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Expert Opinion on Drug Safety Volume 3, 2004 - Issue 2
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Review

The effect of fibrates and other lipid-lowering drugs on plasma homocysteine levels

Jutta Dierkes Institute of Clinical Chemistry and Biochemistry, University Hospital Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. [email protected]
,
Sabine Westphal Institute of Clinical Chemistry and Biochemistry, University Hospital Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. [email protected]
&
Claus Luley Institute of Clinical Chemistry and Biochemistry, University Hospital Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. [email protected]
Pages 101-111 | Published online: 03 Mar 2005

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Robert S Rosenson. (2008) Fenofibrate: treatment of hyperlipidemia and beyond. Expert Review of Cardiovascular Therapy 6:10, pages 1319-1330.
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Yaqin Wei, Sergio Giunta & Shijin Xia. (2022) Hypoxia in Aging and Aging-Related Diseases: Mechanism and Therapeutic Strategies. International Journal of Molecular Sciences 23:15, pages 8165.
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Milan Holeček & Melita Vodeničarovová. (2020) Effects of low and high doses of fenofibrate on protein, amino acid, and energy metabolism in rat. International Journal of Experimental Pathology 101:5, pages 171-182.
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Cindy Yeoh, Howard Teng, Jacob Jackson, Lee Hingula, Takeshi Irie, Aron Legler, Corrine Levine, Iris Chu, Casey Chai & Luis Tollinche. (2019) Metabolic Disorders and Anesthesia. Current Anesthesiology Reports 9:3, pages 340-359.
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. (2016) Impact of Glycated Hemoglobin Level on Severity of Coronary Artery Disease in Non-Diabetic Patients. Journal of Cardiology & Current Research 7:4.
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Larry B. Goldstein & Judith H. Lichtman. 2013. Vascular Medicine: A Companion to Braunwald's Heart Disease. Vascular Medicine: A Companion to Braunwald's Heart Disease 349 360 .
Angelo Zinellu, Salvatore Sotgia, Giacomina Loriga, Luca Deiana, Andrea Ercole Satta & Ciriaco Carru. (2012) Oxidative stress improvement is associated with increased levels of taurine in CKD patients undergoing lipid-lowering therapy. Amino Acids 43:4, pages 1499-1507.
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Angelo Zinellu, Salvatore Sotgia, Elisabetta Pisanu, Giacomina Loriga, Luca Deiana, Andrea Ercole Satta & Ciriaco Carru. (2012) LDL S-homocysteinylation decrease in chronic kidney disease patients undergone lipid lowering therapy. European Journal of Pharmaceutical Sciences 47:1, pages 117-123.
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Theodosios D. Filippatos. (2012) A Review of Time Courses and Predictors of Lipid Changes with Fenofibric Acid-Statin Combination. Cardiovascular Drugs and Therapy 26:3, pages 245-255.
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David Sullivan, Peta Forder, John Simes, Malcolm Whiting, Leonard Kritharides, Alistair Merrifield, Mark Donoghoe, Peter G. Colman, Neil Graham, Hannu Haapamäki & Anthony Keech. (2011) Associations between the use of metformin, sulphonylureas, or diet alone and cardiovascular outcomes in 6005 people with type 2 diabetes in the FIELD study. Diabetes Research and Clinical Practice 94:2, pages 284-290.
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Dina M Schreinemachers. (2010) Perturbation of lipids and glucose metabolism associated with previous 2,4-D exposure: a cross-sectional study of NHANES III data, 1988-1994. Environmental Health 9:1.
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M. John Chapman, Jan S. Redfern, Mark E. McGovern & Philippe Giral. (2010) Niacin and fibrates in atherogenic dyslipidemia: Pharmacotherapy to reduce cardiovascular risk. Pharmacology & Therapeutics 126:3, pages 314-345.
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Michael H. Davidson. (2009) A Clinical Puzzle: Fibrates and Homocysteine Elevation. Cardiovascular Drugs and Therapy 23:5, pages 341-342.
