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Expert Opinion on Drug Safety Volume 13, 2014 - Issue 10
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Original Research

Safety and efficacy of various concentrations of topical lidocaine gel for intravitreal injection

Helio Francisco ShiromaFederal University of São Paulo, Department of Ophthalmology, William Richard Schisler 900, Florianopolis, 88034-100, [email protected];Federal University of São Paulo, Department of Ophthalmology, Rua Botucatu 821 - Vila Clementino 04023-062 - São Paulo, Brazil
, MD,
Eduardo Buchelle RodriguesFederal University of São Paulo, Department of Ophthalmology, Rua Botucatu 821 - Vila Clementino 04023-062 - São Paulo, Brazil
,
Michel E FarahFederal University of São Paulo, Department of Ophthalmology, Rua Botucatu 821 - Vila Clementino 04023-062 - São Paulo, Brazil
,
Fernando M PenhaFederal University of São Paulo, Department of Ophthalmology, Thomé Braga, 255 Apt 701, Blumenau, 89010-570, Brazil
, MD PhD,
Jose Carlos LorenzoFederal University of São Paulo, Department of Ophthalmology, Rua Botucatu 821 - Vila Clementino 04023-062 - São Paulo, Brazil
,
Astor GrumannFederal University of São Paulo, Department of Ophthalmology, Rua Botucatu 821 - Vila Clementino 04023-062 - São Paulo, Brazil
&
Renata Portella NunesFederal University of São Paulo, Department of Ophthalmology, Rua Presidente Coutinho 579/501, Florianopolis, 88015, Brazil
 show all
Pages 1299-1303 | Published online: 29 Aug 2014

Citations (18)

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Read on this site (4)

Priya R Chandrasekaran, Aamir A Aziz, Hannah Khan & Arshad M Khanani. (2023) Cooling Anesthesia for Intravitreal Injections – A Review. Clinical Ophthalmology 17, pages 197-207.
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Daniel L Chao, Nicolas T Rinella, Arshad M Khanani, Charles C Wykoff & Gun-Ho Kim. (2021) Cooling Anesthesia for Intravitreal Injection: Results of the Prospective Open-Label, Dose-Ranging COOL-1 Trial. Clinical Ophthalmology 15, pages 4659-4666.
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Jonathan Han, Nicholas T Rinella & Daniel L Chao. (2020) Anesthesia for Intravitreal Injection: A Systematic Review. Clinical Ophthalmology 14, pages 543-550.
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Aditi Gupta, Jennifer K. Sun & Paolo S. Silva. (2018) Complications of Intravitreous Injections in Patients with Diabetes. Seminars in Ophthalmology 33:1, pages 42-50.
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Articles from other publishers (14)

Xiubin MaQianqian LiangShuyue XueQi RenQing DuZhichun ZhangXinying LiXin LiuYan GaoJun Li. (2023) EFFECT OF ANESTHESIA DURATION ON INTRAVITREAL INJECTION PAIN. Retina 43:8, pages 1386-1392.
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Tong LinChangming Feng, Yanlong BiPeirong LuMingxing WuJia QuLan GongXinghuai Sun. (2022) Lidocaine Hydrochloride Gel for Ocular Surface Anesthesia: Pharmacokinetic Evaluation and Randomized Placebo-Controlled Trial in China. Journal of Ocular Pharmacology and Therapeutics 38:8, pages 567-575.
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Zhenkun Dong, Xutong Qu, Lu Zhang, Xueting Chen, Yuhang Dong, Hui Chen & Yan Cui. (2022) Efficacy and Safety of Oxybuprocaine Hydrochloride Gel in Alleviating Pain during Male Urethral Catheterization: A Single-Center Randomized Controlled Study. International Journal of Clinical Practice 2022, pages 1-5.
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Gustavo Barreto Melo, Natasha Ferreira Santos da Cruz, Geoffrey Guy Emerson, Flávio Atanázio Rezende, Carsten H. Meyer, Susumu Uchiyama, John Carpenter, Hélio Francisco Shiroma, Michel Eid Farah, Maurício Maia & Eduardo Büchele Rodrigues. (2021) Critical analysis of techniques and materials used in devices, syringes, and needles used for intravitreal injections. Progress in Retinal and Eye Research 80, pages 100862.
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Christoph Ehlken, Focke Ziemssen, Nicole Eter, Ines Lanzl, Hakan Kaymak, Albrecht Lommatzsch & Alexander K. Schuster. (2020) Systematic review: non-adherence and non-persistence in intravitreal treatment. Graefe's Archive for Clinical and Experimental Ophthalmology 258:10, pages 2077-2090.
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Patrícia Mazureki Campos, Raquel Petrilli & Renata F.V. Lopez. (2020) The prominence of the dosage form design to treat ocular diseases. International Journal of Pharmaceutics 586, pages 119577.
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Marie‐Claire Robin, Aurélie Papin, Alain Regnier & Jean-Yves Douet. (2020) Corneal anesthesia associated with topical application of 2% lidocaine nonophthalmic gel to healthy canine eyes. Veterinary Ophthalmology 23:3, pages 560-566.
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Helio Shiroma, Ana Luisa Höfling-Lima & Michel E. Farah. (2019) RE: Stem MS, et al: Predictors of Endophthalmitis after Intravitreal Injection: A multivariable analysis based on injection protocol and povidone iodine strength (Ophthalmol Retina. 2019;3:3-7). Ophthalmology Retina 3:8, pages e7.
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Saeed Karimi, Seyed Aliasghar Mosavi, Khosrow Jadidi, Homayoun Nikkhah & Bahareh Kheiri. (2018) Which quadrant is less painful for intravitreal injection? A prospective study. Eye 33:2, pages 304-312.
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Felipe Pereira, Hélio Francisco Shiroma, Muller Gonçalves Urias, Verônica Haysa Yamada, Acácio Alves de Souza Lima, Ana Luisa Hofling-Lima, Michel Eid Farah & Eduardo Buchele Rodrigues. (2017) Pilot Study Comparing Topical Anesthetic Agents in Pterygium Surgery: Subconjunctival Injection Versus 2% Lidocaine Gel Versus 5% Lidocaine Gel. Cornea 37:2, pages 194-198.
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Helio Francisco Shiroma, Augusto Key Karazawa Takaschima, Michel Eid Farah, Ana Luisa Höfling-Lima, Graziela de Luca Canto, Roberto Henrique Benedetti & Eduardo Buchele Rodrigues. (2017) Patient pain during intravitreal injections under topical anesthesia: a systematic review. International Journal of Retina and Vitreous 3:1.
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Munish SharmaRudra BhowmickHeather Gappa-Fahlenkamp. (2016) Drug-Loaded Nanoparticles Embedded in a Biomembrane Provide a Dual-Release Mechanism for Drug Delivery to the Eye. Journal of Ocular Pharmacology and Therapeutics 32:9, pages 565-573.
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Feng Zhang, Haiou Xia, Xia Li, Ling Qin, Hongmei Gu, Xujuan Xu & Meiyun Shen. (2016) Intraoral Vacuum of Breast-Feeding Newborns Within the First 24 Hr. Biological Research For Nursing 18:4, pages 445-453.
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Hélio Francisco ShiromaKleber Eidi ShimonoMichel Eid FarahRaquel GoldhardtAstor GrumannJr.Jr. & Eduardo Buchele Rodrigues. (2016) Comparative Study Between Lidocaine Gel 2% and 5% for Ophthalmic Procedures. Journal of Ocular Pharmacology and Therapeutics 32:4, pages 192-195.
Crossref

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