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Review

Strategies to improve oral drug bioavailability

Pages 419-433 | Published online: 10 May 2005

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Haiyan Zhang, Youlin Yang, Yi Chen, Xiahui Zhang & Xiaopei Chen. (2023) A convergent fabrication of programmed pH/reduction-responsive nanoparticles for efficient dual anticancer drugs delivery for ovarian cancer treatment. Journal of Experimental Nanoscience 18:1.
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Jerneja Kladnik, Ana Dolinar, Jakob Kljun, David Perea, Judith Grau-Expósito, Meritxell Genescà, Marko Novinec, Maria J. Buzon & Iztok Turel. (2022) Zinc pyrithione is a potent inhibitor of PLPro and cathepsin L enzymes with ex vivo inhibition of SARS-CoV-2 entry and replication. Journal of Enzyme Inhibition and Medicinal Chemistry 37:1, pages 2158-2168.
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Susbin Raj Wagle, Bozica Kovacevic, Daniel Walker, Corina Mihaela Ionescu, Umar Shah, Goran Stojanovic, Sanja Kojic, Armin Mooranian & Hani Al-Salami. (2020) Alginate-based drug oral targeting using bio-micro/nano encapsulation technologies. Expert Opinion on Drug Delivery 17:10, pages 1361-1376.
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Alex Laux, Chrisna Gouws & Josias H. Hamman. (2019) Aloe vera gel and whole leaf extract: functional and versatile excipients for drug delivery?. Expert Opinion on Drug Delivery 16:12, pages 1283-1285.
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Lorena Segale, Lorella Giovannelli, Paolo Mannina & Franco Pattarino. (2015) Formulation and characterization study of itraconazole-loaded microparticles. Pharmaceutical Development and Technology 20:2, pages 153-158.
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Matthew Crum, Amal Ali Elkordy, Moataz Zarara & Eman Ali Elkordy. (2013) In situ lyophilisation of nifedipine directly in hard gelatine capsules. Pharmaceutical Development and Technology 18:6, pages 1379-1390.
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Luana Perioli & Cinzia Pagano. (2012) Inorganic matrices: an answer to low drug solubility problem. Expert Opinion on Drug Delivery 9:12, pages 1559-1572.
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Dennis Douroumis. (2011) Orally disintegrating dosage forms and taste-masking technologies; 2010. Expert Opinion on Drug Delivery 8:5, pages 665-675.
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Rivka Yatuv, Micah Robinson, Inbal Dayan & Moshe Baru. (2010) Enhancement of the efficacy of therapeutic proteins by formulation with PEGylated liposomes; a case of FVIII, FVIIa and G-CSF. Expert Opinion on Drug Delivery 7:2, pages 187-201.
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Gill M. Enslin, Josias H. Hamman & Awie F. Kotzé. (2008) Intestinal Drug Absorption Enhancers: Synergistic Effects of Combinations. Drug Development and Industrial Pharmacy 34:12, pages 1343-1349.
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Michael Brandl, Xiaoyang Wu, Marites Holper, Lei Hong, Zhongjiang Jia, Raj Birudaraj, Micaela Reddy, Tom Alfredson, Tony Tran, Susan Larrabee, Xu Hadig, Keshab Sarma, Carla Washington, George Hill & David B. Smith. (2008) Physicochemical Properties of the Nucleoside Prodrug R1626 Leading to High Oral Bioavailability. Drug Development and Industrial Pharmacy 34:7, pages 683-691.
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Seshadri Neervannan. (2006) Preclinical formulations for discovery and toxicology: physicochemical challenges. Expert Opinion on Drug Metabolism & Toxicology 2:5, pages 715-731.
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