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Review

Biomedical aspects of targeted delivery of drugs to pulmonary endothelium

Pages 909-926 | Published online: 16 Sep 2005

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Kai Yue, Chao Yang, Yu You, Xueying Wang & Xinxin Zhang. (2023) Experimental Investigation of Temperature Influence on Nanoparticle Adhesion in an Artificial Blood Vessel. International Journal of Nanomedicine 18, pages 425-436.
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Jacob S Brenner, Colin Greineder, Vladimir Shuvaev & Vladimir Muzykantov. (2015) Endothelial nanomedicine for the treatment of pulmonary disease. Expert Opinion on Drug Delivery 12:2, pages 239-261.
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Jonathan T Sutton, Kevin J Haworth, Gail Pyne-Geithman & Christy K Holland. (2013) Ultrasound-mediated drug delivery for cardiovascular disease. Expert Opinion on Drug Delivery 10:5, pages 573-592.
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Yi-Xuan Li, Hong-Bo Wang, Jing Li, Jian-Bo Jin, Jing-Bo Hu & Chun-Lin Yang. (2022) Targeting pulmonary vascular endothelial cells for the treatment of respiratory diseases. Frontiers in Pharmacology 13.
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Rubiya Khursheed, Keshav R Paudel, Monica Gulati, Sukriti Vishwas, Niraj Kumar Jha, Philip M Hansbro, Brian G Oliver, Kamal Dua & Sachin Kumar Singh. (2022) Expanding the arsenal against pulmonary diseases using surface-functionalized polymeric micelles: breakthroughs and bottlenecks. Nanomedicine 17:12, pages 881-911.
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Erika M. J. Siren, Haiming D. Luo, Sargun Bajaj, Jordan MacKenzie, Masoud Daneshi, D. Mark Martinez, Edward M. Conway, Karen C. Cheung & Jayachandran N. Kizhakkedathu. (2021) An improved in vitro model for studying the structural and functional properties of the endothelial glycocalyx in arteries, capillaries and veins. The FASEB Journal 35:6.
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Patrick M. Glassman, Landis R. Walsh, Carlos H. Villa, Oscar A. Marcos-Contreras, Elizabeth D. Hood, Vladimir R. Muzykantov & Colin F. Greineder. (2020) Molecularly Engineered Nanobodies for Tunable Pharmacokinetics and Drug Delivery. Bioconjugate Chemistry 31:4, pages 1144-1155.
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Elizabeth D. Hood, Colin F. Greineder, Tea Shuvaeva, Landis Walsh, Carlos H. Villa & Vladimir R. Muzykantov. (2018) Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies. Bioconjugate Chemistry 29:11, pages 3626-3637.
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Raisa Yu. Kiseleva, Patrick M. Glassman, Colin F. Greineder, Elizabeth D. Hood, Vladimir V. Shuvaev & Vladimir R. Muzykantov. (2017) Targeting therapeutics to endothelium: are we there yet?. Drug Delivery and Translational Research 8:4, pages 883-902.
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Raisa Yu. Kiseleva, C. F. Greineder, C. H. Villa, O. A. Marcos-Contreras, E. D. Hood, V. V. Shuvaev, H. M. DeLisser & V. R. Muzykantov. (2018) Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1). Scientific Reports 8:1.
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Jacob S. Brenner, Raisa Yu. Kiseleva, Patrick M. Glassman, Hamideh Parhiz, Colin F. Greineder, Elizabeth D. Hood, Vladimir V. Shuvaev & Vladimir R. Muzykantov. (2018) The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety (2017 Grover Conference Series). Pulmonary Circulation 8:1, pages 1-18.
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G. A. Efimov, J. M. H. Raats, R. G. S. Chirivi, J. W. G. van Rosmalen & S. A. Nedospasov. (2017) Humanization of Murine Monoclonal anti-hTNF Antibody: The F10 Story. Molecular Biology 51:6, pages 921-926.
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Xiang Gao, Regis R. Vollmer & Song Li. 2015. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials 6875 6893 .
Elizabeth D. Hood, Vladimir V. Shuvaev & Vladimir R. Muzykantov. 2016. Oxidative Stress and Biomaterials. Oxidative Stress and Biomaterials 323 349 .
Vladimir V. Shuvaev, Jacob S. Brenner & Vladimir R. Muzykantov. (2015) Targeted endothelial nanomedicine for common acute pathological conditions. Journal of Controlled Release 219, pages 576-595.
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Jacob W. Myerson, Jacob S. Brenner, Colin F. Greineder & Vladimir R. Muzykantov. (2015) Systems approaches to design of targeted therapeutic delivery. WIREs Systems Biology and Medicine 7:5, pages 253-265.
