbhai D. Kalariya, Mahesh Sharma, Prabha Garg, Jagadeshwar Reddy Thota, Srinivas Ragampeta & M. V. N. Kumar Talluri. (2015) Characterization of stress degradation products of mirabegron using UPLC-QTOF-MS/MS and in silico toxicity predictions of its degradation products. RSC Advances 5:39, pages 31024-31038.
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Ryuji Sakakibara. 2015. Neurology of Sexual and Bladder Disorders. Neurology of Sexual and Bladder Disorders 269 287 .
Lucio M.A. Cipullo, Cosimo Cosimato, Amelia Filippelli, Valeria Conti, Viviana Izzo, Fulvio Zullo & Maurizio Guida. (2014) Pharmacological approach to overactive bladder and urge urinary incontinence in women: an overview. European Journal of Obstetrics & Gynecology and Reproductive Biology 174, pages 27-34.
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Tao Wu, Xi Duan, Chen-Xi Cao, Chuan-Du Peng, Si-Yuan Bu & Kun-Jie Wang. (2014) The Role of Mirabegron in Overactive Bladder: A Systematic Review and Meta-Analysis. Urologia Internationalis 93:3, pages 326-337.
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Ryuji Sakakibara, Jalesh Panicker, Clare J Fowler, Fuyuki Tateno, Masahiko Kishi, Yohei Tsuyusaki, Tomonori Yamanishi, Tomoyuki Uchiyama, Tatsuya Yamamoto & Masashi Yano. (2014) Is overactive bladder a brain disease? The pathophysiological role of cerebral white matter in the elderly. International Journal of Urology 21:1, pages 33-38.
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Jamie M. Bartley, Emily S. Blum, Larry T. Sirls & Kenneth M. Peters. (2013) Understanding Clinic Options for Overactive Bladder. Current Urology Reports 14:6, pages 541-548.
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Victor W. Nitti, Steven Rosenberg, David H. Mitcheson, Weizhong He, Allam Fakhoury & Nancy E. Martin. (2013) Urodynamics and Safety of the β 3 -Adrenoceptor Agonist Mirabegron in Males with Lower Urinary Tract Symptoms and Bladder Outlet Obstruction . Journal of Urology 190:4, pages 1320-1327.
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Ryuji SAKAKIBARA, Takashi ITO, Tatsuya YAMAMOTO, Tomoyuki UCHIYAMA, Tomonori YAMANISHI, Masahiko KISHI, Yohei TSUYUSAKI, Fuyuki TATENO, Shuichi KATSURAGAWA & Nobuo KUROKI. (2013) Depression, Anxiety and the Bladder. LUTS: Lower Urinary Tract Symptoms 5:3, pages 109-120.
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Gary D. NovackRichard A. LewisRoger VogelNeha ShethDennis SwearingenScott RasmussenGary HantsbargerNancy E. Martin. (2013) Randomized, Double-Masked, Placebo-Controlled Study to Assess the Ocular Safety of Mirabegron in Healthy Volunteers. Journal of Ocular Pharmacology and Therapeutics 29:7, pages 674-680.
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. (2013) ▼Mirabegron for overactive bladder syndrome:. Drug and Therapeutics Bulletin 51:8, pages 90-92.
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Hong X. Ding, Kevin K.-C. Liu, Subas M. Sakya, Andrew C. Flick & Christopher J. O’Donnell. (2013) Synthetic approaches to the 2011 new drugs. Bioorganic & Medicinal Chemistry 21:11, pages 2795-2825.
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Joy A. Greer, Lily A. Arya & Ariana L. Smith. (2013) Urinary Incontinence: Diagnosis and Treatment in the Elderly. Current Translational Geriatrics and Experimental Gerontology Reports 2:2, pages 66-75.
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Adrian Wagg. (2012) Fesoterodine fumarate for the treatment of overactive bladder in the elderly – a review of the latest clinical data. Clinical Investigation 2:8, pages 825-833.
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Jack Humphrey. (2012) How Drugs Modify The Micturition Reflex: A Review. Opticon1826 7:12, pages 9.
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Sayoko Kanie, Atsushi Otsuka, Satoru Yoshikawa, Takashi Morimoto, Nana Hareyama, Seiji Okazaki, Ryosuke Kobayashi, Ko Hasebe, Kaoru Nakao, Ryoji Hayashi, Hidenori Mochizuki, Rikiya Matsumoto & Seiichiro Ozono. (2012) Pharmacological Effect of TRK-380, a Novel Selective Human β3-Adrenoceptor Agonist, on Mammalian Detrusor Strips. Urology 79:3, pages 744.e1-744.e7.
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Altaf Mangera & Christopher R. Chapple. (2011) Summary of Anticholinergic Pharmacotherapy Available for Overactive Bladder Dysfunction. Current Bladder Dysfunction Reports 7:1, pages 51-58.
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Anthony Kanai, Irina Zabbarova, Michael Oefelein, Piotr Radziszewski, Youko Ikeda & Karl‐Erik Andersson. (2012) Mechanisms of action of botulinum neurotoxins, β 3 ‐adrenergic receptor agonists, and PDE5 inhibitors in modulating detrusor function in overactive bladders: ICI‐RS 2011 . Neurourology and Urodynamics 31:3, pages 300-308.
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Fotios Dimitriadis, Motoaki Saito, Fumiya Ohmasa, Seiya Inoue & Keisuke Satoh. (2011) A β3 Agonist, Mirabegron for the Treatment of Overactive Bladder. UroToday International Journal 04:06.
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