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Monika Riederer, Wolfgang Erwa, Robert Zimmermann, Saša Frank & Rudolf Zechner. (2009) Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. Atherosclerosis 204:2, pages 412-417.
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Alberto J. Espay. 2009. Clinical Neurotoxicology. Clinical Neurotoxicology 115 130 .
Jean-Charles Fruchart, Frank Sacks, Michel P. Hermans, Gerd Assmann, W. Virgil Brown, Richard Ceska, M. John Chapman, Paul M. Dodson, Paola Fioretto, Henry N. Ginsberg, Takashi Kadowaki, Jean-Marc Lablanche, Nikolaus Marx, Jorge Plutzky, Željko Reiner, Robert S. Rosenson, Bart Staels, Jane K. Stock, Rody Sy, Christoph Wanner, Alberto Zambon & Paul Zimmet. (2008) The Residual Risk Reduction Initiative: A Call to Action to Reduce Residual Vascular Risk in Patients with Dyslipidemia. The American Journal of Cardiology 102:10, pages 1K-34K.
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Alice Y. Y. Cheng & Lawrence A. Leiter. (2008) PPAR-alpha: therapeutic role in diabetes-related cardiovascular disease. Diabetes, Obesity and Metabolism 10:9, pages 691-698.
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Charles R. Harper & Terry A. Jacobson. (2008) Managing Dyslipidemia in Chronic Kidney Disease. Journal of the American College of Cardiology 51:25, pages 2375-2384.
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C. P. Lin, Y. H. Chen, W. T. Lin, H. B. Leu, T. Z. Liu, S. L. Huang & J. W. Chen. (2008) Direct effect of statins on homocysteine-induced endothelial adhesiveness: potential impact to human atherosclerosis. European Journal of Clinical Investigation 38:2, pages 106-116.
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Charles R. McQuade, Jennifer Griego, Joe Anderson & Amy Barton Pai. (2008) Elevated serum creatinine levels associated with fenofibrate therapy. American Journal of Health-System Pharmacy 65:2, pages 138-141.
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Genovefa D Kolovou, Peggy M Kostakou, Katherine K Anagnostopoulou & Dennis V Cokkinos. (2008) Therapeutic Effects of Fibrates in Postprandial Lipemia. American Journal of Cardiovascular Drugs 8:4, pages 243-255.
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Giulia Chinetti-GbaguidiBart Staels. (2007) Measuring biomarkers to assess the therapeutic effects of PPAR agonists?. Pharmacogenomics 8:11, pages 1567-1580.
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Carol M. Baldwin, Iris R. Bell, Anna Giuliano, Mary Z. Mays, Pete Arambula & Andrei Alexandrov. (2007) Differences in Mexican American and Non-Hispanic White Veterans' Homocysteine Levels. Journal of Nursing Scholarship 39:3, pages 235-242.
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Anthony S Wierzbicki. (2016) Homocysteine and cardiovascular disease: a review of the evidence. Diabetes and Vascular Disease Research 4:2, pages 143-149.
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HEIKKI ERIK NIKKANEN & MICHAEL W. SHANNON. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 317 345 .
Bruno Vergès. (2006) Fenofibrate therapy and cardiovascular protection in diabetes: recommendations after FIELD. Current Opinion in Lipidology 17:6, pages 653-658.
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Scott M Smith, Susan A Mathews Oliver, Sara R Zwart, Geeta Kala, P. Adam Kelly, James S Goodwin & Carmel B Dyer. (2006) Nutritional Status Is Altered in the Self-Neglecting Elderly. The Journal of Nutrition 136:10, pages 2534-2541.
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Anna L. Berg, Arnar T. Rafnsson, Magnus Johannsson, Björn Hultberg & Margret Arnadottir. (2006) The effects of adrenocorticotrophic hormone and cortisol on homocysteine and vitamin B concentrations. Clinical Chemistry and Laboratory Medicine (CCLM) 44:5.
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Giulia Chinetti-Gbaguidi, Jean Charles Fruchart & Bart Staels. (2005) Pleiotropic effects of fibrates. Current Atherosclerosis Reports 7:5, pages 396-401.
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Angelika de Bree, Pilar Galan & Louise Mennen. 2005. Food-Drug Synergy and Safety. Food-Drug Synergy and Safety 77 109 .

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