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Expert Opinion on Drug Safety Volume 10, 2011 - Issue 4

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Safety and efficacy of treatment for chronic hepatitis C with a focus on pegylated interferons: the backbone of therapy today and in the future

Peter Ferenci Medical University of Vienna, Univ. Klinik für Innere Medizin III, Währinger Gürtel 18-20, A 1090 Vienna, Austria+43 1 40400 4741; +43 1 40400 4735; [email protected]

, MD

Pages 529-544 | Published online: 23 Feb 2011

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https://doi.org/10.1517/14740338.2011.555079

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Lai Wei, Fu-Sheng Wang, Ming-Xiang Zhang, Ji-Dong Jia, Alexey A Yakovlev, Wen Xie, Eduard Burnevich, Jun-Qi Niu, Yong Jin Jung, Xiang-Jun Jiang, Min Xu, Xin-Yue Chen, Qing Xie, Jun Li, Jin-Lin Hou, Hong Tang, Xiao-Guang Dou, Yash Gandhi, Wen-Hua Hu, Fiona Mcphee, Stephanie Noviello, Michelle Treitel, Ling Mo & Jun Deng. (2018) Daclatasvir plus asunaprevir in treatment-naïve patients with hepatitis C virus genotype 1b infection. World Journal of Gastroenterology 24:12, pages 1361-1372.
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Harry L.A. Janssen, Maurizia R. Brunetto, Yoon Jun Kim, Carlo Ferrari, Benedetta Massetto, Anh-Hoa Nguyen, Adarsh Joshi, Jacky Woo, Audrey H. Lau, Anuj Gaggar, G. Mani Subramanian, Eric M. Yoshida, Sang Hoon Ahn, Naoky C.S. Tsai, Scott Fung & Edward J. Gane. (2018) Safety, efficacy and pharmacodynamics of vesatolimod (GS-9620) in virally suppressed patients with chronic hepatitis B. Journal of Hepatology 68:3, pages 431-440.
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Eric Lawitz, Daniel Gruener, Thomas Marbury, John Hill, Lynn Webster, David Hassman, Anh-Hoa Nguyen, Stefan Pflanz, Erik Mogalian, Anuj Gaggar, Benedetta Massetto, G Mani Subramanian, John G McHutchison, Ira M Jacobson, Bradley Freilich & Maribel Rodriguez-Torres. (2014) Safety, Pharmacokinetics and Pharmacodynamics of the Oral Toll-Like Receptor 7 Agonist GS-9620 in Treatment-Naive Patients with Chronic Hepatitis C. Antiviral Therapy 20:7, pages 699-708.
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Peter Ferenci. (2015) Treatment of hepatitis C in difficult-to-treat patients. Nature Reviews Gastroenterology & Hepatology 12:5, pages 284-292.
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K. Rutter, A. F. Stättermayer, S. Beinhardt, T.-M. Scherzer, P. Steindl-Munda, M. Trauner, P. Ferenci & H. Hofer. (2015) Successful anti-viral treatment improves survival of patients with advanced liver disease due to chronic hepatitis C. Alimentary Pharmacology & Therapeutics 41:6, pages 521-531.
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M. Rizzetto, K. Grotzinger, D. Theodore, D. Demuth, W. L. Irving, M. Manns, A. Roughley & U. M. Forssen. (2014) Reasons for nonuse of antiviral treatment in patients with chronic hepatitis C infection and thrombocytopaenia: a retrospective chart review from five European countries. Journal of Viral Hepatitis 21:10, pages e129-e134.
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Eric Lawitz, Maribel Rodriguez-Torres, Jill M. Denning, Efsevia Albanis, Melanie Cornpropst, Michelle M. Berrey & William T. Symonds. (2013) Pharmacokinetics, Pharmacodynamics, and Tolerability of GS-9851, a Nucleotide Analog Polymerase Inhibitor, following Multiple Ascending Doses in Patients with Chronic Hepatitis C Infection. Antimicrobial Agents and Chemotherapy 57:3, pages 1209-1217.
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Julia Rempel & Julia Uhanova. (2012) Hepatitis C Virus in American Indian/Alaskan Native and Aboriginal Peoples of North America. Viruses 4:12, pages 3912-3931.
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Edoardo G. Giannini, Simona Marenco, Valentina Fazio, Giulia Pieri, Vincenzo Savarino & Antonino Picciotto. (2012) Peripheral blood cytopaenia limiting initiation of treatment in chronic hepatitis C patients otherwise eligible for antiviral therapy. Liver International 32:7, pages 1113-1119.
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B.A. Payer, T. Reiberger, F. Breitenecker, M.C. Aichelburg, C. Schuster, P.M. Heil, T.M. Scherzer, P. Ferenci, A. Rieger & M. Peck-Radosavljevic. (2012) The risk of infections in HIV-HCV coinfected patients during antiviral therapy with pegIFN+RBV. Journal of Infection 65:2, pages 142-149.
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Stela Vujosevic, Diego Tempesta, Franco Noventa, Edoardo Midena & Giada Sebastiani. (2012) Pegylated interferon-associated retinopathy is frequent in hepatitis C virus patients with hypertension and justifies ophthalmologic screening. Hepatology 56:2, pages 455-463.
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Milena Fioravante, Sarah Monte Alegre, Daniela Miguel Marin, Sonia Leticia Silva Lorena, Tiago Sevá Pereira & Elza Cotrim Soares. (2012) Weight loss and resting energy expenditure in patients with chronic hepatitis C before and during standard treatment. Nutrition 28:6, pages 630-634.
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Ruth Duncan. (2011) Polymer therapeutics as nanomedicines: new perspectives. Current Opinion in Biotechnology 22:4, pages 492-501.
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Safety and efficacy of treatment for chronic hepatitis C with a focus on pegylated interferons: the backbone of therapy today and in the future

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Safety and efficacy of treatment for chronic hepatitis C with a focus on pegylated interferons: the backbone of therapy today and in the future

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