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Review

The risks and the benefits of mesalazine as a treatment for ulcerative colitis

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Pages 99-107 | Published online: 16 Mar 2007

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Bharat Kumar Reddy Sanapalli, Elango Kannan, Shivaramakrishnan Balasubramanian, Jawahar Natarajan, Uday Krishna Baruah & Veera Venkata Satyanarayana Reddy Karri. (2018) Pluronic lecithin organogel of 5-aminosalicylic acid for wound healing. Drug Development and Industrial Pharmacy 44:10, pages 1650-1658.
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Kavinderjit Nanda & Alan C Moss. (2012) Update on the management of ulcerative colitis: treatment and maintenance approaches focused on MMX® mesalamine. Clinical Pharmacology: Advances and Applications 4, pages 41-50.
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Maggie Ham & Alan C Moss. (2012) Mesalamine in the treatment and maintenance of remission of ulcerative colitis. Expert Review of Clinical Pharmacology 5:2, pages 113-123.
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Garrett Lawlor, Awais Ahmed & Alan C Moss. (2010) Once-daily mesalamine granules for ulcerative colitis. Expert Review of Clinical Immunology 6:4, pages 521-526.
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Laura Noddin Rosenberg & Mark A Peppercorn. (2010) Efficacy and safety of drugs for ulcerative colitis. Expert Opinion on Drug Safety 9:4, pages 573-592.
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Mary Y Hu & Mark A Peppercorn. (2008) MMX mesalamine: a novel high-dose, once-daily 5-aminosalicylate formulation for the treatment of ulcerative colitis. Expert Opinion on Pharmacotherapy 9:6, pages 1049-1058.
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Articles from other publishers (30)