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Melissa D. Howard, Elizabeth D. Hood, Colin F. Greineder, Ivan S. Alferiev, Michael Chorny & Vladimir Muzykantov. (2014) Targeting to Endothelial Cells Augments the Protective Effect of Novel Dual Bioactive Antioxidant/Anti-Inflammatory Nanoparticles. Molecular Pharmaceutics 11:7, pages 2262-2270.
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Melissa Howard, Blaine J. Zern, Aaron C. Anselmo, Vladimir V. Shuvaev, Samir Mitragotri & Vladimir Muzykantov. (2014) Vascular Targeting of Nanocarriers: Perplexing Aspects of the Seemingly Straightforward Paradigm. ACS Nano 8:5, pages 4100-4132.
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Jin Liu, Portonovo S. Ayyaswamy, David M. Eckmann & Ravi Radhakrishnan. (2013) Modelling of binding free energy of targeted nanocarriers to cell surface. Heat and Mass Transfer 50:3, pages 315-321.
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Melissa D. HowardElizabeth D. HoodBlaine ZernVladimir V. ShuvaevTilo GrosserVladimir R. Muzykantov. (2014) Nanocarriers for Vascular Delivery of Anti-Inflammatory Agents. Annual Review of Pharmacology and Toxicology 54:1, pages 205-226.
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Aaron C. Anselmo, Vivek Gupta, Blaine J. Zern, Daniel Pan, Michael Zakrewsky, Vladimir Muzykantov & Samir Mitragotri. (2013) Delivering Nanoparticles to Lungs while Avoiding Liver and Spleen through Adsorption on Red Blood Cells. ACS Nano 7:12, pages 11129-11137.
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Maria Ansar, Daniel Serrano, Iason Papademetriou, Tridib Kumar Bhowmick & Silvia Muro. (2013) Biological Functionalization of Drug Delivery Carriers To Bypass Size Restrictions of Receptor-Mediated Endocytosis Independently from Receptor Targeting. ACS Nano 7:12, pages 10597-10611.
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Colin F. Greineder, Ann-Marie Chacko, Sergei Zaytsev, Blaine J. Zern, Ronald Carnemolla, Elizabeth D. Hood, Jingyan Han, Bi-Sen Ding, Charles T. Esmon & Vladimir R. Muzykantov. (2013) Vascular Immunotargeting to Endothelial Determinant ICAM-1 Enables Optimal Partnering of Recombinant scFv-Thrombomodulin Fusion with Endogenous Cofactor. PLoS ONE 8:11, pages e80110.
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Vladimir R. Muzykantov. (2013) Targeted Drug Delivery to Endothelial Adhesion Molecules. ISRN Vascular Medicine 2013, pages 1-27.
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Portonovo S. Ayyaswamy, Vladimir Muzykantov, David M. Eckmann & Ravi Radhakrishnan. (2013) Nanocarrier Hydrodynamics and Binding in Targeted Drug Delivery: Challenges in Numerical Modeling and Experimental Validation. Journal of Nanotechnology in Engineering and Medicine 4:1.
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Silvia Muro. (2012) Challenges in design and characterization of ligand-targeted drug delivery systems. Journal of Controlled Release 164:2, pages 125-137.
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Silvia Muro. (2012) Strategies for delivery of therapeutics into the central nervous system for treatment of lysosomal storage disorders. Drug Delivery and Translational Research 2:3, pages 169-186.
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Ann-Marie Chacko, Madhura Nayak, Colin F. Greineder, Horace M. DeLisser & Vladimir R. Muzykantov. (2012) Collaborative Enhancement of Antibody Binding to Distinct PECAM-1 Epitopes Modulates Endothelial Targeting. PLoS ONE 7:4, pages e34958.
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Tian Yu, Khaled Greish, Lawrence D. McGill, Abhijit Ray & Hamidreza Ghandehari. (2012) Influence of Geometry, Porosity, and Surface Characteristics of Silica Nanoparticles on Acute Toxicity: Their Vasculature Effect and Tolerance Threshold. ACS Nano 6:3, pages 2289-2301.
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Jingyan HanVladimir V ShuvaevVladimir R Muzykantov. (2012) Targeted interception of signaling reactive oxygen species in the vascular endothelium. Therapeutic Delivery 3:2, pages 263-276.
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Bi-Sen Ding, Daniel J. Nolan, Peipei Guo, Alexander O. Babazadeh, Zhongwei Cao, Zev Rosenwaks, Ronald G. Crystal, Michael Simons, Thomas N. Sato, Stefan Worgall, Koji Shido, Sina Y. Rabbany & Shahin Rafii. (2011) Endothelial-Derived Angiocrine Signals Induce and Sustain Regenerative Lung Alveolarization. Cell 147:3, pages 539-553.
