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Review

Pectin-based oral drug delivery to the colon

Pages 441-450 | Published online: 10 May 2005

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Wujie Zhang, Kirsten Mary Mahuta, Brandon Anthony Mikulski, Jenna Nicole Harvestine, James Zachary Crouse, Jung Chull Lee, Matey Georgiev Kaltchev & Charles Samuel Tritt. (2016) Novel pectin-based carriers for colonic drug delivery. Pharmaceutical Development and Technology 21:1, pages 127-130.
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Kai Dong, Yalin Dong, Cuiyu You, Wei Xu, Xiaoyan Huang, Yan Yan, Lu Zhang, Ke Wang & Jianfeng Xing. (2016) Assessment of the drug loading, in vitro and in vivo release behavior of novel pH-sensitive hydrogel. Drug Delivery 23:1, pages 174-184.
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Pornsak Sriamornsak. (2011) Application of pectin in oral drug delivery. Expert Opinion on Drug Delivery 8:8, pages 1009-1023.
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Articles from other publishers (32)

Qingbin Guo, Xiaojun Huang, Ji Kang, Huihuang Ding, Yan Liu, Nifei Wang & Steve W. Cui. (2022) Immunomodulatory and antivirus activities of bioactive polysaccharides and structure-function relationship. Bioactive Carbohydrates and Dietary Fibre 27, pages 100301.
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Selin S. Suner, Betul Ari, S. Duygu Sutekin & Nurettin Sahiner. (2022) Biocompatible poly(galacturonic acid) micro/nanogels with controllable degradation via tunable chemical crosslinking. International Journal of Biological Macromolecules 201, pages 351-363.
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Jinfeng Chen, Yanli Cui, Yunxiang Ma & Shenggui Zhang. (2022) The gelation behavior of thiolated citrus high-methoxyl pectin induced by sodium phosphate dibasic dodecahydrate. Carbohydrate Polymers 277, pages 118849.
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Rober Habashy, Mouhamad Khoder, Abdullah Isreb & Mohamed A. Alhnan. (2022) A Novel Multilayer Natural Coating for Fed-State Gastric Protection. Pharmaceutics 14:2, pages 283.
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Irina Popescu, Mihail Lupei, Marieta Constantin, Geanina Voicu, Manuela Calin, Anca Irina Prisacaru & Gheorghe Fundueanu. (2021) Double cross-linked pectin beads stable in physiological environment as potential support for biomedical applications. Journal of Polymer Research 28:11.
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Oksana Zaitseva, Andrey Khudyakov, Marta Sergushkina, Olga Solomina & Tatyana Polezhaeva. (2020) Pectins as a universal medicine. Fitoterapia 146, pages 104676.
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Qiaobin Hu, Siqi Hu, Erika Fleming, Ji-Young Lee & Yangchao Luo. (2020) Chitosan-caseinate-dextran ternary complex nanoparticles for potential oral delivery of astaxanthin with significantly improved bioactivity. International Journal of Biological Macromolecules 151, pages 747-756.
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Badrul Hisyam Zainudin, Tin Wui Wong & Halimaton Hamdan. 2020. Polymer Science and Innovative Applications. Polymer Science and Innovative Applications 257 286 .
Huihuang Ding & Steve W. Cui. 2020. Pectin: Technological and Physiological Properties. Pectin: Technological and Physiological Properties 165 188 .
Claudia Lara-Espinoza, Elizabeth Carvajal-Millán, René Balandrán-Quintana, Yolanda López-Franco & Agustín Rascón-Chu. (2018) Pectin and Pectin-Based Composite Materials: Beyond Food Texture. Molecules 23:4, pages 942.
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Manisha Buriuli, Wasupalli Geeta Kumari & Devendra Verma. (2017) Evaluation of hemostatic effect of polyelectrolyte complex-based dressings. Journal of Biomaterials Applications 32:5, pages 638-647.
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Aqdas Noreen, Zill-i-Huma Nazli, Javeria Akram, Ijaz Rasul, Asim Mansha, Nazia Yaqoob, Rehana Iqbal, Shazia Tabasum, Mohammad Zuber & Khalid Mahmood Zia. (2017) Pectins functionalized biomaterials; a new viable approach for biomedical applications: A review. International Journal of Biological Macromolecules 101, pages 254-272.
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Adel Penhasi. (2017) Preparation and characterization of in-situ ionic cross-linked pectin films: II. Biodegradation and drug diffusion. Carbohydrate Polymers 157, pages 651-659.
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James Z. Crouse, Kirsten M. Mahuta, Brandon A. Mikulski, Jenna N. Harvestine, Xiaoru Guo, Jung C. Lee, Matey G. Kaltchev, Katarina S. Midelfort, Charles S. Tritt, Junhong Chen & Wujie Zhang. (2015) Development of a Microscale Red Blood Cell-Shaped Pectin-Oligochitosan Hydrogel System Using an Electrospray-Vibration Method: Preparation and Characterization. Journal of Applied Biomaterials & Functional Materials 13:4, pages 326-331.
