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Expert Opinion on Drug Safety Volume 12, 2013 - Issue 6
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Reviews

Safety profile of two novel antiepileptic agents approved for the treatment of refractory partial seizures: ezogabine (retigabine) and perampanel

Michele A FaulknerCreighton University School of Pharmacy and Health Professions and School of Medicine, 2500 California Plaza, Omaha, NE, 68178, USA+1 402 280 3145; [email protected]
, PharmD &
Rachel A BurkeCreighton University School of Pharmacy and Health Professions, Omaha, NE, USA
, PharmD
Pages 847-855 | Published online: 25 Jul 2013

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Andreas Schulze-Bonhage & Mandy Hintz. (2015) Perampanel in the management of partial-onset seizures: a review of safety, efficacy, and patient acceptability. Patient Preference and Adherence 9, pages 1143-1151.
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Articles from other publishers (20)

Gülnar Farmanlı, Sinem Ilgın, Bülent Ergun, Merve Baysal, Abdullah Burak Karaduman & Özlem Atlı Eklioğlu. (2023) Evaluation of in vitro hepatotoxicity of perampanel in comparison with carbamazepine: old versus new. European Journal of Life Sciences 2:2, pages 59-70.
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Tingting Hu, Jifa Zhang, Jiaxing Wang, Leihao Sha, Yilin Xia, Tyler C. Ortyl, Xiaohe Tian & Lei Chen. (2023) Advances in Epilepsy: Mechanisms, Clinical Trials, and Drug Therapies. Journal of Medicinal Chemistry 66:7, pages 4434-4467.
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Mark Estacion, Shujun Liu, Xiaoyang Cheng, Sulayman Dib-Hajj & Stephen G. Waxman. (2023) Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability. Frontiers in Pharmacology 14.
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Favin S. Babu & Matthias Majetschak. (2021) Linopirdine-supplemented resuscitation fluids reduce mortality in a model of ischemia-reperfusion injury induced acute respiratory distress syndrome. Physiological Research 70:4, pages 649-653.
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Yang D. Teng & Ross D. Zafonte. (2021) Prelude to the special issue on novel neurocircuit, cellular and molecular targets for developing functional rehabilitation therapies of neurotrauma. Experimental Neurology 341, pages 113689.
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Tian Li, Kun Wu, Zhenlei Yue, Yifei Wang, Fan Zhang & Huaizong Shen. (2021) Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs. Molecular Cell 81:1, pages 25-37.e4.
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Lai, Tzeng, Huang & Wu. (2019) The Novel Direct Modulatory Effects of Perampanel, an Antagonist of AMPA Receptors, on Voltage-Gated Sodium and M-type Potassium Currents. Biomolecules 9:10, pages 638.
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Bradley K. Taylor, Ghanshyam P. Sinha, Renee R. Donahue, Carolyn M. Grachen, Jose A. Morón & Suzanne Doolen. (2019) Opioid receptors inhibit the spinal AMPA receptor Ca2+ permeability that mediates latent pain sensitization. Experimental Neurology 314, pages 58-66.
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Takuji Nishida, Sang Kun Lee, Tony Wu, Somsak Tiamkao & Amitabh Dash. (2019) Efficacy and safety of perampanel in generalized and focal to bilateral tonic‐clonic seizures: A comparative study of Asian and non‐Asian populations. Epilepsia 60:S1, pages 47-59.
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Filippo Ghezzi, Laura Monni & Andrea Nistri. (2018) Functional up‐regulation of the M‐current by retigabine contrasts hyperexcitability and excitotoxicity on rat hypoglossal motoneurons. The Journal of Physiology 596:13, pages 2611-2629.
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Marco de Curtis, Laura Uva, Vadym Gnatkovsky & Laura Librizzi. (2018) Potassium dynamics and seizures: Why is potassium ictogenic?. Epilepsy Research 143, pages 50-59.
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Valentina Franco, Katia Baruffi, Giuliana Gatti, Roberto Marchiselli, Cinzia Fattore, Maria Paola Canevini, Francesca Crema & Emilio Perucca. (2018) A simple and rapid HPLC‐UV method for the determination of retigabine in human plasma. Biomedical Chromatography 32:5.
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Christoph BörgersR. Melody TakeuchiDaniel T. Rosebrock. (2018) On Rhythms in Neuronal Networks with Recurrent Excitation. Neural Computation 30:2, pages 333-377.
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Sean P. Nassoiy, Kenneth L. Byron & Matthias Majetschak. (2017) Kv7 voltage-activated potassium channel inhibitors reduce fluid resuscitation requirements after hemorrhagic shock in rats. Journal of Biomedical Science 24:1.
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Dennis Dlugos, Greg Worrell, Kathryn Davis, William Stacey, Jerzy Szaflarski, Andres Kanner, Sridhar Sunderam, Mike Rogawski, Patrice Jackson-Ayotunde, Tobias Loddenkemper, Beate Diehl, Brandy Fureman & Ray Dingledine. (2016) 2014 Epilepsy Benchmarks Area III: Improve Treatment Options for Controlling Seizures and Epilepsy-Related Conditions without Side Effects. Epilepsy Currents 16:3, pages 192-197.
Crossref
Hana Kubova. 2016. Antiepileptic Drug Discovery. Antiepileptic Drug Discovery 329 350 .
Eylert Brodtkorb. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy 193 204 .
Jakob Wolfart & Debora Laker. (2015) Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential. Frontiers in Physiology 6.
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P. Zhou, Y. Zhang, H. Xu, F. Chen, X. Chen, X. Li, X. Pi, L. Wang, L. Zhan, F. Nan & Z. Gao. (2014) P-Retigabine: An N-Propargyled Retigabine with Improved Brain Distribution and Enhanced Antiepileptic Activity. Molecular Pharmacology 87:1, pages 31-38.
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Elinor Ben‐Menachem. (2014) Medical management of refractory epilepsy—Practical treatment with novel antiepileptic drugs. Epilepsia 55:s1, pages 3-8.
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