Joanna Słoka, Marcel Madej & Barbara Strzalka-Mrozik. (2023) Molecular Mechanisms of the Antitumor Effects of Mesalazine and Its Preventive Potential in Colorectal Cancer. Molecules 28:13, pages 5081.
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Wenlong Fu, Lei Xie, Jicheng Yu, Yanjun He, Jie Zeng, Jian Liu, Kang Liang, Pu Chen, Lei Jiang, Zhen Gu & Biao Kong. (2023) In Situ Interfacial Super-Assembly of Nanobiohybrids through Plant for Food-Grade Oral Medicine . ACS Applied Materials & Interfaces 15:5, pages 7282-7293.
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Shraddha Saha, Jinal Naik, Natarajan Amaresan & Meonis Pithawala. (2022) In silico analysis of Typha domingensis Pers. phytocompounds against wound healing biomarkers and ascertaining through in vitro cell migration assay. 3 Biotech 12:8.
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Sasha R. Fehily, Aysha H. Al‐Ani, Jonathan Abdelmalak, Clarissa Rentch, Eva Zhang, Justin T. Denholm, Douglas Johnson, Siew C. Ng, Vishal Sharma, David T. Rubin, Peter R. Gibson & Britt Christensen. (2022) Review article: latent tuberculosis in patients with inflammatory bowel diseases receiving immunosuppression—risks, screening, diagnosis and management. Alimentary Pharmacology & Therapeutics 56:1, pages 6-27.
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Simran Shergill. (2021) Mesalazine-induced myopericarditis: a case report. European Heart Journal - Case Reports 5:2.
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Richa Chibbar & Alan C. Moss. (2020) Mesalamine in the Initial Therapy of Ulcerative Colitis. Gastroenterology Clinics of North America 49:4, pages 689-704.
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Sasha R. Fehily, Felicity C. Martin & Michael A. Kamm. (2019) Simple water‐based tacrolimus enemas for refractory proctitis. JGH Open 4:4, pages 561-564.
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Shiva T. Radhakrishnan, Aruchuna Mohanaruban & Sami Hoque. (2018) Mesalazine-induced myocarditis: a case report. Journal of Medical Case Reports 12:1.
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Hilal Ahmad & Vijay L. Kumar. (2018) Pharmacotherapy of ulcerative colitis – current status and emerging trends. Journal of Basic and Clinical Physiology and Pharmacology 29:6, pages 581-592.
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Sasha R. Fehily, Nik M. Partsanis & Britt Christensen. (2018) Cough in the Immunosuppressed Patient. Gastroenterology.
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Frank Karkossa & Sandra Klein. (2018) A Biopredictive In Vitro Comparison of Oral Locally Acting Mesalazine Formulations by a Novel Dissolution Model for Assessing Intraluminal Drug Release in Individual Subjects. Journal of Pharmaceutical Sciences 107:6, pages 1680-1689.
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Paisit Paueksakon & Agnes B Fogo. (2017) Drug-induced nephropathies. Histopathology 70:1, pages 94-108.
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Gary R. Lichtenstein, Glenn L. Gordon, Salam Zakko, Uma Murthy, Shahriar Sedghi, Ron Pruitt, Andrew C. Barrett, Enoch Bortey, Craig Paterson & William P. Forbes. (2015) Long-Term Benefit of Mesalamine Granules for Patients Who Achieved Corticosteroid-Induced Ulcerative Colitis Remission. Digestive Diseases and Sciences 61:1, pages 221-229.
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Bei Ye. (2015) Mesalazine preparations for the treatment of ulcerative colitis: Are all created equal?. World Journal of Gastrointestinal Pharmacology and Therapeutics 6:4, pages 137.
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Maricelma da Silva Soares de Souza, Sandra Maria Barbalho, Ricardo de Alvares Goulart & Antonely de Cássio Alves de Carvalho. (2015) The Current and Future Role of Drugs and Probiotics in the Management of Inflammatory Bowel Disease. Journal of Biosciences and Medicines 03:08, pages 76-85.
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Anita Annaházi & Tamás Molnár. (2015) Optimal Endpoint of Therapy in IBD: An Update on Factors Determining a Successful Drug Withdrawal. Gastroenterology Research and Practice 2015, pages 1-18.
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Marine Auffret, Johana Béné, Marc Lambert & Sophie Gautier. (2014) Pneumopathie interstitielle diffuse sous mésalazine : un effet indésirable sous diagnostiqué ?. Therapies 69:6, pages 531-532.
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Hannah L. Miller & Francis A. Farraye. 2014. Pocket Guide to Gastrointestinal Drugs. Pocket Guide to Gastrointestinal Drugs 82 99 .
Kousaku Kawashima, Shunji Ishihara, Takafumi Yuki, Koji Onishi, Yoshinori Kushiyama, Hirofumi Fujishiro, Youichi Miyaoka, Mika Yuki, Yoshinori Komazawa, Takashi Tanimura, Hiroki Sonoyama, Yasumasa Tada, Ryusaku Kusunoki, Akihiko Oka, Nobuhiko Fukuba, Naoki Oshima, Ichiro Moriyama & Yoshikazu Kinoshita. (2014) Therapeutic Efficacy of pH-Dependent Release Formulation of Mesalazine on Active Ulcerative Colitis Resistant to Time-Dependent Release Formulation: Analysis of Fecal Calprotectin Concentration. BioMed Research International 2014, pages 1-6.
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Per Karlén. (2013) Mesalazine-induced renal calculi. American Journal of Case Reports 14, pages 551-553.
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Pascal Frei, Luc Biedermann, Christine N. Manser, Maike Wilk, Michael Manz, Stephan R. Vavricka & Gerhard Rogler. (2012) Topical Therapies in Inflammatory Bowel Disease. Digestion 86:s1, pages 36-44.
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Volker Gross, Ivan Bunganic, Elena A. Belousova, Tatyana L. Mikhailova, Limas Kupcinskas, Gediminas Kiudelis, Zsolt Tulassay, Libor Gabalec, Andrey E. Dorofeyev, Jelena Derova, Karin Dilger, Roland Greinwald & Ralph Mueller. (2011) 3g mesalazine granules are superior to 9mg budesonide for achieving remission in active ulcerative colitis: A double-blind, double-dummy, randomised trial. Journal of Crohn's and Colitis 5:2, pages 129-138.
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G. R. Lichtenstein, G. L. Gordon, S. Zakko, U. Murthy, S. Sedghi, R. Pruitt, K. Merchant, A. Shaw, E. Bortey & W. P. Forbes. (2010) Clinical trial: once‐daily mesalamine granules for maintenance of remission of ulcerative colitis – a 6‐month placebo‐controlled trial. Alimentary Pharmacology & Therapeutics 32:8, pages 990-999.
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Mark A. Perazella & Glen S. Markowitz. (2010) Drug-induced acute interstitial nephritis. Nature Reviews Nephrology 6:8, pages 461-470.
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Bruno Sposato, Maria Pia Allegri, Maria Piera Riccardi, Silvia Chigiotti, Cesira Nencioni, Barbara Ricciardi, Tiziana Carli, Alberto Cresti, Maria Grazia Perari, Maria Giovanna Migliorini & Mario Toti. (2012) Mesalazine-Induced Multi-Organ Hypersensitivity. Clinical Drug Investigation 30:6, pages 413-417.
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Mirna Djuric, Djordje Povazan, Svetozar Secen & Jelena Jovic. (2010) Differential diagnosis problem of pulmonary changes in ulcerative colitis. Vojnosanitetski pregled 67:6, pages 511-514.
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Pim J. Koelink, Lukas J.A.C. Hawinkels, Eliza Wiercinska, Cornelis F.M. Sier, Peter ten Dijke, Cornelis B.H.W. Lamers, Daan W. Hommes & Hein W. Verspaget. (2010) 5-Aminosalicylic acid inhibits TGF-β1 signalling in colorectal cancer cells. Cancer Letters 287:1, pages 82-90.
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Yusuf Usta, Hasan Ozen, Figen Gurakan, Nuray Uslu, Inci Nur Saltik-Temizel, Hulya Demir & Aysel Yuce. (2009) Hypereosinophilia Due to Mesalazine Treatment. Journal of Clinical Gastroenterology 43:4, pages 382.
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M.R. Atienza Amores, I. Martín-Garrido, R. García-Contreras & J.M. Varela Aguilar. (2009) Alopecia como reacción adversa de la mesalazina. Revista Clínica Española 209:3, pages 153-154.
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Nielsen Q Fernandez-Becker & Alan C Moss. (2008) Improving Delivery of Aminosalicylates in Ulcerative Colitis. Drugs 68:8, pages 1089-1103.
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