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B. Uma, T. N. Swaminathan, P. S. Ayyaswamy, D. M. Eckmann & R. Radhakrishnan. (2011) Generalized Langevin dynamics of a nanoparticle using a finite element approach: Thermostating with correlated noise. The Journal of Chemical Physics 135:11.
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Erez Koren & Vladimir P. Torchilin. (2011) Drug carriers for vascular drug delivery. IUBMB Life 63:8, pages 586-595.
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Vladimir R. Muzykantov. (2011) Targeted therapeutics and nanodevices for vascular drug delivery: Quo vadis?. IUBMB Life 63:8, pages 583-585.
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B. Uma, T. N. Swaminathan, R. Radhakrishnan, D. M. Eckmann & P. S. Ayyaswamy. (2011) Nanoparticle Brownian motion and hydrodynamic interactions in the presence of flow fields. Physics of Fluids 23:7.
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Vladimir V. Shuvaev & Vladimir R. Muzykantov. (2011) Targeted modulation of reactive oxygen species in the vascular endothelium. Journal of Controlled Release 153:1, pages 56-63.
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Jin Liu, Neeraj J. Agrawal, Andres Calderon, Portonovo S. Ayyaswamy, David M. Eckmann & Ravi Radhakrishnan. (2011) Multivalent Binding of Nanocarrier to Endothelial Cells under Shear Flow. Biophysical Journal 101:2, pages 319-326.
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Ann-Marie Chacko, Elizabeth D. Hood, Blaine J. Zern & Vladimir R. Muzykantov. (2011) Targeted nanocarriers for imaging and therapy of vascular inflammation. Current Opinion in Colloid & Interface Science 16:3, pages 215-227.
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Silvia Muro & Vladimir R. Muzykantov. 2010. Organelle-Specific Pharmaceutical Nanotechnology. Organelle-Specific Pharmaceutical Nanotechnology 449 474 .
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Silvia Muro, Carmen Garnacho, Julie A Champion, John Leferovich, Christine Gajewski, Edward H Schuchman, Samir Mitragotri & Vladimir R Muzykantov. (2008) Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers. Molecular Therapy 16:8, pages 1450-1458.
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Carmen Garnacho, Vladimir Shuvaev, Anu Thomas, Lindsay McKennaJing SunMichael Koval, Steven AlbeldaVladimir Muzykantov & Silvia Muro. (2008) RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1. Blood 111:6, pages 3024-3033.
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Bi-Sen DingNankang HongJuan-Carlos MurcianoKumkum GangulyClaudia GottsteinMelpo Christofidou-SolomidouSteven M. AlbeldaAron B. FisherDouglas B. Cines & Vladimir R. Muzykantov. (2008) Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature. Blood 111:4, pages 1999-2006.
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Thomas D. Dziubla, Vladimir V. Shuvaev, Nan Kang Hong, Brian J. Hawkins, Muniswamy Madesh, Hajime Takano, Eric Simone, Marian T. Nakada, Aron Fisher, Steven M. Albelda & Vladimir R. Muzykantov. (2008) Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies. Biomaterials 29:2, pages 215-227.
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Vladimir V. Shuvaev, Samira Tliba, Marian Nakada, Steven M. Albelda & Vladimir R. Muzykantov. (2007) Platelet-Endothelial Cell Adhesion Molecule-1-Directed Endothelial Targeting of Superoxide Dismutase Alleviates Oxidative Stress Caused by Either Extracellular or Intracellular Superoxide. Journal of Pharmacology and Experimental Therapeutics 323:2, pages 450-457.
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Yiyao Liu, Hirokazu Miyoshi & Michihiro Nakamura. (2007) Novel drug delivery system of hollow mesoporous silica nanocapsules with thin shells: Preparation and fluorescein isothiocyanate (FITC) release kinetics. Colloids and Surfaces B: Biointerfaces 58:2, pages 180-187.
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Vladimir V. Shuvaev, Melpo Christofidou-Solomidou, Arnaud Scherpereel, Eric Simone, Evguenia Arguiri, Samira Tliba, Jeremy Pick, Stephen Kennel, Steven M. Albelda & Vladimir R. Muzykantov. (2007) Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium. Journal of Controlled Release 118:2, pages 235-244.
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Silvia Muro, Thomas Dziubla, Weining Qiu, John Leferovich, Xiumin Cui, Erik Berk & Vladimir R. Muzykantov. (2006) Endothelial Targeting of High-Affinity Multivalent Polymer Nanocarriers Directed to Intercellular Adhesion Molecule 1. Journal of Pharmacology and Experimental Therapeutics 317:3, pages 1161-1169.
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