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Abbas Akhgari. (2015) Role of Polysaccharides in Colon-Specific Drug Delivery. Jundishapur Journal of Natural Pharmaceutical Products 10:3.
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George Dan Mogoşanu & Alexandru Mihai Grumezescu. 2015. Handbook of Polymers for Pharmaceutical Technologies. Handbook of Polymers for Pharmaceutical Technologies 477 519 .
Yao Liu, Yan Sun, Guanglong Ding, Qianqian Geng, Juanli Zhu, Mingcheng Guo, Yongheng Duan, Baitao Wang & Yongsong Cao. (2015) Synthesis, Characterization, and Application of Microbe-Triggered Controlled-Release Kasugamycin–Pectin Conjugate. Journal of Agricultural and Food Chemistry 63:17, pages 4263-4268.
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Cheng-Yi Lin, Hsiu-Hui Peng, Mei-Hsiu Chen, Jui-Sheng Sun, Tse-Ying Liu & Ming-Hong Chen. (2015) In situ forming hydrogel composed of hyaluronate and polygalacturonic acid for prevention of peridural fibrosis. Journal of Materials Science: Materials in Medicine 26:4.
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Luca Palugan, Matteo Cerea, Lucia Zema, Andrea Gazzaniga & Alessandra Maroni. (2015) Coated pellets for oral colon delivery. Journal of Drug Delivery Science and Technology 25, pages 1-15.
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Adel Penhasi & Victor M. Meidan. (2014) Preparation and characterization of in situ ionic cross-linked pectin films: Unique biodegradable polymers. Carbohydrate Polymers 102, pages 254-260.
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Alessandra Maroni, Maria Dorly Del Curto, Lucia Zema, Anastasia Foppoli & Andrea Gazzaniga. (2013) Film coatings for oral colon delivery. International Journal of Pharmaceutics 457:2, pages 372-394.
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Helene Jonassen, Alessandro Treves, Anna-Lena Kjøniksen, Gro Smistad & Marianne Hiorth. (2013) Preparation of Ionically Cross-Linked Pectin Nanoparticles in the Presence of Chlorides of Divalent and Monovalent Cations. Biomacromolecules 14:10, pages 3523-3531.
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Anita K. Verma & A. Kumar. (2013) Pharmacokinetics and biodistribution of negatively charged pectin nanoparticles encapsulating paclitaxel. Cancer Nanotechnology 4:4-5, pages 99-102.
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Hsiu-Hui Peng, Yi-Min Chen, Chen-I Lee & Ming-Wei Lee. (2013) Synthesis of a disulfide cross-linked polygalacturonic acid hydrogel for biomedical applications. Journal of Materials Science: Materials in Medicine 24:6, pages 1375-1382.
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Raj Kumar Dutta & Saurabh Sahu. (2012) Development of diclofenac sodium loaded magnetic nanocarriers of pectin interacted with chitosan for targeted and sustained drug delivery. Colloids and Surfaces B: Biointerfaces 97, pages 19-26.
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Saurabh Sahu & Raj Kumar Dutta. (2011) Novel hybrid nanostructured materials of magnetite nanoparticles and pectin. Journal of Magnetism and Magnetic Materials 323:7, pages 980-987.
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Jiasheng Tu, Yan Shen, Ravichandran Mahalingam, Bhaskara Jasti & Xiaoling Li. 2010. Oral Controlled Release Formulation Design and Drug Delivery. Oral Controlled Release Formulation Design and Drug Delivery 71 87 .
Linda Salbu, Annette Bauer-Brandl & Ingunn Tho. (2009) Direct Compression Behavior of Low- and High-Methoxylated Pectins. AAPS PharmSciTech 11:1, pages 18-26.
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Sayeh Majzoob, Fatemeh Atyabi, Farid Dorkoosh, Krum Kafedjiiski, Brigitta Loretz & Andreas Bernkop-Schnürch. (2006) Pectin-cysteine conjugate: synthesis and in-vitro evaluation of its potential for drug delivery. Journal of Pharmacy and Pharmacology 58:12, pages 1601-1610.
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Ellen Hagesaether, Marianne Hiorth & Sverre Arne Sande. (2009) Mucoadhesion and drug permeability of free mixed films of pectin and chitosan: An in vitro and ex vivo study. European Journal of Pharmaceutics and Biopharmaceutics 71:2, pages 325-331.
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Sandrine Bourgeois, Nicolas Tsapis, Helge Honnas, Antoine Andremont, Monjed Shakweh, Madeleine Besnard & Elias Fattal. (2008) Colonic Delivery of β‐Lactamases Does not Affect Amoxicillin Pharmacokinetics in Rats. Journal of Pharmaceutical Sciences 97:5, pages 1853-1863.
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Ellen Hagesaether, Ragnar Bye & S. Arne Sande. (2008) Ex vivo mucoadhesion of different zinc-pectinate hydrogel beads. International Journal of Pharmaceutics 347:1-2, pages 9-15.
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