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Levodopa delivery systems: advancements in delivery of the gold standard

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Pages 203-224 | Published online: 24 Jan 2010

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Francesco Trotta, Fabrizio Caldera, Roberta Cavalli, Marco Soster, Chiara Riedo, Miriam Biasizzo, Gloria Uccello Barretta, Federica Balzano & Valentina Brunella. (2016) Molecularly imprinted cyclodextrin nanosponges for the controlled delivery of L-DOPA: perspectives for the treatment of Parkinson’s disease. Expert Opinion on Drug Delivery 13:12, pages 1671-1680.
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Livia Dézsi & László Vécsei. (2014) Clinical implications of irregular ADMET properties with levodopa and other antiparkinson's drugs. Expert Opinion on Drug Metabolism & Toxicology 10:3, pages 409-424.
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Tamás Kiss, Rita Ambrus, Mohamed M. Abdelghafour, Scarlett Zeiringer, Atiđa Selmani, Eva Roblegg, Mária Budai-Szűcs, László Janovák, Bálint Lőrinczi, Ágota Deák, Andreas Bernkop-Schnürch & Gábor Katona. (2022) Preparation and detailed characterization of the thiomer chitosan–cysteine as a suitable mucoadhesive excipient for nasal powders. International Journal of Pharmaceutics, pages 122188.
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Yinying Wang, Rongsha Chen, Zhongshan Yang, Qian Wen, Xia Cao, Ninghui Zhao & Jinyuan Yan. (2022) Protective Effects of Polysaccharides in Neurodegenerative Diseases. Frontiers in Aging Neuroscience 14.
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Moslem Mansour Lakouraj, Masoume Rezaei & Vahid Hasantabar. (2021) Synthesis, characterization and in-vitro prolonged release of L-DOPA using a novel amphiphilic hydrogel based on sodium alginate-polypyrrole. International Journal of Biological Macromolecules 193, pages 609-618.
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Haitham Bukhary, Gareth R. Williams & Mine Orlu. (2020) Fabrication of Electrospun Levodopa-Carbidopa Fixed-Dose Combinations. Advanced Fiber Materials 2:4, pages 194-203.
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Álvaro R. Ruiz-Fernández, Felipe Villanelo, Sebastian E. Gutierrez-Maldonado, Claudia Pareja-Barrueto, Boris E. Weiss-López & Tomas Perez-Acle. (2020) l -DOPA modulates the kinetics but not the thermodynamic equilibrium of TTA + amphiphiles forming lyotropic nematic liquid crystals . RSC Advances 10:26, pages 15366-15374.
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Benedicta Obenewaa Dankyi, Seth Kwabena Amponsah, Grace Lovia Allotey-Babington, Ismaila Adams, Nana Aboadwe Goode & Henry Nettey. (2020) Chitosan-Coated Hydroxypropylmethyl Cellulose Microparticles of Levodopa (and Carbidopa): In Vitro and Rat Model Kinetic Characteristics. Current Therapeutic Research 93, pages 100612.
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Tamás Kiss, Tünde Alapi, Gábor Varga, Csilla Bartos, Rita Ambrus, Piroska Szabó-Révész & Gábor Katona. (2019) Interaction Studies Between Levodopa and Different Excipients to Develop Coground Binary Mixtures for Intranasal Application. Journal of Pharmaceutical Sciences 108:8, pages 2552-2560.
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Chaohua Li, Yanan Sun, Weifeng Yang, Shuhua Ma, Lili Zhang, Jing Zhao, Xin Zhao & Yi Wang. (2019) Pilose Antler Extracts (PAEs) Protect against Neurodegeneration in 6-OHDA-Induced Parkinson’s Disease Rat Models. Evidence-Based Complementary and Alternative Medicine 2019, pages 1-11.
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Vidhi Shah, Mukesh Sharma, Radhika Pandya, Rajesh K. Parikh, Bhavesh Bharatiya, Atindra Shukla & Hsieh-Chih Tsai. (2017) Quality by Design approach for an in situ gelling microemulsion of Lorazepam via intranasal route. Materials Science and Engineering: C 75, pages 1231-1241.
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Ndidi C. Ngwuluka, Yahya E. Choonara, Pradeep Kumar, Lisa C. du Toit, Girish Modi & Viness Pillay. (2015) An optimized gastroretentive nanosystem for the delivery of levodopa. International Journal of Pharmaceutics 494:1, pages 49-65.
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Marcel M. Miyake & Benjamin S. Bleier. (2015) Bypassing the blood–brian barrier using established skull base reconstruction techniques. World Journal of Otorhinolaryngology - Head and Neck Surgery 1:1, pages 11-16.
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Marcel Menon Miyake & Benjamin S. Bleier. (2015) The Blood-Brain Barrier and Nasal Drug Delivery to the Central Nervous System. American Journal of Rhinology & Allergy 29:2, pages 124-127.
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Anroop B. Nair, Rachna Kumria, Sumeet Gupta & Bandar E. Al-Dhubiab. (2014) Development and Evaluation of a Novel Drug in Adhesive Transdermal System of Levodopa and Carbidopa. Journal of Pharmaceutical Innovation 9:4, pages 302-308.
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Nicholas A. Young, Michael S. Bruss, Mark Gardner, William L. Willis, Xiaokui Mo, Giancarlo R. Valiente, Yu Cao, Zhongfa Liu, Wael N. Jarjour & Lai-Chu Wu. (2014) Oral Administration of Nano-Emulsion Curcumin in Mice Suppresses Inflammatory-Induced NFκB Signaling and Macrophage Migration. PLoS ONE 9:11, pages e111559.
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Masahiko Tomiyama. 2014. Adenosine Receptors in Neurology and Psychiatry. Adenosine Receptors in Neurology and Psychiatry 117 126 .
Krithika Mohanraj, Swaminathan Sethuraman & Uma Maheswari Krishnan. (2013) Development of poly(butylene succinate) microspheres for delivery of levodopa in the treatment of Parkinson's disease. Journal of Biomedical Materials Research Part B: Applied Biomaterials 101B:5, pages 840-847.
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Ndidi C. Ngwuluka, Yahya E. Choonara, Girish Modi, Lisa C. du Toit, Pradeep Kumar, Valence M. K. Ndesendo & Viness Pillay. (2013) Design of an Interpolyelectrolyte Gastroretentive Matrix for the Site-Specific Zero-Order Delivery of Levodopa in Parkinson’s Disease. AAPS PharmSciTech 14:2, pages 605-619.
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